A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model

scientific article published on 17 July 2015

A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1052119190
P356DOI10.1186/S12885-015-1538-9
P932PMC publication ID4504175
P698PubMed publication ID26177924
P5875ResearchGate publication ID280121519

P2093author name stringAnja Bastian
Aleem Gangjee
Rheal A Towner
Debra Saunders
Nataliya Smith
Michael Ihnat
Roheeth Kumar Pavana
P2860cites workAngiogenesis in patients with craniopharyngiomas: correlation with treatment and outcome.Q54623906
Paclitaxel (TAXOL®) concentrations in brain tumor tissueQ72109363
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agentQ27679191
Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2Q28487568
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011.Q30402063
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009.Q30447832
Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potentialQ33636107
Single chain anti-c-Met antibody conjugated nanoparticles for in vivo tumor-targeted imaging and drug deliveryQ33816457
Potential role of ABC transporters as a detoxification system at the blood-CSF barrier.Q33981559
Glioma morphology and tumor‐induced vascular alterations revealed in seven rodent glioma models by in vivo magnetic resonance imaging and angiographyQ34041524
Prevalence estimates for primary brain tumors in the United States by age, gender, behavior, and histologyQ34132943
Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour modelQ34198939
Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: analysis of single-agent and combined modality approachesQ34515465
Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markersQ34815207
The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastomaQ35053326
Novel therapies in glioblastomaQ35864136
Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expressionQ36193529
ELTD1, a potential new biomarker for gliomasQ36564447
Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007.Q36627197
Heterogeneity of tumor vasculature and antiangiogenic intervention: insights from MR angiography and DCE-MRI.Q37510240
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylasesQ37544152
Current therapeutic paradigms in glioblastomaQ37703345
Glioma proteomics: status and perspectives.Q37717824
Multiparametric assessment of the anti-glioma properties of OKN007 by magnetic resonance imaging.Q39717688
MDA-MB-435 and M14 cell lines: identical but not M14 melanoma?Q39834203
Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas.Q40265290
Drug resistance in brain tumorsQ40560888
Induction of O6-methylguanine-DNA-methyltransferase and N3-methyladenine-DNA-glycosylase in human cells exposed to DNA-damaging agentsQ41561865
Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B.Q45003993
Combined molecular MRI and immuno-spin-trapping for in vivo detection of free radicals in orthotopic mouse GL261 gliomasQ45777378
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)522
P577publication date2015-07-17
P1433published inBMC CancerQ326300
P1476titleA new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model
P478volume15

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cites work (P2860)
Q42700872AG488 as a therapy against gliomas
Q58550001Development and characterization of sorafenib-loaded lipid nanocapsules for the treatment of glioblastoma
Q41086093Different expression of miR-29b and VEGFA in glioma
Q38728583Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents
Q38646275Live-cell calcium imaging of adherent and non-adherent GL261 cells reveals phenotype-dependent differences in drug responses.
Q64926957Microtubule targeting agents in glioma.
Q54213332Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System® (RTS®) gene switch as gene therapy for the treatment of glioma.