RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation

scientific article published on 28 November 2005

RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M507771200
P932PMC publication ID1831550
P698PubMed publication ID16317010

P2093author name stringPedro A Jose
Regina M Day
Robert J Lechleider
Shiyou Chen
Jennifer E Leader
Michelle Crawford
Victorino R Briones
P2860cites workTransforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanismQ24600173
PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fateQ24683266
The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formationQ28207920
Smad-dependent and Smad-independent pathways in TGF-beta family signallingQ28208250
p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neuronsQ28587133
The pathogenesis of atherosclerosis: a perspective for the 1990sQ29547827
Transcriptional control by the TGF-beta/Smad signaling systemQ29618985
Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerizationQ30306237
L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism.Q30433980
Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.Q33334687
Developmental biology of the vascular smooth muscle cell: building a multilayered vessel wallQ33537227
Specificity, diversity, and regulation in TGF-beta superfamily signaling.Q33792305
Role of Ras and Mapks in TGFbeta signalingQ33857574
Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoAQ34011759
Molecular control of neural crest formation, migration and differentiationQ34076847
Smad proteins regulate transcriptional induction of the SM22alpha gene by TGF-betaQ34771801
Transforming growth factor beta (TGFbeta) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT).Q35846514
Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42.Q38342615
Downregulation of N-cadherin in the neointima stimulates migration of smooth muscle cells by RhoA deactivation.Q38343583
Transforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK.Q40404500
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivoQ40497387
Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanismQ40527668
RhoA and Rac1 are both required for efficient wound closure of airway epithelial cellsQ40527674
Transforming growth factor-beta-induced differentiation of smooth muscle from a neural crest stem cell lineQ40570886
HOXB7 overexpression promotes differentiation of C3H10T1/2 cells to smooth muscle cells.Q40875479
In vitro system for differentiating pluripotent neural crest cells into smooth muscle cellsQ41052260
Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinasesQ42802765
Sildenafil prevents change in RhoA expression induced by chronic hypoxia in rat pulmonary artery.Q44567721
Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotoninQ45009104
Phenotypic features of smooth muscle cells during the evolution of experimental carotid artery intimal thickening. Biochemical and morphologic studiesQ45028368
Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractilityQ46387635
A Role for Rho in Smooth Muscle Phenotypic RegulationQ57702970
Cytoskeletal features of normal and atheromatous human arterial smooth muscle cellsQ69618965
Coronary smooth muscle differentiation from proepicardial cells requires rhoA-mediated actin reorganization and p160 rho-kinase activityQ77469542
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1765-1770
P577publication date2005-11-28
P1433published inJournal of Biological ChemistryQ867727
P1476titleRhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation
P478volume281

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cites work (P2860)
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