Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expression

scientific article published on August 1994

Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expression is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1994PNAS...91.8398L
P356DOI10.1073/PNAS.91.18.8398
P932PMC publication ID44613
P698PubMed publication ID8078893
P5875ResearchGate publication ID15120142

P2093author name stringRowan S
Ben-David Y
Lu SJ
Bani MR
P2860cites workA mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulatorsQ24310682
Human erythroid 5-aminolevulinate synthase: promoter analysis and identification of an iron-responsive element in the mRNAQ24315090
Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virusQ24559244
A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†Q24605651
Cis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase geneQ28279066
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1Q28508495
Rescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cellsQ28510862
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper proteinQ29620253
Unidirectional digestion with exonuclease III in DNA sequence analysisQ29620554
Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirusQ33354120
Spi-1 oncogene activation in Rauscher and Friend murine virus-induced acute erythroleukemiasQ33885671
Detailed analysis of the site 3 region of the human beta-globin dominant control regionQ33920690
Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.Q34114085
p53: oncogene or anti-oncogene?Q34627381
A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiationQ35839474
The 5'HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sitesQ35925421
Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietinQ36675415
Retroviral insertions downstream of the heterogeneous nuclear ribonucleoprotein A1 gene in erythroleukemia cells: evidence that A1 is not essential for cell growthQ36703019
Structure and expression of the chicken ferritin H-subunit geneQ36840198
A safe packaging line for gene transfer: separating viral genes on two different plasmidsQ36865708
Friend virus-induced erythroleukemia and the multistage nature of cancerQ37296781
Tumorigenesis by slow-transforming retroviruses--an updateQ38012047
Oncogenes at viral integration sitesQ38025712
The LCR-like α-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiationQ40411508
Characterization of the major regulatory element upstream of the human alpha-globin gene clusterQ40640470
Insertional inactivation of the p53 gene during friend leukemia: a new strategy for identifying tumor suppressor genesQ41716902
Temporal order and functional analysis of mutations within the Fli-1 and p53 genes during the erythroleukemias induced by F-MuLV.Q42809548
Inactivation of the p53 oncogene by internal deletion or retroviral integration in erythroleukemic cell lines induced by Friend leukemia virusQ45841107
Structure of the human ferrochelatase gene. Exon/intron gene organization and location of the gene to chromosome 18.Q48179150
Spi-1 is a putative oncogene in virally induced murine erythroleukaemias.Q53523856
Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2Q59060564
The PU.1 transcription factor is the product of the putative oncogene Spi-1Q68840600
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)8398-8402
P577publication date1994-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleRetroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expression
P478volume91

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cites work (P2860)
Q44642038A WW domain-binding motif within the activation domain of the hematopoietic transcription factor NF-E2 is essential for establishment of a tissue-specific histone modification pattern
Q35679582A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2.
Q33943083Activation of beta-major globin gene transcription is associated with recruitment of NF-E2 to the beta-globin LCR and gene promoter
Q36082540Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.
Q64101656Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations
Q39663498Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake.
Q41009510Bb1-3, a transgenic hybrid cell line with erythroid and megakaryocytic differentiation potential that expresses high levels of human gamma-globin and human beta-globin
Q42510960Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice
Q34563260ChIPs of the beta-globin locus: unraveling gene regulation within an active domain
Q40291965Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci.
Q28594933Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus
Q34056545Conditional expression of the ubiquitous transcription factor MafK induces erythroleukemia cell differentiation
Q34154290Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain
Q40016988Dependence of globin gene expression in mouse erythroleukemia cells on the NF-E2 heterodimer
Q24603214Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells
Q34675849Dissecting long-range transcriptional mechanisms by chromatin immunoprecipitation
Q40145000Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation.
Q74484742Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter
Q41692278Distinction between AP1 and NF-E2 factor-binding at specific chromatin regions in mammalian cells
Q37416523Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells
Q44327227Dynamic regulation of histone H3 methylated at lysine 79 within a tissue-specific chromatin domain.
Q40875517Ectopic expression of transcription factor NF-E2 alters the phenotype of erythroid and monoblastoid cells.
Q58576444Emerging Regulatory Role of Nrf2 in Iron, Heme, and Hemoglobin Metabolism in Physiology and Disease
Q33958941Enhancement of beta-globin locus control region-mediated transactivation by mitogen-activated protein kinases through stochastic and graded mechanisms
Q37087623Epigenetic control of complex loci during erythropoiesis
Q36970205Erythroid and megakaryocytic transformation
Q28219123Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins
Q33919156Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2
Q36557554Establishment and regulation of chromatin domains: mechanistic insights from studies of hemoglobin synthesis.
Q24517781Fli-1, an Ets-related transcription factor, regulates erythropoietin-induced erythroid proliferation and differentiation: evidence for direct transcriptional repression of the Rb gene during differentiation
Q40849706Functional characterization of the two alternative promoters of human p45 NF-E2 gene
Q34393399Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain
Q35920505Highly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain
Q42421191HnRNP A1 tethers KSRP to an exon splicing silencer that inhibits an erythroid-specific splicing event in PU.1-induced erythroleukemia
Q34766721Influence of a short-term iron-deficient diet on hepatic gene expression profiles in rats
Q28201249Interaction of NF-E2 in the human beta-globin locus control region before chromatin remodeling
Q24313410Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II
Q33825632Introduction of a cis-acting mutation in the capsid-coding gene of moloney murine leukemia virus extends its leukemogenic properties
Q36987792Iron deficiency: lessons from anemic mice
Q24564535Isolation of a differentially regulated splicing isoform of human NF-E2
Q33591572JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells
Q24657480Locus control regions
Q73088343Loss of p53 in F-MuLV induced-erythroleukemias accelerates the acquisition of mutational events that confers immortality and growth factor independence
Q41118648Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells
Q28513444MRG15 regulates embryonic development and cell proliferation
Q40177569Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation
Q36217970Mitogen-activated protein kinases enhance long-range activation by the beta-globin locus control region
Q46822896Multiclonal pattern of Jaagsiekte sheep retrovirus integration sites in ovine pulmonary adenocarcinoma.
Q39720357Multiple regions of p45 NF-E2 are required for beta-globin gene expression in erythroid cells
Q41354231Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest
Q24292362NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor
Q28610614NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro
Q29620011NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
Q33343998Nuclear factor-erythroid 2 (NF-E2) expression in normal and malignant megakaryocytopoiesis
Q33947034Nuclear relocation of a transactivator subunit precedes target gene activation.
Q40601294Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase.
Q29037128Regulation and function of the NFE2 transcription factor in hematopoietic and non-hematopoietic cells
Q40460475Regulation of Globin Gene Expression in Erythroid Cells
Q47873129Regulation of mouse p45 NF-E2 transcription by an erythroid-specific GATA-dependent intronic alternative promoter
Q64381275Requirement of an E1A-sensitive coactivator for long-range transactivation by the beta-globin locus control region
Q33600935Requirements for utilization of CREB binding protein by hypersensitive site two of the beta-globin locus control region
Q37014084Small Maf proteins (MafF, MafG, MafK): History, structure and function
Q34150764Sumoylation of p45/NF-E2: nuclear positioning and transcriptional activation of the mammalian beta-like globin gene locus
Q24680482Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation
Q24317348Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice
Q33503111The NF-E2 transcription factor
Q36580348The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the alpha- and beta-globin gene loci in an erythroid cell line
Q42686276The regional integration of retroviral sequences into the mosaic genomes of mammals
Q37611347The transcription factor, Nuclear factor, erythroid 2 (Nfe2), is a regulator of the oxidative stress response during Danio rerio development
Q40021128The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2.
Q41011070Transcription factor erythroid Krüppel-like factor (EKLF) is essential for the erythropoietin-induced hemoglobin production but not for proliferation, viability, or morphological maturation
Q40612891Transcription factors and hematopoietic development
Q34700755Transcriptional control of erythropoiesis: emerging mechanisms and principles.
Q41442502Transcriptional control of globin gene switching during vertebrate development
Q33855140USF and NF-E2 cooperate to regulate the recruitment and activity of RNA polymerase II in the beta-globin gene locus
Q46130409cAMP-dependent protein kinase is necessary for increased NF-E2.DNA complex formation during erythroleukemia cell differentiation
Q33887503p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes
Q28507068p45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induced erythroleukemias

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