The bone-protective effect of genistein in the animal model of bilateral ovariectomy: roles of phytoestrogens and PTH/PTHR1 against post-menopausal osteoporosis

scientific article published on 22 December 2011

The bone-protective effect of genistein in the animal model of bilateral ovariectomy: roles of phytoestrogens and PTH/PTHR1 against post-menopausal osteoporosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS13010056
P932PMC publication ID3269672
P698PubMed publication ID22312238
P5875ResearchGate publication ID221812568

P2093author name stringJin Zhang
Qing Miao
Shan Miao
Song Zhang
Nan Hu
Jian-Bo Wang
Jing-Ge Li
Si-Wang Wang
Yan-Hua Xie
P2860cites workQuantification of genistein and genistin in soybeans and soybean products.Q50612238
Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 1-year randomized, double-blind, placebo-controlled study.Q50774964
Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial.Q50776071
Pharmacological studies of the large-scaled purified genistein from Huaijiao (Sophora japonica-Leguminosae) on anti-osteoporosis.Q51777881
Apoptosis during bone-like tissue development in vitro.Q52191626
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Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy studyQ74590315
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Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosisQ29619487
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Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiolQ33359381
Protective effect of genistein aglycone on the development of osteonecrosis of the femoral head and secondary osteoporosis induced by methylprednisolone in ratsQ33424230
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Epidemiology and outcomes of osteoporotic fracturesQ34671295
Anti-photoaging effects of soy isoflavone extract (aglycone and acetylglucoside form) from soybean cakeQ35002115
Phyto-oestrogensQ35145593
Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on boneQ35990474
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Genistein aglycone reverses glucocorticoid-induced osteoporosis and increases bone breaking strength in rats: a comparative study with alendronateQ37230770
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Continuous parathyroid hormone and estrogen administration increases vertebral cancellous bone volume and cortical width in the estrogen-deficient rat.Q43671910
Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogensQ43716911
Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese dietQ43917257
Japanese intake of flavonoids and isoflavonoids from foodsQ44111957
Effects of synthetic and plant-derived selective modulators of estrogen receptors on depression-like behavior of female ratsQ46162121
NO-donating genistein prodrug alleviates bone loss in ovariectomised ratsQ46304614
Effects of phytoestrogen genistein on cytogenetic biomarkers in postmenopausal women: 1 year randomized, placebo-controlled study.Q46549826
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)56-70
P577publication date2011-12-22
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleThe bone-protective effect of genistein in the animal model of bilateral ovariectomy: roles of phytoestrogens and PTH/PTHR1 against post-menopausal osteoporosis
P478volume13

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cites work (P2860)
Q36906317Biomechanical properties of osteoporotic rat femurs after different hormonal treatments: genistein, estradiol, and estradiol/progesterone
Q35014332Chemopreventive and chemotherapeutic effects of genistein, a soy isoflavone, upon cancer development and progression in preclinical animal models
Q33582576Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines
Q36883244Effect of formononetin on mechanical properties and chemical composition of bones in rats with ovariectomy-induced osteoporosis
Q47394908Exploring molecular mechanism of bone-forming capacity of Eurycoma longifolia: Evidence of enhanced expression of bone-related biomarkers.
Q38025048Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling.
Q35145132Genistein attenuates glucocorticoid-induced bone deleterious effects through regulation Eph/ephrin expression in aged mice
Q38182167Medicinal herbs in the prevention and treatment of osteoporosis
Q36137320Micellar emulsions composed of mPEG-PCL/MCT as novel nanocarriers for systemic delivery of genistein: a comparative study with micelles
Q38734163Mulberry water extract regulates the osteoblast/osteoclast balance in an ovariectomic rat model
Q33800445PROTECTIVE EFFECT OF VANILLIC ACID ON OVARIECTOMY-INDUCED OSTEOPOROSIS IN RATS.
Q37198934Polygonatum sibiricum polysaccharide inhibits osteoporosis by promoting osteoblast formation and blocking osteoclastogenesis through Wnt/β-catenin signalling pathway.
Q38740554Standardized Sophora pachycarpa Root Extract Enhances Osteogenic Differentiation in Adipose-derived Human Mesenchymal Stem Cells
Q88674065The phytoestrogen genistein prevents trabecular bone loss and affects thyroid follicular cells in a male rat model of osteoporosis

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