Clusterin attenuates the development of renal fibrosis

scientific article published on 3 November 2011

Clusterin attenuates the development of renal fibrosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1681/ASN.2011010048
P932PMC publication ID3269926
P698PubMed publication ID22052058

P2093author name stringIn-Kyu Lee
Mi-Kyung Kim
Keun-Gyu Park
Gwon-Soo Jung
Hye-Soon Kim
Jung-Guk Kim
Yun-A Jung
Ki-Up Lee
In-Sun Park
Bon-Hong Min
P2860cites workIdentification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor betaQ38331875
A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritisQ39793286
Activin A is a potent activator of renal interstitial fibroblastsQ40604314
Synthesis and functional analyses of nuclear clusterin, a cell death proteinQ40674770
Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative propertiesQ41038445
Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injuryQ43067030
Clusterin protects renal tubular epithelial cells from gentamicin-mediated cytotoxicityQ43906902
Modulation of different clusterin isoforms in human colon tumorigenesisQ44750584
Blockade of TGF-beta action ameliorates renal dysfunction and histologic progression in anti-GBM nephritis.Q45862669
Bone marrow mononuclear cells attenuate interstitial fibrosis and stimulate the repair of tubular epithelial cells after unilateral ureteral obstructionQ46310557
Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathyQ46393305
TGF-beta1 siRNA suppresses the tubulointerstitial fibrosis in the kidney of ureteral obstructionQ46916569
Multifunctionality of PAI-1 in fibrogenesis: evidence from obstructive nephropathy in PAI-1-overexpressing mice.Q50766818
Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells.Q53499214
Plasmin(ogen) Promotes Renal Interstitial Fibrosis by Promoting Epithelial-to-Mesenchymal Transition: Role of Plasmin-Activated SignalsQ57741352
PAI-1 deficiency attenuates the fibrogenic response to ureteral obstructionQ57741393
Clusterin is up-regulated in glomerular mesangial cells in complement-mediated injuryQ73338471
The renal expression of transforming growth factor-beta isoforms and their receptors in acute and chronic experimental diabetes in ratsQ73500725
Molecular pathological evaluation of clusterin in a rat model of unilateral ureteral obstruction as a possible biomarker of nephrotoxicityQ80206977
Quantitative gene expression analysis in a nonhuman primate model of antibiotic-induced nephrotoxicityQ80794194
Plasminogen activator inhibitor-1 gene deficiency attenuates TGF-beta1-induced kidney diseaseQ81549378
Clusterin, a novel modulator of TGF-beta signaling, is involved in Smad2/3 stabilityQ28261241
Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathyQ30448126
Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditisQ30532828
Evaluation of novel biomarkers of nephrotoxicity in two strains of rat treated with CisplatinQ33661304
Plasminogen activator inhibitor 1: physiological and pathophysiological roles.Q33958024
Transforming growth factor-beta signal transduction and progressive renal diseaseQ33963170
HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy.Q33976494
Plasminogen activator inhibitor type 1 is a potential target in renal fibrogenesisQ34067658
Clusterin/apolipoprotein J in human aging and cancerQ34146411
Apolipoprotein J/clusterin prevents a progressive glomerulopathy of agingQ34323718
Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulationQ34527773
Clusterin protects H9c2 cardiomyocytes from oxidative stress-induced apoptosis via Akt/GSK-3β signaling pathwayQ34587120
Obstructive nephropathy and renal fibrosisQ34953429
Pathogenesis of fibrosis: role of TGF-beta and CTGF.Q34985703
Reactive oxygen species and matrix remodeling in diabetic kidneyQ35182366
Diabetic nephropathy and transforming growth factor-beta: transforming our view of glomerulosclerosis and fibrosis build-upQ35590527
Mammalian transforming growth factor-betas: Smad signaling and physio-pathological roles.Q35756439
Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouseQ35842105
Clusterin and Alzheimer's disease.Q36040356
Mediators of fibrosis and apoptosis in obstructive uropathiesQ36046140
Evidence that inhibition of tubular cell apoptosis protects against renal damage and development of fibrosis following ureteric obstructionQ36337198
A PAI-1 mutant, PAI-1R, slows progression of diabetic nephropathyQ36677370
Interaction of transforming growth factor beta receptors with apolipoprotein J/clusterinQ36790404
PAI-1 and kidney fibrosisQ36846526
PAI-1 as a target in kidney diseaseQ36952115
Induction of clusterin by AKT--role in cytoprotection against docetaxel in prostate tumor cellsQ37418683
Chapter 9: Oxidative stress in malignant progression: The role of Clusterin, a sensitive cellular biosensor of free radicalsQ37624996
TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy.Q37627056
Assessment of cisplatin-induced nephrotoxicity by microarray technologyQ38296612
P433issue1
P304page(s)73-85
P577publication date2011-11-03
P1433published inJournal of the American Society of NephrologyQ17123893
P1476titleClusterin attenuates the development of renal fibrosis
P478volume23

Reverse relations

cites work (P2860)
Q33941969Antifibrotic effects of KS370G, a caffeamide derivative, in renal ischemia-reperfusion injured mice and renal tubular epithelial cells.
Q83227242Brain clusterin protein isoforms and mitochondrial localization
Q38872845Calcium oxalate calculi-induced clusterin expression in kidney
Q34078756Clusterin/apolipoprotein J attenuates angiotensin II-induced renal fibrosis
Q35027749Comparative transcriptional profiling of 3 murine models of SLE nephritis reveals both unique and shared regulatory networks
Q35907575Comparative transcriptional profiling of renal cortex in rats with inherited stress-induced arterial hypertension and normotensive Wistar Albino Glaxo rats
Q50877034DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing.
Q35903097Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides
Q34441024Dimethylfumarate attenuates renal fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling
Q104073661Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects
Q47643373Diverse functions of clusterin promote and protect against the development of pulmonary fibrosis.
Q27005788Epigenetics of progression of chronic kidney disease: fact or fantasy?
Q92406555Gemigliptin Attenuates Renal Fibrosis Through Down-Regulation of the NLRP3 Inflammasome
Q99350177Glomerular clusterin expression is increased in diabetic nephropathy and protects against oxidative stress-induced apoptosis in podocytes
Q36760362Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor β1 (TGF-β1) activation
Q37723232Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice
Q92940908Measurements of echocardiographic indices and biomarkers of kidney injury in dogs with chronic kidney disease
Q33901411Performance of urinary neutrophil gelatinase-associated lipocalin, clusterin, and cystatin C in predicting diabetic kidney disease and diabetic microalbuminuria: a consecutive cohort study
Q36138680Relationship of clusterin with renal inflammation and fibrosis after the recovery phase of ischemia-reperfusion injury
Q37056839Renoprotective Effect of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, in Streptozotocin-Induced Type 1 Diabetic Mice.
Q38670777The CLU-files: disentanglement of a mystery
Q38149803The physiological roles of apolipoprotein J/clusterin in metabolic and cardiovascular diseases
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