review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1037023136 |
P356 | DOI | 10.1038/SJ.GT.3302270 |
P698 | PubMed publication ID | 15057265 |
P2093 | author name string | Baum C | |
Fehse B | |||
Bubenheim M | |||
Kustikova OS | |||
P2860 | cites work | LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 | Q28210584 |
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy | Q28215190 | ||
Side effects of retroviral gene transfer into hematopoietic stem cells | Q34168349 | ||
Human immunodeficiency virus type 1 DNA nuclear import and integration are mitosis independent in cycling cells | Q34227319 | ||
Modelling the molecular circuitry of cancer | Q34665971 | ||
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences | Q35637501 | ||
Distinct classes of factor-independent mutants can be isolated after retroviral mutagenesis of a human myeloid stem cell line | Q41582641 | ||
Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft | Q43513924 | ||
Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population | Q45864064 | ||
Insertion mutagenesis of embryonal carcinoma cells by retroviruses | Q69801990 | ||
Murine leukemia induced by retroviral gene marking | Q77975543 | ||
P433 | issue | 11 | |
P304 | page(s) | 879-881 | |
P577 | publication date | 2004-06-01 | |
P1433 | published in | Gene Therapy | Q15763095 |
P1476 | title | Pois(s)on--it's a question of dose... | |
P478 | volume | 11 |
Q43249231 | A method to estimate the efficiency of gene expression from an integrated retroviral vector |
Q43072196 | Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia. |
Q38772068 | Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes |
Q37237435 | Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene |
Q36341652 | Amelioration of murine sickle cell disease by nonablative conditioning and γ-globin gene-corrected bone marrow cells |
Q42238862 | An integration-defective lentivirus-based resource for site-specific targeting of an edited safe-harbour locus in the human genome. |
Q90468949 | Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity |
Q34027421 | Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect |
Q45868501 | Characteristics of lentiviral vectors harboring the proximal promoter of the vav proto-oncogene: a weak and efficient promoter for gene therapy |
Q55293161 | Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks. |
Q37162080 | Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin |
Q36793118 | Defining Clonal Color in Fluorescent Multi-Clonal Tracking |
Q89633817 | Design and Characterization of an "All-in-One" Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines |
Q64986089 | Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering. |
Q89704561 | Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel |
Q34223822 | Gammaretroviral vectors: biology, technology and application |
Q45887710 | Gene therapy bio-safety: scientific and regulatory issues |
Q40772331 | Generation of Genetically Engineered Precursor T-Cells From Human Umbilical Cord Blood Using an Optimized Alpharetroviral Vector Platform |
Q89586003 | Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion |
Q36453658 | Genotoxicity of retroviral integration in hematopoietic cells. |
Q37066334 | Human miR223 promoter as a novel myelo-specific promoter for chronic granulomatous disease gene therapy |
Q39403641 | Importance of receptor usage, Fli1 activation, and mouse strain for the stem cell specificity of 10A1 murine leukemia virus leukemogenicity |
Q33755382 | Improved Tet-responsive promoters with minimized background expression |
Q36986958 | Insertional mutagenesis and clonal dominance: biological and statistical considerations |
Q35745432 | Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice |
Q38508008 | Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis. |
Q36296320 | Limitations and challenges of genetic barcode quantification |
Q34807025 | Measurement of Cancer Cell Growth Heterogeneity through Lentiviral Barcoding Identifies Clonal Dominance as a Characteristic of In Vivo Tumor Engraftment |
Q39784739 | Mechanisms controlling titer and expression of bidirectional lentiviral and gammaretroviral vectors. |
Q64082797 | MiR-125a enhances self-renewal, lifespan, and migration of murine hematopoietic stem and progenitor cell clones |
Q37701291 | Multiplexing clonality: combining RGB marking and genetic barcoding. |
Q38720148 | Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity |
Q34440338 | Optimization of Critical Hairpin Features Allows miRNA-based Gene Knockdown Upon Single-copy Transduction |
Q92002962 | Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy |
Q35087824 | Quantification of lentiviral vector copy numbers in individual hematopoietic colony-forming cells shows vector dose-dependent effects on the frequency and level of transduction. |
Q38502837 | RGB marking facilitates multicolor clonal cell tracking |
Q38497690 | RGB marking with lentiviral vectors for multicolor clonal cell tracking |
Q45874811 | Restoration of human B-cell differentiation into NOD-SCID mice engrafted with gene-corrected CD34+ cells isolated from Artemis or RAG1-deficient patients |
Q36457016 | Retrovirus vectors: toward the plentivirus? |
Q30431585 | Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution |
Q39712155 | Self-inactivating alpharetroviral vectors with a split-packaging design |
Q37260299 | Sola dosis facit venenum. Leukemia in gene therapy trials: a question of vectors, inserts and dosage? |
Q55686928 | Spontaneous reactivation of latent HIV-1 promoters is linked to the cell cycle as revealed by a genetic-insulators-containing dual-fluorescence HIV-1-based vector. |
Q45866358 | Stable gene expression occurs from a minority of integrated HIV-1-based vectors: transcriptional silencing is present in the majority |
Q45418797 | Towards hematopoietic stem cell-mediated protection against infection with human immunodeficiency virus |
Q95266325 | Vector Copy Distribution at a Single-Cell Level Enhances Analytical Characterization of Gene-Modified Cell Therapies |