scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Jochen Hampe | Q30348904 |
Stefano Romeo | Q56936985 | ||
P2093 | author name string | Felix Stickel | |
Christian Datz | |||
Eric Trépo | |||
P2860 | cites work | Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities | Q24303914 |
PNPLA3 mediates hepatocyte triacylglycerol remodeling | Q24336530 | ||
The crystal structure, mutagenesis, and activity studies reveal that patatin is a lipid acyl hydrolase with a Ser-Asp catalytic dyad | Q27641368 | ||
EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma | Q27860783 | ||
Plasma retinol binding protein: structure and function of the prototypic lipocalin | Q28142676 | ||
Characterization of the human patatin-like phospholipase family | Q28248355 | ||
Hepatocellular carcinoma in cirrhosis: incidence and risk factors | Q28290048 | ||
In vivo uptake of chylomicron [3H]retinyl ester by rat liver: evidence for retinol transfer from parenchymal to nonparenchymal cells | Q28609128 | ||
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease | Q29614897 | ||
Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver | Q29616840 | ||
Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data | Q30675355 | ||
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis | Q33673834 | ||
The assembly and secretion of apolipoprotein B-containing lipoproteins | Q33730869 | ||
Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease | Q33777486 | ||
A feed-forward loop amplifies nutritional regulation of PNPLA3 | Q33842841 | ||
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells | Q33847621 | ||
The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis | Q34075498 | ||
Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease | Q34101705 | ||
A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis | Q34140192 | ||
Sex difference in alcohol-related organ injury. | Q34272755 | ||
Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant | Q34314416 | ||
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome | Q34503398 | ||
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis | Q34675058 | ||
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes | Q34861754 | ||
Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease | Q35423296 | ||
Knowledge of hepatocellular carcinoma screening guidelines and clinical practices among gastroenterologists | Q36349931 | ||
Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis | Q36357941 | ||
Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats | Q36684364 | ||
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes | Q36698641 | ||
Lipoproteins and Lipid Transport | Q36742106 | ||
Molecular mechanisms of alcohol-mediated carcinogenesis | Q36889966 | ||
Genetic determinants of alcoholic liver disease | Q37959931 | ||
Global burden of alcoholic liver diseases | Q38091294 | ||
Systematic review with meta-analysis: the I148M variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is significantly associated with alcoholic liver cirrhosis. | Q38233721 | ||
PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis | Q39396087 | ||
Chemical structure and the changing concept of vitamin A activity | Q40134068 | ||
Biochemical mechanisms of vitamin A action | Q40146792 | ||
The critical dimension of ethnicity in liver cirrhosis mortality statistics | Q40691541 | ||
Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma. | Q42232935 | ||
Genetic predisposition to organ-specific endpoints of alcoholism | Q42647637 | ||
The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life. | Q43024330 | ||
Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. | Q43107476 | ||
Variant in PNPLA3 is associated with alcoholic liver disease | Q43234008 | ||
PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis. | Q43611915 | ||
Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis | Q43804565 | ||
Genetic factors affecting susceptibility to alcoholic liver disease in an Indian population | Q44156776 | ||
Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans | Q44602540 | ||
Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function | Q44619799 | ||
PNPLA3 (rs738409 C>G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis. | Q44635062 | ||
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals | Q44985440 | ||
Evidence of genetic predisposition to alcoholic cirrhosis and psychosis: twin concordances for alcoholism and its biological end points by zygosity among male veterans | Q45337618 | ||
Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease | Q45713646 | ||
A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans | Q46118770 | ||
PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence. | Q51439752 | ||
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians | Q58097689 | ||
Patatin-like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease | Q63241925 | ||
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro | Q63408528 | ||
Hepatic retinol metabolism. Distribution of retinoids, enzymes, and binding proteins in isolated rat liver cells | Q70105966 | ||
Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver | Q71520059 | ||
Hepatosteatosis with hypobetalipoproteinemia | Q80061442 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | genetic variation | Q349856 |
liver disease | Q929737 | ||
steatosis | Q1365091 | ||
P304 | page(s) | 152-160 | |
P577 | publication date | 2015-06-01 | |
P1433 | published in | Hepatobiliary surgery and nutrition | Q26842328 |
P1476 | title | PNPLA3 genetic variation in alcoholic steatosis and liver disease progression | |
P478 | volume | 4 |
Q60912314 | A two gene-based risk score predicts alcoholic cirrhosis development in males with at-risk alcohol consumption |
Q47115217 | AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M. |
Q39256297 | Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation |
Q90135434 | PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age |
Q37513088 | Primary liver injury and delayed resolution of liver stiffness after alcohol detoxification in heavy drinkers with the PNPLA3 variant I148M. |
Q46067368 | Reassessment of different criteria for diagnosing post-hepatectomy liver failure: a single-center study of 1683 hepatectomy |
Q28831365 | Short-Term Hypocaloric High-Fiber and High-Protein Diet Improves Hepatic Steatosis Assessed by Controlled Attenuation Parameter |