Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration

scientific article published on 19 May 2015

Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration is …
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scholarly articleQ13442814

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P356DOI10.1016/J.BIOMATERIALS.2015.05.035
P932PMC publication ID4467543
P698PubMed publication ID26004236

P50authorSamuel I. StuppQ7411769
P2093author name stringYan Zhou
Paul Bornstein
Christina J Newcomb
Malcolm L Snead
Brad A Amendt
Yaping Lei
Zhan Huang
P2860cites workLow density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signalingQ24312809
Thrombospondin 2 potentiates notch3/jagged1 signalingQ24655423
Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesisQ24683656
Amelogenin-deficient mice display an amelogenesis imperfecta phenotypeQ28201910
Antagonistic regulation of Dlx2 expression by PITX2 and Msx2: implications for tooth developmentQ28214034
Presentation of RGDS epitopes on self-assembled nanofibers of branched peptide amphiphilesQ30483707
Hierarchical self-assembly of amelogenin and the regulation of biomineralization at the nanoscaleQ30503764
Bone regeneration mediated by biomimetic mineralization of a nanofiber matrixQ34025790
Self-assembly of peptide amphiphiles: from molecules to nanostructures to biomaterialsQ34066735
Thrombospondin 2, a matricellular protein with diverse functionsQ34096182
Self-assembly and mineralization of peptide-amphiphile nanofibersQ34103088
Epithelial-mesenchymal signalling regulating tooth morphogenesisQ34187035
Biological synthesis of tooth enamel instructed by an artificial matrixQ34209437
Amelogenins: assembly, processing and control of crystal morphologyQ34375929
A simplified genetic design for mammalian enamelQ34609525
Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.Q34657663
Matricellular proteins as modulators of cell-matrix interactions: adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2.Q34763728
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Neural crest and tooth morphogenesis.Q35086432
Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularityQ35127842
Thrombospondins: structure and regulation of expressionQ35492222
Matricellular proteins in cardiac adaptation and diseaseQ35542423
The role of thrombospondins 1 and 2 in the regulation of cell-matrix interactions, collagen fibril formation, and the response to injuryQ35749745
An integrated gene regulatory network controls stem cell proliferation in teethQ35829857
Mineralization of peptide amphiphile nanofibers and its effect on the differentiation of human mesenchymal stem cellsQ36007626
The role of nanoscale architecture in supramolecular templating of biomimetic hydroxyapatite mineralization.Q36104420
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Review: extracellular matrix regulates tooth morphogenesisQ36425143
Essential roles of ameloblastin in maintaining ameloblast differentiation and enamel formationQ36447973
The cellular origin of fibronectin in the basement membrane zone of developing tooth.Q36463639
The role of bioactive nanofibers in enamel regeneration mediated through integrin signals acting upon C/EBPα and c-JunQ36692656
Affecting tooth morphology and renewal by fine-tuning the signals mediating cell and tissue interactionsQ36915311
The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation.Q37080787
Bioactive nanofibers instruct cells to proliferate and differentiate during enamel regenerationQ37203462
Integrin signalling at a glanceQ37271581
Intrinsically disordered enamel matrix protein ameloblastin forms ribbon-like supramolecular structures via an N-terminal segment encoded by exon 5Q37311861
Beta1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1.Q37426688
Development of bioactive peptide amphiphiles for therapeutic cell deliveryQ37455469
Thrombospondin-2 and extracellular matrix assemblyQ38179711
NF-Y and CCAAT/enhancer-binding protein alpha synergistically activate the mouse amelogenin gene.Q38314496
Folding, assembly, and aggregation of recombinant murine amelogenins with T21I and P41T point mutationsQ38542685
Identification of CCAAT/enhancer-binding protein alpha as a transactivator of the mouse amelogenin geneQ40886635
Function of beta1 integrin in oral epithelia and tooth bud morphogenesisQ40931969
Microstructure of enamel.Q41504041
Maintenance of amelogenin gene expression by transformed epithelial cells of mouse enamel organQ41599910
Signalling networks regulating dental developmentQ41657467
Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fateQ41676501
The developing enamel matrix: nature and functionQ41738167
Functional antagonism between Msx2 and CCAAT/enhancer-binding protein alpha in regulating the mouse amelogenin gene expression is mediated by protein-protein interactionQ41742168
Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling.Q41814862
Thrombospondins function as regulators of angiogenesisQ42643939
Supramolecular crafting of cell adhesionQ42826156
Identification of a fibronectin interaction site in the extracellular matrix protein ameloblastinQ42830818
Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.Q44543826
Genetic dissection ofPitx2in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migrationQ44659652
Evidence for amelogenin "nanospheres" as functional components of secretory-stage enamel matrix.Q44987880
Protein-to-protein interactions: criteria defining the assembly of the enamel organic matrix.Q45966278
Early determination and permissive expression of amelogenin transcription during mouse mandibular first molar developmentQ46207220
Altered amelogenin self-assembly based on mutations observed in human X-linked amelogenesis imperfecta (AIH1).Q46288471
Co-localization of EGF transcripts and peptides by combined immunohistochemistry and in situ hybridizationQ46594396
Characterization of human primary enamel organ epithelial cells in vitroQ46909684
The distribution of the matricellular protein thrombospondin 2 in tissues of embryonic and adult miceQ47679386
Thrombospondin-2 secreted by human umbilical cord blood-derived mesenchymal stem cells promotes chondrogenic differentiationQ48029947
Notch signalling is required for the survival of epithelial stem cells in the continuously growing mouse incisorQ51902420
The genetic basis of tooth development and dental defects.Q52012631
Antagonistic signals between BMP4 and FGF8 define the expression of Pitx1 and Pitx2 in mouse tooth-forming anlage.Q52171937
Enamel biology logodaedaly: getting to the root of the problem, or "who's on first...".Q52200865
Matricellular proteins as modulators of wound healing and the foreign body response.Q53701819
Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth developmentQ57006567
De novo gene expression detected by amelogenin gene transcript analysisQ71391244
Isolation of amelogenin-positive ameloblasts from rat mandibular incisor enamel organs by flow cytometry and fluorescence activated cell sortingQ73151873
P407language of work or nameEnglishQ1860
P1104number of pages13
P304page(s)216-228
P577publication date2015-05-19
P1433published inBiomaterialsQ15751139
P1476titleBioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration
P478volume61

Reverse relations

Q93173234Role of thrombospondin‑1 and thrombospondin‑2 in cardiovascular diseases (Review)cites workP2860

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