Less Frequent and Less Severe Flu-Like Syndrome in Interferon Beta-1a Treated Multiple Sclerosis Patients with at Least One Allele Bearing the G>C Polymorphism at Position -174 of the IL-6 Promoter Gene.

scientific article published on 18 August 2015

Less Frequent and Less Severe Flu-Like Syndrome in Interferon Beta-1a Treated Multiple Sclerosis Patients with at Least One Allele Bearing the G>C Polymorphism at Position -174 of the IL-6 Promoter Gene. is …
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scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1035441B
P356DOI10.1371/JOURNAL.PONE.0135441
P932PMC publication ID4540473
P698PubMed publication ID26285213
P5875ResearchGate publication ID281722522

P50authorMaria Pia AmatoQ56451881
Diego CentonzeQ42218235
P2093author name stringRuggero Capra
Alessandra Sottini
Diego Bertoli
Federico Serana
Luisa Imberti
Davide Maimone
Cinzia Cordioli
Ciro Florio
Elisa Puma
P2860cites workInterleukin-6 gene-174 G/C promoter polymorphism and its association with clinical profile of patients with multiple myeloma.Q53082272
Neutralization of pyrogen-induced tumour necrosis factor by its type 1 soluble receptor in guinea-pigs: effects on fever and interleukin-6 release.Q53353859
C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance.Q53850007
Cytokine gene polymorphisms in Taiwan.Q53885766
Managing adverse effects of disease-modifying agents used for treatment of multiple sclerosisQ57487166
Amelioration of flulike symptoms at the onset of interferon β- 1b therapy in multiple sclerosis by low-dose oral steroids is related to a decrease in interleukin-6 inductionQ57602164
Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosisQ57912405
Primary association of a TNF gene polymorphism with susceptibility to multiple sclerosisQ73086562
Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study GroupQ77573170
Beneficial effect of interferon-beta treatment in patients with multiple sclerosis is associated with transient increase in serum IL-6 level in response to interferon-beta injectionQ79426165
Analysis of proinflammatory and anti-inflammatory cytokine serum concentrations in patients with multiple sclerosis by using a multiplexed immunoassayQ82225806
Alleviating flu-like symptoms with dose titration and analgesics in MS patients on intramuscular interferon beta-1a therapy: a pilot studyQ94534821
Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”Q22252938
Interferon-β-1b: a review of its use in multiple sclerosisQ28299838
Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humansQ30578885
Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxinQ33393620
MxA mRNA quantification and disability progression in interferon beta-treated multiple sclerosis patientsQ35148010
Interrupted therapy: stopping and switching of the beta-interferons prescribed for MS.Q35206277
US FDA-approved disease-modifying treatments for multiple sclerosis: review of adverse effect profilesQ36058902
Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activationQ36082965
Quantitative differences in the immunomodulatory effects of Rebif and Avonex in IFN-β 1a treated multiple sclerosis patientsQ36091339
The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritisQ37385249
Corticosteroids, ibuprofen, and acetaminophen for IFNbeta-1a flu symptoms in MS: a randomized trial.Q40528206
Both paracetamol and ibuprofen are equally effective in managing flu-like symptoms in relapsing-remitting multiple sclerosis patients during interferon beta-1a (AVONEX) therapyQ40585200
Can we predict flu-like symptoms in patients with multiple sclerosis treated with interferon-beta?Q40620663
Lack of cross tolerance between LPS and muramyl dipeptide in induction of circulating TNF-alpha and IL-6 in guinea pigsQ40645006
Exacerbated febrile responses to LPS, but not turpentine, in TNF double receptor-knockout miceQ40655674
Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgeryQ40686433
Systemic but not central administration of tumor necrosis factor-alpha attenuates LPS-induced fever in ratsQ40688766
Interleukin-6 (IL-6) and the prognosis of abdominal aortic aneurysmsQ40706826
Systemic injection of TNF-alpha attenuates fever due to IL-1 beta and LPS in ratsQ40727253
Roles of interleukin 1 beta and tumor necrosis factor in lipopolysaccharide fever in ratsQ40757988
Side effect profile of interferon beta-1b in MS: results of an open label trialQ40952067
A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitroQ43458583
Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple SclerosisQ43876866
Differential modulation of interleukin-6 and interleukin-10 by diclofenac in patients undergoing major surgeryQ44098460
Time of interferon-beta 1a injection and duration of treatment affect clinical side effects and acute changes of plasma hormone and cytokine levels in multiple sclerosis patientsQ46925584
An investigation of polymorphism in the interleukin-10 gene promoterQ48054541
Injection of interferon-beta in the morning decreases flu-like syndrome in many patients with multiple sclerosisQ48319807
Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases?Q50096890
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)e0135441
P577publication date2015-08-18
P1433published inPLOS OneQ564954
P1476titleLess Frequent and Less Severe Flu-Like Syndrome in Interferon Beta-1a Treated Multiple Sclerosis Patients with at Least One Allele Bearing the G>C Polymorphism at Position -174 of the IL-6 Promoter Gene
P478volume10

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Q33883508Management of flu-like syndrome with cetirizine in patients with relapsing-remitting multiple sclerosis during therapy with interferon beta: Results of a randomized, cross-over, placebo-controlled pilot studycites workP2860

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