Molecular structure and transcriptional regulation of the gene for the platelet-derived growth factor alpha receptor in cultured vascular smooth muscle cells

scientific article published on July 1995

Molecular structure and transcriptional regulation of the gene for the platelet-derived growth factor alpha receptor in cultured vascular smooth muscle cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI118068
P932PMC publication ID185230
P698PubMed publication ID7615828
P5875ResearchGate publication ID15582974

P2093author name stringT Inagami
Y Kitami
S Uno
H Inui
P2860cites workDifferences in substrate specificities of alpha and beta platelet-derived growth factor (PDGF) receptors. Correlation with their ability to mediate PDGF transforming functionsQ41554304
The PDGF receptor alpha subunit activates p21ras and triggers DNA synthesis without interacting with rasGAP.Q42802025
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitroQ48375884
Potential Z-DNA forming sequences are highly dispersed in the human genomeQ48403807
Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.Q52245350
Evidence for hyperplasia in mesenteric resistance vessels of spontaneously hypertensive rats using a three-dimensional disector.Q54441587
Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBPQ57224011
Culture of quiescent arterial smooth muscle cells in a defined serum-free mediumQ67286250
Platelet-derived growth factor AA homodimer stimulates protein synthesis rather than dna synthesis in vascular smooth muscle cells from spontaneously hypertensive rats but not from normotensive ratsQ67464431
A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNAQ68033053
Kidney renin gene expression after renin inhibition in the marmosetQ68256406
CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cellsQ69362150
In vitro characteristics of vessels from patients with essential hypertensionQ69426264
Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal virusesQ69811700
Alterations in vascular smooth muscle mass in the spontaneously hypertensive rat. Role of cellular hypertrophy, hyperploidy, and hyperplasiaQ70448892
Two different subunits associate to create isoform-specific platelet-derived growth factor receptorsQ24307511
A common PDGF receptor is activated by homodimeric A and B forms of PDGFQ24339650
Structural and functional studies on platelet-derived growth factorQ24555662
A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6Q24563031
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteinsQ27860587
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cellsQ28276215
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcriptionQ28287446
A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitroQ28296697
Isolation of a recombinant copy of the gene encoding C/EBPQ28565641
Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epitheliumQ28569574
IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBPQ28575310
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptorsQ29616545
Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cellsQ30460026
Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?Q34661217
Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding proteinQ34991204
Platelet-derived growth factor alpha receptor gene expression: isolation and characterization of the promoter and upstream regulatory elementsQ35613078
Isolation of Z-DNA-containing plasmidsQ36600259
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agentsQ36761728
Avian retroviral long terminal repeats bind CCAAT/enhancer-binding proteinQ36767873
Synergistic action of interleukin-6 and glucocorticoids is mediated by the interleukin-6 response element of the rat alpha 2 macroglobulin geneQ36815211
Characterization of Genomic Poly(dT-dG) · Poly(dC-dA) Sequences: Structure, Organization, and ConformationQ36955229
Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injuryQ37401242
CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytesQ37452845
Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.Q38343717
The biology of platelet-derived growth factorQ39502750
d(TG)n.d(CA)n sequences upstream of the rat prolactin gene form Z-DNA and inhibit gene transcriptionQ40515204
New perspectives in hypertension research. Potentials of vascular biologyQ40764509
Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layersQ41043497
Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor typesQ41114076
PDGF alpha- and beta-receptors activate unique and common signal transduction pathwaysQ41516226
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmolecular geometryQ911331
P304page(s)558-567
P577publication date1995-07-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMolecular structure and transcriptional regulation of the gene for the platelet-derived growth factor alpha receptor in cultured vascular smooth muscle cells
P478volume96

Reverse relations

cites work (P2860)
Q40018233Cell-type-specific expression of the platelet-derived growth factor alpha receptor: a role for GATA-binding protein
Q42067728Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling.
Q28574938Fibroblast Growth Factor-2 Represses Platelet-derived Growth Factor Receptor-α (PDGFR-α) Transcription via ERK1/2-dependent Sp1 Phosphorylation and an Atypical cis-Acting Element in the Proximal PDGFR-α Promoter
Q30472819Increased nerve growth factor mRNA stability may underlie elevated nerve growth factor secretion from hypertensive vascular smooth muscle cells
Q73182971Localization of PDGF alpha-receptor in the developing and mature human kidney
Q37149351Localization of mesenchymal cells in adult mouse thymus: their abnormal distribution in mice with disorganization of thymic medullary epithelium
Q35813640Loss of CREB regulation of vascular smooth muscle cell quiescence in diabetes
Q22010594Mechanism of action and in vivo role of platelet-derived growth factor
Q41197236Oct-4 regulates alternative platelet-derived growth factor alpha receptor gene promoter in human embryonal carcinoma cells.
Q28085644PDGFRα in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer
Q28571261Peroxide-inducible Ets-1 mediates platelet-derived growth factor receptor-alpha gene transcription in vascular smooth muscle cells
Q43560107Peroxisome proliferator-activated receptor-gamma activation inhibits interleukin-1beta -mediated platelet-derived growth factor-alpha receptor gene expression via CCAAT/enhancer-binding protein-delta in vascular smooth muscle cells
Q47759730Platelet-derived growth factor induces apoptosis in vascular smooth muscle cells: roles of the Bcl-2 family
Q31834279Regulation of PDGFR-alpha in rat pulmonary myofibroblasts by staurosporine
Q35261176RhoB regulates PDGFR-beta trafficking and signaling in vascular smooth muscle cells
Q84945963Role of platelet-derived growth factor-AB in tumour growth and angiogenesis in relation with other angiogenic cytokines in multiple myeloma
Q52189742Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene.
Q31533655Troglitazone induces apoptosis via the p53 and Gadd45 pathway in vascular smooth muscle cells
Q24529131Urokinase-induced signaling in human vascular smooth muscle cells is mediated by PDGFR-beta

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