scholarly article | Q13442814 |
P50 | author | Enrica Rumiato | Q55755027 |
P2093 | author name string | Daniela Saggioro | |
Enrica Rumiato | |||
Giovanna Stoppa | |||
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Oncogenic Kras initiates leukemia in hematopoietic stem cells | Q27331698 | ||
Protein profile of tax-associated complexes | Q28207756 | ||
ras oncogenes in human cancer: a review | Q29547769 | ||
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma | Q29615115 | ||
Hyperactive Ras in developmental disorders and cancer | Q29616397 | ||
Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer | Q33554443 | ||
Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector | Q33854474 | ||
Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13II sensitizes Jurkat T cells to Ras-mediated apoptosis | Q33908852 | ||
RAS inhibitors: potential for cancer therapeutics | Q34046314 | ||
Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs | Q34060806 | ||
Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells | Q34255923 | ||
Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera | Q34276501 | ||
Molecular mechanisms of cellular transformation by HTLV-1 Tax. | Q34450092 | ||
Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer | Q34540268 | ||
The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer | Q34765346 | ||
GTPases and T cell activation | Q35096692 | ||
Suppression of HTLV-1 replication by Tax-mediated rerouting of the p13 viral protein to nuclear speckles | Q35164261 | ||
The cytoskeleton of digitonin-treated rat hepatocytes | Q36393736 | ||
HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches | Q37079191 | ||
Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation | Q37086934 | ||
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. | Q37109225 | ||
Deregulation of signaling pathways in acute myeloid leukemia | Q37240553 | ||
Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer | Q37397708 | ||
Control of cell death pathways by HTLV-1 proteins | Q37410437 | ||
Phosphoinositide signalling in cancer: beyond PI3K and PTEN. | Q37736257 | ||
Development of phosphoinositide-3 kinase pathway inhibitors for advanced cancer | Q37738756 | ||
HTLV-1 Tax: Linking transformation, DNA damage and apoptotic T-cell death | Q37766003 | ||
Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase | Q38298684 | ||
Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis | Q39021217 | ||
Enhanced MDR1 gene expression in human T-cell leukemia virus-I-infected patients offers new prospects for therapy. | Q39162048 | ||
Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone | Q39594099 | ||
Role for protein geranylgeranylation in adult T-cell leukemia cell survival | Q39919928 | ||
Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat | Q40116365 | ||
Role for Akt/protein kinase B and activator protein-1 in cellular proliferation induced by the human T-cell leukemia virus type 1 tax oncoprotein | Q40325197 | ||
Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells | Q40399507 | ||
Relevance of CREB phosphorylation in the anti-apoptotic function of human T-lymphotropic virus type 1 tax protein in serum-deprived murine fibroblasts | Q40527113 | ||
Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation. | Q40718584 | ||
Block of a mitochondrial-mediated apoptotic pathway in Tax-expressing murine fibroblasts. | Q40778754 | ||
Tax of the human T-lymphotropic virus type I transactivates promoter of the MDR-1 gene | Q41090653 | ||
Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes | Q41715443 | ||
Ras activation in normal white blood cells and childhood acute lymphoblastic leukemia. | Q41736550 | ||
Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells | Q42803458 | ||
HTLV-1 Tax protein cooperates with Ras in protecting cells from apoptosis. | Q43762842 | ||
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I. | Q44367844 | ||
Antiapoptotic effect of human T-cell leukemia virus type 1 tax protein correlates with its creb transcriptional activity. | Q45419690 | ||
A combined treatment of HeLa cells with the farnesyl protein transferase inhibitor L-744,832 and cisplatin significantly increases the therapeutic effect as compared to cisplatin monotherapy | Q46893652 | ||
Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice | Q46971529 | ||
Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells. | Q53596562 | ||
Tax-induced HTLV-I LTR transcriptional activation is modulated by phosphorylation. | Q55240909 | ||
Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. | Q55242179 | ||
T-cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: history and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomas | Q71529097 | ||
P433 | issue | 3 | |
P921 | main subject | Human T-lymphotropic virus 1 | Q1280388 |
P304 | page(s) | 219-228 | |
P577 | publication date | 2012-03-01 | |
P1433 | published in | Apoptosis | Q15749546 |
P1476 | title | Ras signaling contributes to survival of human T-cell leukemia/lymphoma virus type 1 (HTLV-1) Tax-positive T-cells | |
P478 | volume | 17 |
Q27027114 | Biosensors in clinical practice: focus on oncohematology |
Q38961040 | Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax. |
Q37644070 | Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis |
Q91644762 | Role of rat sarcoma virus mutations in cancer and potential target for cancer therapy |
Q26995410 | The modulation of apoptosis by oncogenic viruses |
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