Antibody-dependent complement-mediated cytotoxicity in sera from patients with HIV-1 infection is controlled by CD55 and CD59

scientific article published on September 1995

Antibody-dependent complement-mediated cytotoxicity in sera from patients with HIV-1 infection is controlled by CD55 and CD59 is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI118190
P932PMC publication ID185777
P698PubMed publication ID7544808
P5875ResearchGate publication ID15653924

P2093author name stringH Schmitz
B Kluxen
I Gigli
J P Zimmer
J Schmitz
M Bögel
S Aries
P2860cites workIsolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)Q22242256
Isolation of a human erythrocyte membrane glycoprotein with decay-accelerating activity for C3 convertases of the complement systemQ24301007
Human immunodeficiency virus type 1 activates the classical pathway of complement by direct C1 binding through specific sites in the transmembrane glycoprotein gp41Q24675546
Complement activation by recombinant HIV-1 glycoprotein gp120Q28237637
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brainQ29618472
Decreased binding of HIV-1 and vasoactive intestinal peptide following plasma membrane fluidization of CD4+ cells by phenytoinQ33507085
Heightened complement sensitivity of acquired immunodeficiency syndrome lymphocytes related to diminished expression of decay-accelerating factorQ33867535
Altered erythrocyte C3b receptor expression, immune complexes, and complement activation in homosexual men in varying risk groups for acquired immune deficiency syndromeQ34542184
Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuriaQ34576112
Absence of cytotoxic antibody to human immunodeficiency virus-infected cells in humans and its induction in animals after infection or immunization with purified envelope glycoprotein gp120Q34628114
Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attackQ34636237
Lysis of oncornaviruses by human serum. Isolation of the viral complement (C1) receptor and identification as p15EQ36339984
Lysis of RNA tumor viruses by human serum: direct antibody-independent triggering of the classical complement pathwayQ36359927
Complement activation by human monoclonal antibodies to human immunodeficiency virusQ36638803
The control of homologous lysisQ36705635
Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteinsQ36781270
Neutralization of human immunodeficiency virus type 1 by complement occurs by viral lysisQ36795915
Isolation of a human erythrocyte membrane protein capable of inhibiting expression of homologous complement transmembrane channelsQ37399677
Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibodyQ37399845
Lysis of pathogenic and nonpathogenic Entamoeba histolytica by human complement: methodological analysisQ39042997
Human serum lyses RNA tumour virusesQ39953990
HIV and human complement: mechanisms of interaction and biological implication.Q40769600
Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line.Q41478718
Functional activity of an HIV-1 neutralizing IgG human monoclonal antibody: ADCC and complement-mediated lysisQ41626651
Direct binding of complement component C1q to human immunodeficiency virus (HIV) and human T lymphotrophic virus-I (HTLV-I) coinfected cellsQ41677253
Complement-mediated enhancement of HIV-1 infection of the monoblastoid cell line U937.Q41718934
Antibody- and complement-mediated lysis of HIV-infected cells and inhibition of viral replicationQ41739544
Activation of complement on the surface of cells infected by human immunodeficiency virusQ41744013
Lysis of measles virus-infected cells by the purified cytolytic alternative complement pathway and antibodyQ41981035
Decreased expression of the membrane inhibitor of complement-mediated cytolysis CD59 on T-lymphocytes of HIV-infected patientsQ44207160
Endocytosis and shedding of the decay accelerating factor on human polymorphonuclear cellsQ45161545
Tumour necrosis factor-alpha increases the sensitivity of human immunodeficiency virus (HIV)-infected monocytic U937 cells to the complement-dependent cytotoxicity of sera from HIV type 1-infected individuals; role of the gp120 proteinQ45776325
Antibodies to human immunodeficiency virus in human sera induce cell-mediated lysis of human immunodeficiency virus-infected cellsQ45842647
HIV and HIV-infected cells differentially activate the human complement system independent of antibodyQ46910542
The AIDS-associated retrovirus is not sensitive to lysis or inactivation by human serum.Q53851202
Structural properties of the glycoplasmanylinositol anchor phospholipid of the complement membrane attack complex inhibitor CD59Q54275110
Sera from HTLV-III/LAV antibody-positive individuals mediate antibody-dependent cellular cytotoxicity against HTLV-III/LAV-infected T cells.Q55243137
Complement Activation by gp160 Glycoprotein of HIV-1Q57723278
Killing of human cytomegalovirus-infected fibroblasts by antiviral antibody and complementQ58382134
Membrane attack complex (MAC)-mediated damage to spermatozoa: protection of the cells by the presence on their membranes of MAC inhibitory proteinsQ67896269
Differences between the binding sites of the complement regulatory proteins DAF, CR1, and factor H on C3 convertasesQ68955481
A novel membrane glycoprotein capable of inhibiting membrane attack by homologous complementQ69152113
Interaction of non-antibody factors with HIV in plasmaQ72100779
Membrane cofactor protein (CD46) protects cells predominantly from alternative complement pathway-mediated C3-fragment deposition and cytolysisQ72842824
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcytotoxicityQ246181
P304page(s)1520-1526
P577publication date1995-09-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleAntibody-dependent complement-mediated cytotoxicity in sera from patients with HIV-1 infection is controlled by CD55 and CD59
P478volume96

Reverse relations

cites work (P2860)
Q34749137A high-affinity inhibitor of human CD59 enhances complement-mediated virolysis of HIV-1: implications for treatment of HIV-1/AIDS
Q33997980A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement
Q56517281Analysis of complement-mediated lysis of SIV and SIV-infected cells reveals sex differences in vaccine-induced immune responses in Rhesus macaques
Q40518684Analysis of the interaction between respiratory syncytial virus and lipid-rafts in Hep2 cells during infection.
Q41556124Association of complement receptor 2 polymorphisms with innate resistance to HIV-1 infection
Q35973601Blockage of CD59 Function Restores Activities of Neutralizing and Nonneutralizing Antibodies in Triggering Antibody-Dependent Complement-Mediated Lysis of HIV-1 Virions and Provirus-Activated Latently Infected Cells
Q36158037CD59 incorporation protects hepatitis C virus against complement-mediated destruction.
Q34610122Complement and HIV-I infection/HIV-associated neurocognitive disorders
Q27490236Complement and its role in protection and pathogenesis of flavivirus infections
Q37055637Complement-HIV interactions during all steps of viral pathogenesis.
Q38673539Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir.
Q33955105Differential activity of candidate microbicides against early steps of HIV-1 infection upon complement virus opsonization
Q36090335Evasion and interactions of the humoral innate immune response in pathogen invasion, autoimmune disease, and cancer
Q41741684Functions of Antibodies.
Q40657302Glycosylphosphatidylinositol Anchor Deficiency Attenuates the Production of Infectious HIV-1 and Renders Virions Sensitive to Complement Attack
Q30248405HIV-1 and hijacking of the host immune system: the current scenario
Q36827324Hepatitis C virus suppresses C9 complement synthesis and impairs membrane attack complex function
Q33742139Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary
Q38139934Innate immune evasion strategies by human immunodeficiency virus type 1.
Q50116524Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages
Q34039343NF-κB and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack
Q85097634Paroxysmal nocturnal hemoglobinuria clones are not present in HIV positive patients
Q34218827Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells
Q41413269Role of complement and Fc receptors in the pathogenesis of HIV-1 infection
Q35134722Role of complement in the control of HIV dynamics and pathogenesis
Q35976953The Trojan exosome hypothesis
Q28275986The good and evil of complement activation in HIV-1 infection
Q33688595Viral complement regulatory proteins
Q35122624Viral mimicry of the complement system

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