A rapid in vitro assay for HIV DNA integration

scientific article published on May 1991

A rapid in vitro assay for HIV DNA integration is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/19.10.2729
P932PMC publication ID328193
P698PubMed publication ID2041748
P5875ResearchGate publication ID21113762

P2093author name stringMizuuchi K
Bushman FD
Craigie R
Engelman A
P2860cites workThe IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitroQ45851069
The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.Q54707474
Stoichiometric use of the transposase of bacteriophage MuQ70183891
Molecular targets for AIDS therapyQ28323494
Retroviral DNA integration directed by HIV integration protein in vitroQ28646770
Integration of human immunodeficiency virus type 1 DNA in vitroQ33608319
Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activityQ33666234
Genetic recombination of human immunodeficiency virusQ36782092
Removal of 3'-OH-terminal nucleotides from blunt-ended long terminal repeat termini by the avian retrovirus integration proteinQ36793581
Human immunodeficiency virus integration in a cell-free systemQ36807041
The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integrationQ36832318
Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNAQ37402258
Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymesQ37402708
Unraveling retrovirus integrationQ38137897
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)2729-2734
P577publication date1991-05-01
P1433published inNucleic Acids ResearchQ135122
P1476titleA rapid in vitro assay for HIV DNA integration
P478volume19

Reverse relations

cites work (P2860)
Q40969466A high-throughput assay for Tn5 Tnp-induced DNA cleavage
Q40400122A high-throughput, non-radioactive microtiter plate assay for activity of the human immunodeficiency virus integrase protein
Q38359623A molecular mechanics and dynamics study of alternate triple-helices involving the integrase-binding site of the HIV-1 virus and oligonucleotides having a 3'-3' internucleotide junction
Q33502482A nonradioactive plate-based assay for stimulators of nonspecific DNA nicking by HIV-1 integrase and other nucleases
Q73789114A rapid and quantitative assay for inhibition of 3' cleavage activity of HIV-1 integrase
Q38916846A review on architecture of the gag-pol ribosomal frameshifting RNA in human immunodeficiency virus: a variability survey of virus genotypes
Q38358758Alternate strand DNA triple helix-mediated inhibition of HIV-1 U5 long terminal repeat integration in vitro
Q36666299Architecture and assembly of HIV integrase multimers in the absence of DNA substrates
Q33838063Biochemical and pharmacological analyses of HIV-1 integrase flexible loop mutants resistant to raltegravir
Q38318959Branched oligonucleotide-intercalator conjugate forming a parallel stranded structure inhibits HIV-1 integrase
Q37281481Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution
Q37139736Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants
Q46652865Development and application of a high-throughput screening assay for HIV-1 integrase enzyme activities.
Q36672092Discovery and in vitro development of AIDS antiviral drugs as biopharmaceuticals
Q35077531Expression and partial purification of enzymatically active recombinant Ty1 integrase in Saccharomyces cerevisiae
Q40522224Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.
Q30407372HIV virions as nanoscopic test tubes for probing oligomerization of the integrase enzyme.
Q38348637HIV-1 integrase and virus and cell DNAs: complex formation and perturbation by inhibitors of integration
Q34050694HIV-1 integrase inhibitors: past, present, and future
Q37034614HIV-1 integrase inhibitors: update and perspectives
Q38295884HIV-1 preintegration complexes preferentially integrate into longer target DNA molecules in solution as detected by a sensitive, polymerase chain reaction-based integration assay
Q33221506Homogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities
Q40065873Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions
Q28379456Identification of a nucleotide binding site in HIV-1 integrase
Q34764444Incorporation of a fluorescent guanosine analog into oligonucleotides and its application to a real time assay for the HIV-1 integrase 3'-processing reaction
Q39352071Inhibiting the HIV integration process: past, present, and the future.
Q40391827Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds
Q44665762Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides
Q28369221Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate
Q33929260Inhibition of the integrase of human immunodeficiency virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31
Q28378683Inhibitors of human immunodeficiency virus integrase
Q33671224Inhibitors of human immunodeficiency virus integrase.
Q34397376Integrase inhibitors to treat HIV/AIDS.
Q39783580Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins
Q40295190Measurement of In Vitro Integration Activity of HIV-1 Preintegration Complexes.
Q41963850Mechanistic and pharmacological analyses of HIV-1 integration
Q34437364Metal binding by the D,DX35E motif of human immunodeficiency virus type 1 integrase: selective rescue of Cys substitutions by Mn2+ in vitro
Q46545766Monitoring the HIV-1 integrase enzymatic activity using atomic force microscopy in a 2LTR system
Q92992903Multifaceted HIV integrase functionalities and therapeutic strategies for their inhibition
Q27678745New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action
Q37325980Oligonucleotide-based assays for integrase activity
Q33398037Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration
Q24316120Peptides that bind the HIV-1 integrase and modulate its enzymatic activity--kinetic studies and mode of action
Q40486948Present Status and Future Prospects for HIV Therapies
Q36587864Proteomic analysis of early HIV-1 nucleoprotein complexes
Q30635816Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation
Q36717795Rapid solution assays for retroviral integration reactions and their use in kinetic analyses of wild-type and mutant Rous sarcoma virus integrases
Q35952270Repair of transposable phage Mu DNA insertions begins only when the E. coli replisome collides with the transpososome
Q34059896Resistance to integrase inhibitors
Q34643561Retroviral integrase proteins and HIV-1 DNA integration
Q36723801Role of integrase inhibitors in the treatment of HIV disease
Q38349833Specificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase {alpha}4 helix
Q38307527Substrate features important for recognition and catalysis by human immunodeficiency virus type 1 integrase identified by using novel DNA substrates
Q35050390Targeting HIV-1 integrase
Q36581635The Mu story: how a maverick phage moved the field forward
Q40393204Therapy Other Than Reverse Transcriptase Inhibitors for HIV Infection
Q28369657Triterpene derivatives that block entry of human immunodeficiency virus type 1 into cells
Q40762611Viral gene products and replication of the human immunodeficiency type 1 virus

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