Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycans

scientific article published on January 2012

Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1369/0022155411428469
P932PMC publication ID3283135
P698PubMed publication ID22205677
P5875ResearchGate publication ID51969967

P2093author name stringJohn R Couchman
Hinke A B Multhaupt
Atsuko Yoneda
Maria E Lendorf
P2860cites workGlypicansQ21183908
Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinomaQ73144573
High syndecan-1 expression is associated with favourable outcome in squamous cell lung carcinoma treated with radical surgeryQ73965564
Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in miceQ73977149
Glypican-3 expression in primary and recurrent ovarian carcinomasQ80506061
Oncofetal protein glypican-3 distinguishes yolk sac tumor from clear cell carcinoma of the ovaryQ80709350
Syndecan-1 and syndecan-4 are overexpressed in an estrogen receptor-negative, highly proliferative breast carcinoma subtypeQ83198017
Ovarian cancerQ84605146
Syndecan-2 regulates cell migration in colon cancer cells through Tiam1-mediated Rac activationQ84984670
Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndromeQ24320198
Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancerQ24550887
Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion componentQ24621174
Heparan sulphate synthetic and editing enzymes in ovarian cancerQ24653774
Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4Q24681644
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsQ27860709
Molecular portraits of human breast tumoursQ28032461
Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cellsQ28206492
Solution Structure of a Syndecan-4 Cytoplasmic Domain and Its Interaction with Phosphatidylinositol 4,5-BisphosphateQ28270480
Distribution and clinical significance of heparan sulfate proteoglycans in ovarian cancerQ28275904
Heparan Sulfate Proteoglycans as Regulators of Fibroblast Growth Factor-2 Receptor Binding in Breast CarcinomasQ28344801
Control of morphology, cytoskeleton and migration by syndecan-4Q28568063
The loss of glypican-3 induces alterations in Wnt signalingQ28575434
Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog bindingQ28590274
Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4Q28591320
Cancer statistics, 2009Q29547625
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Oncogenic pathway signatures in human cancers as a guide to targeted therapiesQ29615526
Genomic and transcriptional aberrations linked to breast cancer pathophysiologiesQ29619120
Heparan sulphate proteoglycans fine-tune mammalian physiologyQ29619329
Order out of chaos: assembly of ligand binding sites in heparan sulfateQ29620085
Transmembrane signaling proteoglycansQ30390527
Epithelial syndecan-1 expression is associated with stage and grade in colorectal cancerQ33219573
ABC of breast diseases: breast cancerQ33818080
Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancerQ33845160
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Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signalingQ34294737
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Protein kinase C regulates the recruitment of syndecan-4 into focal contactsQ34452929
Loss of heterozygosity on chromosome XP22.2-p22.13 and Xq26.1-q27.1 in human breast carcinomasQ34656153
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Progesterone receptor by immunohistochemistry and clinical outcome in breast cancer: a validation studyQ38446888
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Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cellsQ40297851
Syndecan recycling [corrected] is controlled by syntenin-PIP2 interaction and Arf6.Q40378604
Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling.Q40413283
OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2.Q41120310
Estradiol-estrogen receptor: a key interplay of the expression of syndecan-2 and metalloproteinase-9 in breast cancer cellsQ41129821
Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movementsQ41871371
Syndecan-4 regulates localization, activity and stability of protein kinase C-alphaQ42156901
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancerQ42499457
Glypican-3 expression predicts poor clinical outcome of patients with early-stage clear cell carcinoma of the ovaryQ42849233
Prophylactic bilateral salpingo-oophorectomy compared with surveillance in women with BRCA mutations.Q43424801
Reduced Expression of Syndecan‐1 Affects Metastatic Potential and Clinical Outcome in Patients with Colorectal CancerQ43777017
Glypican-3 expression is silenced in human breast cancerQ43796931
Inhibition of invasion and metastasis by glypican-3 in a syngeneic breast cancer model.Q43872108
Glypican-3 expression in clear cell adenocarcinoma of the ovaryQ44268931
Relationship between long durations and different regimens of hormone therapy and risk of breast cancerQ44489759
A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase.Q44816865
Epidemiology and risk assessment for ovarian cancerQ45142084
Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activityQ47070543
Dissecting complex epigenetic alterations in breast cancer using CpG island microarraysQ51602472
Heparan sulfate proteoglycans at a glanceQ51985397
Loss of cell-surface heparan sulfate expression in both cervical intraepithelial neoplasm and invasive cervical cancerQ53359239
A clinicopathologic analysis of atypical proliferative (borderline) tumors and well-differentiated endometrioid adenocarcinomas of the ovaryQ53404100
Syndecan-2 mediates adhesion and proliferation of colon carcinoma cellsQ53669222
High performance capillary electrophoresis method to characterize heparin and heparan sulfate disaccharidesQ71744256
Syndecan-1 and syndecan-4 are independent indicators in breast carcinomaQ35441324
Syndecans: proteoglycan regulators of cell-surface microdomains?Q35611355
Breast cancer biomarkers and molecular medicine: part II.Q35680309
Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrixQ35828567
Functions of heparan sulfate proteoglycans in cell signaling during developmentQ35962679
Utilizing prognostic and predictive factors in breast cancerQ36046256
Origins and molecular pathology of ovarian cancerQ36068263
Significance of Heparanase in Cancer and InflammationQ36101233
The etiology of alcohol-induced breast cancerQ36213159
OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner.Q36255453
Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cellsQ36321055
Breast cancer biomarkers.Q36342545
Diagnosis and management of epithelial ovarian cancerQ36493937
Molecular pathology of epithelial ovarian cancerQ36507679
Interactions between heparan sulfate and proteins: the concept of specificityQ36552851
Extracellular matrix of ovarian tumors.Q36582459
Transmembrane domains of the syndecan family of growth factor coreceptors display a hierarchy of homotypic and heterotypic interactionsQ36696352
Early detection and treatment of ovarian cancer: shifting from early stage to minimal volume of disease based on a new model of carcinogenesisQ36868408
Molecular subtyping of breast cancer: opportunities for new therapeutic approachesQ36980338
Synergistic control of cell adhesion by integrins and syndecans.Q36986535
Syndecan-1: a dynamic regulator of the myeloma microenvironmentQ37008599
Predictive markers in breast cancer--the presentQ37048779
The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation.Q37228526
Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion.Q37475741
Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis.Q37494563
Interactions between heparan sulfate and proteins-design and functional implicationsQ37543699
Chapter 1. Focal adhesions: new angles on an old structure.Q37600445
Syndecan signaling: when, where and why?Q37677440
Issues and updates: evaluating estrogen receptor-alpha, progesterone receptor, and HER2 in breast cancerQ37740951
Sulf-2: an extracellular modulator of cell signaling and a cancer target candidateQ37772524
Proteoglycans in health and disease: the multiple roles of syndecan sheddingQ37788814
Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting.Q37788815
The heparanase system and tumor metastasis: is heparanase the seed and soil?Q37838802
Ovarian Cancer Management: the role of imaging and diagnostic challenges.Q37851707
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
heparan sulfate proteoglycansQ66589633
P304page(s)9-21
P577publication date2012-01-01
P1433published inJournal of Histochemistry and CytochemistryQ1523992
P1476titleBreast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycans
P478volume60

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