Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region

scientific article published on August 1991

Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/19.15.4139
P932PMC publication ID328553
P698PubMed publication ID1870969
P5875ResearchGate publication ID21284954

P2093author name stringR H Costa
D R Grayson
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A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genesQ33577523
Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promotersQ33660554
Site-directed mutagenesis reveals a liver transcription factor essential for the albumin transcriptional enhancerQ33697085
Similarities in transthyretin gene expression and differences in transcription factors: liver and yolk sac compared to choroid plexusQ33761691
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Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic miceQ33918459
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Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1.Q36761748
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genesQ36763447
The cell-specific enhancer of the mouse transthyretin (prealbumin) gene binds a common factor at one site and a liver-specific factor(s) at two other sitesQ36779415
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Pattern of serum protein gene expression in mouse visceral yolk sac and foetal liverQ41578122
The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domainQ42642911
Rapid in vivo footprinting technique identifies proteins bound to the TTR gene in the mouse liverQ44239026
The interplay of DNA-binding proteins on the promoter of the mouse albumin geneQ48170138
Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork headQ48232472
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Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.Q52245350
Mechanism of action of a yeast activator: Direct effect of GAL4 derivatives on mammalian TFIID-promoter interactionsQ58422728
Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chainsQ64379836
One factor recognizes the liver-specific enhancers in alpha 1-antitrypsin and transthyretin genesQ68090793
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P433issue15
P407language of work or nameEnglishQ1860
P304page(s)4139-4145
P577publication date1991-08-01
P1433published inNucleic Acids ResearchQ135122
P1476titleSite-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region
P478volume19