scholarly article | Q13442814 |
P50 | author | Gordon X Wang | Q91776865 |
P2093 | author name string | Stephen J Smith | |
Philippe Mourrain | |||
P2860 | cites work | Mechanism-based approaches to treating fragile X | Q22251222 |
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NEURONAL CIRCUITS OF THE NEOCORTEX | Q22337027 | ||
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Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P | Q24531856 | ||
Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex | Q24554385 | ||
mTOR signaling: at the crossroads of plasticity, memory and disease | Q24647655 | ||
A pilot open label, single dose trial of fenobam in adults with fragile X syndrome. | Q24654933 | ||
Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits | Q24657867 | ||
Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation syndrome | Q48337615 | ||
Potentiation of cortical inhibition by visual deprivation. | Q48438986 | ||
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice. | Q48569575 | ||
Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome. | Q48663468 | ||
Short- and long-term depression at glutamatergic synapses on hippocampal interneurons by group I mGluR activation. | Q48942540 | ||
Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins. | Q50303922 | ||
A phenotypic and molecular characterization of the fmr1-tm1Cgr fragile X mouse. | Q50307286 | ||
Developmental trajectories and correlates of sensory processing in young boys with fragile X syndrome. | Q51892070 | ||
Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome. | Q51930328 | ||
Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse. | Q51932364 | ||
Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression | Q60141744 | ||
Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial | Q85000324 | ||
Synapses and Alzheimer's disease | Q26269868 | ||
Deep molecular diversity of mammalian synapses: why it matters and how to measure it | Q26998700 | ||
The pathophysiology of fragile X (and what it teaches us about synapses) | Q27010675 | ||
Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2 | Q27665857 | ||
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome | Q28273791 | ||
PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses | Q28288026 | ||
Threats to validity in the design and conduct of preclinical efficacy studies: a systematic review of guidelines for in vivo animal experiments | Q28534767 | ||
The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits | Q28588310 | ||
Abnormal development of dendritic spines in FMR1 knock-out mice | Q28589950 | ||
Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity | Q28591445 | ||
The evolution of the brain, the human nature of cortical circuits, and intellectual creativity | Q28744426 | ||
Morphological changes in dendritic spines associated with long-term synaptic plasticity | Q29614372 | ||
Structure and function of dendritic spines | Q29617057 | ||
Molecular mechanisms of dendritic spine morphogenesis | Q29903592 | ||
VGluT2 immunochemistry identifies thalamocortical terminals in layer 4 of adult and developing visual cortex | Q30436278 | ||
Organization of the core structure of the postsynaptic density | Q30482020 | ||
Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice | Q30488610 | ||
Long-term sensory deprivation selectively rearranges functional inhibitory circuits in mouse barrel cortex. | Q30488660 | ||
Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome | Q30537599 | ||
Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits | Q33289933 | ||
An anatomical substrate for experience-dependent plasticity of the rat barrel field cortex | Q33727555 | ||
Extracellular-signal-regulated kinase signalling in neurons | Q33745304 | ||
Actin-associated protein synaptopodin in the rat hippocampal formation: localization in the spine neck and close association with the spine apparatus of principal neurons | Q33892141 | ||
Synaptic efficacy and reliability of excitatory connections between the principal neurones of the input (layer 4) and output layer (layer 5) of the neocortex | Q33919102 | ||
Region-specific alterations in brain development in one- to three-year-old boys with fragile X syndrome | Q33927318 | ||
The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. | Q33930416 | ||
Delayed stabilization of dendritic spines in fragile X mice | Q33991423 | ||
Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome | Q34003224 | ||
Glutamate induces the elongation of early dendritic protrusions via mGluRs in wild type mice, but not in fragile X mice | Q34182716 | ||
Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers | Q34371962 | ||
Sub-diffraction limit localization of proteins in volumetric space using Bayesian restoration of fluorescence images from ultrathin specimens | Q34407768 | ||
Homeostatic scaling requires group I mGluR activation mediated by Homer1a | Q34455735 | ||
Extracellular signal-regulated kinase, synaptic plasticity, and memory | Q34488393 | ||
Complementary distribution of vesicular glutamate transporters in the central nervous system | Q34621675 | ||
Environmental enrichment reveals effects of genotype on hippocampal spine morphologies in the mouse model of Fragile X Syndrome. | Q35003579 | ||
Mutations causing syndromic autism define an axis of synaptic pathophysiology | Q35587150 | ||
GABA system dysfunction in autism and related disorders: from synapse to symptoms | Q35770888 | ||
Dendritic spines and long-term plasticity | Q36085643 | ||
Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes | Q36208140 | ||
The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments in Fmr1 KO mice. | Q36379639 | ||
Dysregulation of mTOR signaling in fragile X syndrome | Q36879282 | ||
Mapping functional connectivity in barrel-related columns reveals layer- and cell type-specific microcircuits | Q36918706 | ||
Excitatory signal flow and connectivity in a cortical column: focus on barrel cortex | Q36918710 | ||
Imbalance of neocortical excitation and inhibition and altered UP states reflect network hyperexcitability in the mouse model of fragile X syndrome | Q36978553 | ||
Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome | Q37059491 | ||
Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models | Q37190453 | ||
Differential distribution of endoplasmic reticulum controls metabotropic signaling and plasticity at hippocampal synapses | Q37329645 | ||
mGluR5 regulates glutamate-dependent development of the mouse somatosensory cortex | Q37352265 | ||
Metabotropic glutamate receptor-dependent long-term potentiation | Q37586419 | ||
Stimulated emission depletion (STED) microscopy reveals nanoscale defects in the developmental trajectory of dendritic spine morphogenesis in a mouse model of fragile X syndrome. | Q37732667 | ||
The spine apparatus, synaptopodin, and dendritic spine plasticity | Q37733207 | ||
Long-range connectivity of mouse primary somatosensory barrel cortex | Q37765313 | ||
Contributions of ERK signaling in the striatum to instrumental learning and performance. | Q37819314 | ||
Dendritic mRNA targeting and translation | Q37986661 | ||
Intercellular (mis)communication in neurodegenerative disease. | Q37992251 | ||
Synaptopathies: diseases of the synaptome. | Q37992734 | ||
Evolution of synapse complexity and diversity | Q38020190 | ||
Alzheimer's disease drug development: translational neuroscience strategies | Q38087640 | ||
Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions | Q38947125 | ||
The expression of vesicular glutamate transporters defines two classes of excitatory synapse | Q39750117 | ||
The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons. | Q40769813 | ||
Absence of expression of the FMR-1 gene in fragile X syndrome | Q41669091 | ||
Differential impact of the FMR1 gene on visual processing in fragile X syndrome | Q42455947 | ||
Characterization of the proteome, diseases and evolution of the human postsynaptic density. | Q42610204 | ||
Deep cortical layers are activated directly by thalamus | Q42952158 | ||
Early developmental alterations in GABAergic protein expression in fragile X knockout mice | Q43063055 | ||
Synaptic plasticity in the adult visual cortex is regulated by the metabotropic glutamate receptor, mGluR5. | Q43293591 | ||
Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1. | Q44902343 | ||
Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex | Q45041368 | ||
Vesicular glutamate transporters define two sets of glutamatergic afferents to the somatosensory thalamus and two thalamocortical projections in the mouse | Q46053391 | ||
Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons. | Q46142239 | ||
Expression of the GABAergic system in animal models for fragile X syndrome and fragile X associated tremor/ataxia syndrome (FXTAS). | Q46205774 | ||
Postnatal changes of vesicular glutamate transporter (VGluT)1 and VGluT2 immunoreactivities and their colocalization in the mouse forebrain | Q46746316 | ||
Homer 1a suppresses neocortex long-term depression in a cortical layer-specific manner. | Q46852243 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1273-1286 | |
P577 | publication date | 2014-12-01 | |
P1433 | published in | Neuron | Q3338676 |
P1476 | title | Fmr1 KO and fenobam treatment differentially impact distinct synapse populations of mouse neocortex | |
P478 | volume | 84 |
Q47134754 | Altered Developmental Expression of the Astrocyte-Secreted Factors Hevin and SPARC in the Fragile X Mouse Model |
Q26796317 | Altered Neuronal and Circuit Excitability in Fragile X Syndrome. |
Q90911156 | Altered dendritic spine function and integration in a mouse model of fragile X syndrome |
Q37019183 | Effects of Chronic Sleep Restriction during Early Adolescence on the Adult Pattern of Connectivity of Mouse Secondary Motor Cortex. |
Q28551350 | Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish |
Q50573783 | GABAB receptor-mediated feed-forward circuit dysfunction in the mouse model of fragile X syndrome. |
Q38678066 | Genetic and Pharmacological Reversibility of Phenotypes in Mouse Models of Autism Spectrum Disorder |
Q90288224 | Multifaceted Changes in Synaptic Composition and Astrocytic Involvement in a Mouse Model of Fragile X Syndrome |
Q58801747 | Regulation of IL-6 Secretion by Astrocytes via TLR4 in the Fragile X Mouse Model |
Q37398536 | Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in Fmr1 KO synapses |
Q92201725 | Synapse diversity and synaptome architecture in human genetic disorders |
Q27023257 | Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes |
Q27337360 | Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back |
Q36373809 | Unbiased, High-Throughput Electron Microscopy Analysis of Experience-Dependent Synaptic Changes in the Neocortex |
Q35867117 | mGluR5 Positive and Negative Allosteric Modulators Differentially Affect Dendritic Spine Density and Morphology in the Prefrontal Cortex |
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