Tissue-engineered models of human tumors for cancer research

scientific article published on 7 February 2015

Tissue-engineered models of human tumors for cancer research is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1517/17460441.2015.1009442
P932PMC publication ID4479424
P698PubMed publication ID25662589
P5875ResearchGate publication ID272098540

P50authorGordana Vunjak-NovakovicQ54394
Aranzazu VillasanteQ43151931
P2860cites workThe enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugsQ39444152
Development of an in vitro model to study the impact of BMP-2 on metastasis to boneQ39652024
Engineering tumors with 3D scaffoldsQ40085983
The development of a functionally relevant cell culture model of progressive human breast cancer.Q40380924
Multi-faceted regulation of cell differentiation by extracellular matrix.Q40824976
Optimizing the medium perfusion rate in bone tissue engineering bioreactorsQ41820368
Transplantation of cancerous cell sheets effectively generates tumour-bearing model miceQ42456360
Growth of nodular carcinomas in rodents compared with multi-cell spheroids in tissue cultureQ43863839
Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfacesQ43893196
Differences in Patterns of Aggregation of Malignant and Non-Malignant Mammalian CellsQ58975034
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's EpitheliumQ63406947
Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fibronectin matrix from temperature-responsive culture surfacesQ77733896
Can animal models of disease reliably inform human studies?Q21563449
Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer modelsQ27304708
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cellsQ28204395
Putting tumours in contextQ28207789
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesisQ28279053
Ex-vivo dynamic 3-D culture of human tissues in the RCCS™ bioreactor allows the study of Multiple Myeloma biology and response to therapyQ28535634
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesisQ29547178
Osteoclast differentiation and activationQ29547556
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytesQ29547633
Genomic responses in mouse models poorly mimic human inflammatory diseasesQ29547718
The Ink4/Arf locus is a barrier for iPS cell reprogrammingQ29614210
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progressionQ29614274
The distribution of secondary growths in cancer of the breast. 1889Q29614314
Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.Q30355361
Engineered microenvironments for controlled stem cell differentiationQ30488054
Three-dimensional culture models of normal and malignant breast epithelial cellsQ30496418
Collective invasion in breast cancer requires a conserved basal epithelial programQ30573307
All-human microphysical model of metastasis therapyQ33641654
A three-dimensional in vitro model of tumor cell intravasationQ33716526
Engineering anatomically shaped human bone graftsQ33734739
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid cultureQ33865017
Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.Q33953572
Cultivation of human bone-like tissue from pluripotent stem cell-derived osteogenic progenitors in perfusion bioreactorsQ33992658
Osteomimicry: how tumor cells try to deceive the boneQ34022631
Prostate cancer xenografts engineered from 3D precision-porous poly(2-hydroxyethyl methacrylate) hydrogels as models for tumorigenesis and dormancy escapeQ34053377
In vitro model of vascularized bone: synergizing vascular development and osteogenesisQ34099206
Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tensionQ34221060
The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancerQ34291977
Integrating macrophages into organotypic co-cultures: a 3D in vitro model to study tumor-associated macrophagesQ34335849
Organoid cultures derived from patients with advanced prostate cancerQ34545103
Modeling tissue morphogenesis and cancer in 3D.Q34667330
Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancerQ34795002
Novel 3D co-culture model for epithelial-stromal cells interaction in prostate cancerQ35000828
Control of osteoblast function and regulation of bone massQ35128237
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.Q35813751
Osteoblasts in prostate cancer metastasis to boneQ35998759
Engineering bone tissue from human embryonic stem cellsQ36001194
A microphysiological system model of therapy for liver micrometastasesQ36072561
Engineering approaches for investigating tumor angiogenesis: exploiting the role of the extracellular matrixQ36442261
Empirical chemosensitivity testing in a spheroid model of ovarian cancer using a microfluidics-based multiplex platformQ36564821
Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytesQ36610161
Life isn't flat: taking cancer biology to the next dimensionQ36681269
Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biologyQ36755844
Modeling Ewing sarcoma tumors in vitro with 3D scaffoldsQ36782138
Three-dimensional cultures of mouse mammary epithelial cellsQ36883681
Engineering bone tissue substitutes from human induced pluripotent stem cellsQ36884199
Cancer to bone: a fatal attractionQ36884628
The Interplay between the bone and the immune systemQ37052226
Biomimetic approach to tissue engineeringQ37261143
Effects of initial seeding density and fluid perfusion rate on formation of tissue-engineered boneQ37411849
A three-dimensional osteogenic tissue model for the study of metastatic tumor cell interactions with bone.Q37478795
Contributions of the host microenvironment to cancer-induced bone disease.Q37663962
Multicellular tumor spheroids: an underestimated tool is catching up again.Q37680413
3D tumour models: novel in vitro approaches to cancer studiesQ37866146
Calcium in tumour metastasis: new roles for known actors.Q37903657
In vitro three-dimensional (3D) models in cancer research: an updateQ37967634
Modeling the tumor extracellular matrix: Tissue engineering tools repurposed towards new frontiers in cancer biologyQ38168344
Perfused multiwell plate for 3D liver tissue engineeringQ38590052
Inhibition of macrophage polarization prohibits growth of human osteosarcomaQ38998216
Bioengineered human tumor within a bone nicheQ39002897
Paracrine interactions between LNCaP prostate cancer cells and bioengineered bone in 3D in vitro culture reflect molecular changes during bone metastasisQ39023576
Porous chitosan-hyaluronic acid scaffolds as a mimic of glioblastoma microenvironment ECM.Q39090430
PDMS well platform for culturing millimeter-size tumor spheroidsQ39129146
Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer.Q39269339
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)257-268
P577publication date2015-02-07
P1433published inExpert Opinion on Drug DiscoveryQ5421204
P1476titleTissue-engineered models of human tumors for cancer research
P478volume10