Hibernomas are characterized by homozygous deletions in the multiple endocrine neoplasia type I region. Metaphase fluorescence in situ hybridization reveals complex rearrangements not detected by conventional cytogenetics

scientific article published on July 1999

Hibernomas are characterized by homozygous deletions in the multiple endocrine neoplasia type I region. Metaphase fluorescence in situ hybridization reveals complex rearrangements not detected by conventional cytogenetics is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0002-9440(10)65099-7
P932PMC publication ID1866650
P698PubMed publication ID10393837

P50authorFredrik MertensQ38640082
Mattias HöglundQ40511373
P2093author name stringN Mandahl
D Gisselsson
P Dal Cin
P2860cites workThe germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13Q24320163
Construction of a 1.2-Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.Q34438169
Correlation between clinicopathological features and karyotype in lipomatous tumors. A report of 178 cases from the Chromosomes and Morphology (CHAMP) Collaborative Study GroupQ34732634
Hibernoma development in transgenic mice identifies brown adipose tissue as a novel target of aldosterone action.Q37379344
Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type 1-associated and sporadic gastrinomas and pancreatic endocrine tumorsQ38474599
Chromosomal organization of amplified chromosome 12 sequences in mesenchymal tumors detected by fluorescence in situ hybridizationQ38501694
Band 11q13 is nonrandomly rearranged in hibernomasQ40388578
Deletion mapping of endocrine tumors localizes a second tumor suppressor gene on chromosome band 11q13.Q46229550
A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13.Q48048567
Melatonin stimulates Growth of Brown Adipose TissueQ59062824
Chromosome changes in a case of hibernomaQ67542550
Endocrine activity in a large hibernomaQ71102004
Allelic losses on chromosome band 11q13 in aldosterone-producing adrenal tumorsQ71680255
Hibernomas are characterized by rearrangements of chromosome bands 11q13-21Q72120291
Involvement of 10q22 and 11q13 in hibernomaQ72250909
Molecular characterization of a recurring complex chromosomal translocation in two human extragonadal germ cell tumorsQ72399670
Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1Q73543135
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcytogeneticsQ246128
multiple endocrine neoplasiaQ1553018
homozygosityQ114049690
P304page(s)61-66
P577publication date1999-07-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleHibernomas are characterized by homozygous deletions in the multiple endocrine neoplasia type I region. Metaphase fluorescence in situ hybridization reveals complex rearrangements not detected by conventional cytogenetics
P478volume155

Reverse relations

cites work (P2860)
Q7351070411q13 alterations in two cases of hibernoma: large heterozygous deletions and rearrangement breakpoints near GARP in 11q13.5.
Q33996416C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma
Q34397427Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma
Q37832955Contributions of cytogenetics and molecular cytogenetics to the diagnosis of adipocytic tumors
Q74719617Determination of allelic deletion of multiple endocrine neoplasm type 1 (MEN1) gene in acute myeloid leukemia (AML) by application of FISH-TSA technique
Q36803632Gene translocations in musculoskeletal neoplasms
Q34305740MEN1 Syndrome and Hibernoma: An Uncommonly Recognised Association?
Q37385364Mediastinal lipoblastomatosis: report of a case with complex karyotype and review of the literature
Q51830527Reverse referral: from pathology to endocrinology.
Q37577701The benefits of molecular pathology in the diagnosis of musculoskeletal disease : part I of a two-part review: soft tissue tumors
Q36344267The role of genetic testing in soft tissue sarcoma
Q53087549Well-Differentiated Liposarcoma With Hibernoma-Like Morphology.
Q77881937[Hibernoma: a rare case of massive weight loss]