The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity

scientific article published on April 2004

The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S00109-004-0529-0
P698PubMed publication ID15168680
P5875ResearchGate publication ID8537392

P2093author name stringSandra L Wolin
Xinguo Chen
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
Lateral gene transfer and the nature of bacterial innovationQ22122396
Initial sequencing and comparative analysis of the mouse genomeQ22122521
A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomesQ24290780
A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP proteinQ24293251
Molecular analysis of the 60-kDa human Ro ribonucleoproteinQ24297302
Comparative genomics and evolution of proteins involved in RNA metabolismQ24515041
Conserved features of Y RNAs: a comparison of experimentally derived secondary structuresQ24515322
Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhereQ24537227
Binding of the 60-kDa Ro autoantigen to Y RNAs: evidence for recognition in the major groove of a conserved helix.Q24539238
PUF60: a novel U2AF65-related splicing activityQ24539523
Interaction cloning and characterization of RoBPI, a novel protein binding to human Ro ribonucleoproteinsQ24539578
Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodiesQ24562717
Ro ribonucleoproteins contribute to the resistance of Deinococcus radiodurans to ultraviolet irradiationQ24607590
Complete genome sequence of the marine planctomycete Pirellula sp. strain 1Q24679932
The TROVE module: a common element in Telomerase, Ro and Vault ribonucleoproteinsQ24793277
The FBP interacting repressor targets TFIIH to inhibit activated transcriptionQ28140020
Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivoQ28140790
Analysis of the molecular composition of Ro ribonucleoprotein complexes. Identification of novel Y RNA-binding proteinsQ28143106
Origins of highly mosaic mycobacteriophage genomesQ28198119
The La proteinQ28202309
Nucleolin associates with a subset of the human Ro ribonucleoprotein complexesQ28208632
RNA-binding proteins as developmental regulatorsQ28237577
Two Novel Classes of Small Ribonucleoproteins Detected by Antibodies Associated with Lupus ErythematosusQ28262006
The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAsQ28262911
Human 60-kDa SS-A/Ro ribonucleoprotein autoantigen gene (SSA2) localized to 1q31 by fluorescence in situ hybridizationQ28305875
The Ro autoantigen binds misfolded U2 small nuclear RNAs and assists mammalian cell survival after UV irradiationQ28505483
A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigenQ28507498
A mammalian telomerase-associated proteinQ28595030
Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigreesQ28776419
Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biologyQ29618865
Cutaneous lupus erythematosus: a reviewQ30309818
Tetrahymena proteins p80 and p95 are not core telomerase componentsQ30453860
Neonatal lupus: clinical features, therapy, and pathogenesisQ33339032
Phagocytosis and clearance of apoptotic cells is mediated by MER.Q33946282
Molecular composition of Ro small ribonucleoprotein complexes in human cells. Intracellular localization of the 60- and 52-kD proteinsQ34140125
A major susceptibility locus for systemic lupus erythemathosus maps to chromosome 1q31Q34153866
Quality control of mRNA functionQ34156109
Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degenerationQ34205369
Autoantibodies in the diagnosis of systemicrheumatic diseasesQ34299389
Delineating the genetic basis of systemic lupus erythematosusQ34376876
The levels of the RoRNP-associated Y RNA are dependent upon the presence of ROP-1, the Caenorhabditis elegans Ro60 proteinQ34606099
Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytesQ34618445
Vault ribonucleoprotein particles: sarcophagi, gondolas, or safety deposit boxes?Q35015678
Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiationQ35822538
A 52-kD protein is a novel component of the SS-A/Ro antigenic particleQ36354952
Xenopus Ro ribonucleoproteins: members of an evolutionarily conserved class of cytoplasmic ribonucleoproteinsQ36458572
Characterization of human telomerase complex.Q36581467
Ro RNP associated Y RNAs are highly conserved among mammalsQ36673415
Ro Small Cytoplasmic Ribonucleoproteins Are a Subclass of La Ribonucleoproteins: Further Characterization of the Ro and La Small Ribonucleoproteins from Uninfected Mammalian CellsQ36970019
Clinical and serological differences between systemic lupus erythematosus patients with antibodies to Ro versus patients with antibodies to Ro and La.Q36982346
ROP-1, an RNA quality-control pathway component, affects Caenorhabditis elegans dauer formationQ37289169
The heterogeneous nuclear ribonucleoproteins I and K interact with a subset of the ro ribonucleoprotein-associated Y RNAs in vitro and in vivo.Q38302460
Conserved features of Y RNAs revealed by automated phylogenetic secondary structure analysisQ39727265
Ultraviolet Light Effects on the Bacterial CellQ39977215
Common structural features of the Ro RNP associated hY1 and hY5 RNAs.Q40400394
Analysis of protein--RNA interactions within Ro ribonucleoprotein complexesQ40507411
In vivo cell penetration and intracellular transport of anti-Sm and anti-La autoantibodiesQ40890173
Mercury-induced anti-nucleolar autoantibodies can transgress the membrane of living cells in vivo and in vitro.Q40954865
Significance of the anti-Ro (SS-A) antibody in evaluation of patients with cutaneous manifestations of a connective tissue diseaseQ41033561
The lupus autoantigens and the pathogenesis of systemic lupus erythematosusQ41355812
A subgroup of murine monoclonal anti-deoxyribonucleic acid antibodies traverse the cytoplasm and enter the nucleus in a time-and temperature- dependent manner.Q41456439
Subcellular distribution of Ro ribonucleoprotein complexes and their constituents.Q41519429
Penetration of autoantibodies into living epithelial cellsQ41569934
Analysis of the intracellular localization and assembly of Ro ribonucleoprotein particles by microinjection into Xenopus laevis oocytesQ41882450
The Caenorhabditis elegans rop-1 gene encodes the homologue of the human 60-kDa Ro autoantigen.Q42626379
Features of systemic lupus erythematosus in Dnase1-deficient miceQ42801296
Binding of antibodies to the extractable nuclear antigens SS-A/Ro and SS-B/La is induced on the surface of human keratinocytes by ultraviolet light (UVL): implications for the pathogenesis of photosensitive cutaneous lupusQ43506001
The Ro ribonucleoprotein particle: induction of autoantibodies and the detection of Ro RNAs among speciesQ44666640
Human Ro60 (SSA2) genomic organization and sequence alterations, examined in cutaneous lupus erythematosusQ48313140
Differential expression of multiple U1 small nuclear RNAs in oocytes and embryos of Xenopus laevisQ48387090
Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genomeQ48399777
Characterization of two xenopus somatic 5S DNAs and one minor oocyte-specific 5S DNAQ48413653
Differential control of U1 small nuclear RNA expression during mouse developmentQ48452707
A possible role for the 60-kD Ro autoantigen in a discard pathway for defective 5S rRNA precursors.Q49077471
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodiesQ57089602
A Susceptibility Locus for Human Systemic Lupus Erythematosus (hSLE1) on Chromosome 2qQ57462046
Antibody to nuclear ribonucleoprotein penetrates live human mononuclear cells through Fc receptorsQ59060502
Mechanisms of cellular penetration and nuclear localization of an anti-double strand DNA autoantibodyQ64389359
Ro ribonucleoprotein assembly in vitro. Identification of RNA-protein and protein-protein interactionsQ67543682
Sera from patients with autoimmune disease recognize conformational determinants on the 60-kd ro/ss-a proteinQ67692114
Autoantibodies to the Ro/SSA antigen are conformation dependent. I: Anti-60 kD antibodies are mainly directed to the native protein; anti-52 kD antibodies are mainly directed to the denatured proteinQ67808536
Identification and purification of a 55K polypeptide in Sjögren's syndrome A antigenQ70491311
Y3 is the most conserved small RNA component of Ro ribonucleoprotein complexes in vertebrate speciesQ71680743
Purification of antigenically intact Ro ribonucleoproteins; biochemical and immunological evidence that the 52-kD protein is not a Ro proteinQ72295350
The autoantibody response to Ro/SSA in cutaneous lupus erythematosusQ72765265
Autoantibodies to ribosomal P proteins penetrate into live hepatocytes and cause cellular dysfunction in cultureQ73588689
Neonatal lupus syndromesQ73911017
Counterimmunoelectrophoresis, ELISA and immunoblotting detection of anti-Ro/SSA antibodies in subacute cutaneous lupus erythematosus. A comparative studyQ74425321
Development of Autoantibodies before the Clinical Onset of Systemic Lupus ErythematosusQ79171865
P433issue4
P304page(s)232-239
P577publication date2004-04-01
P1433published inJournal of Molecular MedicineQ6295593
P1476titleThe Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity
P478volume82

Reverse relations

cites work (P2860)
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Q24681133An ortholog of the Ro autoantigen functions in 23S rRNA maturation in D. radiodurans
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Q24670318Functional requirement of noncoding Y RNAs for human chromosomal DNA replication
Q26866273Functional roles of non-coding Y RNAs
Q40040970Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control.
Q36716813Issues and advances in the management and pathogenesis of cutaneous lupus erythematosus
Q38179183Molecular mechanisms of congenital heart block
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Q36703642Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain
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Q28603163Structural and functional analysis of four non-coding Y RNAs from Chinese hamster cells: identification, molecular dynamics simulations and DNA replication initiation assays
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Q37112613The subcellular distribution of an RNA quality control protein, the Ro autoantigen, is regulated by noncoding Y RNA binding
Q92434758YRNAs overexpression and potential implications in allergy

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