Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia.

scientific article published on 22 September 2015

Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.STEM.2015.08.011
P932PMC publication ID4636971
P698PubMed publication ID26412561

P50authorAndrei KrivtsovQ55167983
Christian BachQ58032682
P2093author name stringHong Zhang
Daniel G Tenen
Henry Yang
Robert S Welner
Philipp B Staber
Scott A Armstrong
Junyan Zhang
Min Ye
Elena Levantini
Richard Koche
Monica Cusan
P2860cites workMOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP functionQ24557551
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalizationQ24603527
Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alphaQ28589867
IDH mutation impairs histone demethylation and results in a block to cell differentiationQ29305058
Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaQ33686199
T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.Q33687647
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.Q33711497
C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesisQ33919670
The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cellsQ34318485
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome positionQ34375601
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemiaQ34403931
PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2Q34577769
Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?Q34661217
Impaired Energy Homeostasis in C/EBPα Knockout MiceQ34662358
Immunogenetics. Chromatin state dynamics during blood formationQ35546671
C/EBPalpha mutations in acute myeloid leukaemiasQ35762456
BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid LeukemiaQ35762941
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.Q35898171
Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo cultureQ36380522
Notch pathway activation targets AML-initiating cell homeostasis and differentiationQ36603527
C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescenceQ37192706
STAT5 is crucial to maintain leukemic stem cells in acute myelogenous leukemias induced by MOZ-TIF2.Q37565082
Initiation of MLL-rearranged AML is dependent on C/EBPαQ38310200
Clonal development of the acute leukemias.Q38624784
Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.Q39781275
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.Q40219637
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.Q40252270
C/EBP alpha: a critical regulator of genes governing integrative metabolic processesQ41005354
Transcription factors, normal myeloid development, and leukemiaQ41534189
Common and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemiasQ42010591
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.Q53362332
C/EBPbeta is required for 'emergency' granulopoiesis.Q53619729
Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating CellsQ57615422
Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cellsQ59599864
Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid LeukemiaQ64008436
Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemiaQ71099953
Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor familyQ77483328
Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cellsQ81394615
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)611-623
P577publication date2015-09-24
P1433published inCell Stem CellQ2943975
P1476titleHematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia
P478volume17

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