ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis

scientific article published on 30 May 2015

ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1050733148
P356DOI10.1186/S13046-015-0174-1
P932PMC publication ID4486428
P698PubMed publication ID26024660
P5875ResearchGate publication ID277406669

P2093author name stringPi-feng Jia
Shi-ming Zhang
Zhi-qing Zhang
Li-sen Qin
P2860cites workSalinomycin as a drug for targeting human cancer stem cellsQ21285139
p53 opens the mitochondrial permeability transition pore to trigger necrosisQ24338796
Salinomycin: a novel anti-cancer agent with known anti-coccidial activitiesQ26853644
Cancer statistics, 2014Q27861018
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell deathQ28242641
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell deathQ28242653
Identification of selective inhibitors of cancer stem cells by high-throughput screeningQ28255115
Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: differences between primary and cancer cellsQ28290002
Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen speciesQ28483896
Salinomycin activates AMP-activated protein kinase-dependent autophagy in cultured osteoblastoma cells: a negative regulator against cell apoptosisQ28537665
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemiaQ28585666
The short chain cell-permeable ceramide (C6) restores cell apoptosis and perifosine sensitivity in cultured glioblastoma cells.Q55461469
Neuro-oncology: Therapeutic benefits of reirradiation for recurrent brain tumors.Q55463796
Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cellsQ33547230
Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatmentQ33695152
Butein suppresses breast cancer growth by reducing a production of intracellular reactive oxygen speciesQ33781991
Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioningQ34113365
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.Q34406704
Autologous antibody to src-homology 3-domain GRB2-like 1 specifically increases in the sera of patients with low-grade gliomasQ34439167
The permeability transition pore complex: another view.Q34648839
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cellsQ35164584
Platelet derived growth factor and fibroblast growth factor basic levels in the vitreous of patients with vitreoretinal disordersQ35303617
Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stressQ35653860
Calcium, mitochondria and reperfusion injury: a pore way to die.Q36424289
Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of gliomaQ36560956
Role of the mitochondrial membrane permeability transition in cell deathQ36669154
Mitochondrial permeability transition and cell death: the role of cyclophilin dQ36756460
Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells.Q37043022
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's diseaseQ37463481
The neurobiology of gliomas: from cell biology to the development of therapeutic approachesQ37910730
Understanding high grade glioma: molecular mechanism, therapy and comprehensive managementQ38075981
Curcumin-induced melanoma cell death is associated with mitochondrial permeability transition pore (mPTP) openingQ39003918
Gemcitabine-induced pancreatic cancer cell death is associated with MST1/cyclophilin D mitochondrial complexationQ39004159
P53 dependent mitochondrial permeability transition pore opening is required for dexamethasone-induced death of osteoblastsQ39016683
The mitochondrial cyclophilin D/p53 complexation mediates doxorubicin-induced non-apoptotic death of A549 lung cancer cellsQ39042820
Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen speciesQ39115194
Cisplatin-induced non-apoptotic death of pancreatic cancer cells requires mitochondrial cyclophilin-D-p53 signalingQ39127214
Oxygen glucose deprivation (OGD)/re-oxygenation-induced in vitro neuronal cell death involves mitochondrial cyclophilin-D/P53 signaling axisQ39209857
Ultra-violet B (UVB)-induced skin cell death occurs through a cyclophilin D intrinsic signaling pathwayQ39297611
Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarizationQ39483733
The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor.Q39707343
Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.Q44049211
Neuro-oncology: late neurocognitive decline after radiotherapy for low-grade gliomaQ48392946
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)57
P577publication date2015-05-30
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis
P478volume34

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cites work (P2860)
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Q37158877Combination of salinomycin and silver nanoparticles enhances apoptosis and autophagy in human ovarian cancer cells: an effective anticancer therapy
Q36534051Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition
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Q57147999Ionophores: Potential Use as Anticancer Drugs and Chemosensitizers
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Q42371490Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells.
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Q51737455SC79 protects dopaminergic neurons from oxidative stress.
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