Genetically associated CD16(+)56(-) natural killer cell interferon (IFN)-αR expression regulates signaling and is implicated in IFN-α-induced hepatitis C virus decline

scientific article published on 20 February 2012

Genetically associated CD16(+)56(-) natural killer cell interferon (IFN)-αR expression regulates signaling and is implicated in IFN-α-induced hepatitis C virus decline is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/INFDIS/JIS027
P932PMC publication ID3295604
P698PubMed publication ID22351942
P5875ResearchGate publication ID221849000

P50authorRonald BlantonQ42855342
Benigno RodriguezQ42870636
P2093author name stringClifford V Harding
Donald D Anthony
Nicole L Yonkers
Gareth Hardy
Yngve Falck-Ytter
Sara J Conry
Julia M Sugalski
Perica Davitkov
Qinglai Meng
Amy Hirsch
Anita Compan
P2860cites workIn vivo significance of NK cell on resistance against virus (HSV-1) infections in miceQ45804239
Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment.Q47747530
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Expansion of CD56- NK cells in chronic HCV/HIV-1 co-infection: reversion by antiviral treatment with pegylated IFNalpha and ribavirin.Q50568553
Severe herpesvirus infections in an adolescent without natural killer cellsQ55984308
APRI: an easy and validated predictor of hepatic fibrosis in chronic hepatitis CQ79852758
Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killingQ82639999
Differential Effects of Hepatitis C Virus JFH1 on Human Myeloid and Plasmacytoid Dendritic CellsQ27488392
Effect of Killer Immunoglobulin-Like Receptors in the Response to Combined Treatment in Patients with Chronic Hepatitis C Virus InfectionQ27490541
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infectionQ27860901
Hepatitis C virus infectionQ27861002
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearanceQ28255243
Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokinesQ28260203
Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patientsQ28274666
Peginterferon Alfa-2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected personsQ28274676
Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virusQ28279955
Pegylated interferon alfa-2b vs standard interferon alfa-2b, plus ribavirin, for chronic hepatitis C in HIV-infected patients: a randomized controlled trialQ28298301
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapyQ29614896
Estimating African American admixture proportions by use of population-specific allelesQ29616216
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis CQ29619541
Pharmacodynamics of PEG-IFN-alpha-2a in HIV/HCV co-infected patients: implications for treatment outcomesQ34208650
Estimating progression to cirrhosis in chronic hepatitis C virus infection.Q34389608
The developmental relationship between NK cells and T cellsQ35451601
Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C.Q35964254
IL28B and the Control of Hepatitis C Virus InfectionQ37800518
Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection.Q39723501
Histone deacetylase inhibitors suppress natural killer cell cytolytic activityQ40161252
NK sensitivity of neuroblastoma cells determined by a highly sensitive coupled luminescent methodQ40349680
Ontogeny, specific functions and receptors of human natural killer cellsQ40705353
Brief report: killer cell defect and persistent immunological abnormalities in two patients with chronic active Epstein-Barr virus infectionQ40774717
Immunological alterations associated with recurrent herpes simplex genitalisQ41888487
Impaired plasmacytoid dendritic cell (PDC)-NK cell activity in viremic human immunodeficiency virus infection attributable to impairments in both PDC and NK cell functionQ42614451
Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infectionQ42938534
HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infectionQ42986755
Pharmacogenomics. Gene variants affect hepatitis C treatment, but link is elusiveQ43001077
Activating NK cell receptor expression/function (NKp30, NKp46, DNAM-1) during chronic viraemic HCV infection is associated with the outcome of combined treatmentQ43037932
Expansion of functionally skewed CD56-negative NK cells in chronic hepatitis C virus infection: correlation with outcome of pegylated IFN-alpha and ribavirin treatmentQ44873615
Altered interferon-alpha-signaling in natural killer cells from patients with chronic hepatitis C virus infectionQ45375236
Immunological studies of herpes simplex virus infection in children with atopic eczemaQ45769131
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectHepatitis C virusQ708693
P304page(s)1131-1141
P577publication date2012-02-20
P1433published inJournal of Infectious DiseasesQ4051141
P1476titleGenetically associated CD16(+)56(-) natural killer cell interferon (IFN)-αR expression regulates signaling and is implicated in IFN-α-induced hepatitis C virus decline
P478volume205

Reverse relations

cites work (P2860)
Q36408274Baseline levels of soluble CD14 and CD16+56- natural killer cells are negatively associated with response to interferon/ribavirin therapy during HCV-HIV-1 coinfection
Q36901142Effect of CD16a, the surface receptor of Kupffer cells, on the growth of hepatocellular carcinoma cells
Q40238137HCV viraemia associates with NK cell activation and dysfunction in antiretroviral therapy-treated HIV/HCV-co-infected subjects.
Q33694920Hepatitis C Virus and Human Cytomegalovirus-Natural Killer Cell Subsets in Persistent Viral Infections
Q37719750Natural cytotoxicity receptor-dependent natural killer cytolytic activity directed at hepatitis C Virus (HCV) is associated with liver inflammation, African American race, IL28B genotype, and response to pegylated interferon/ribavirin therapy in chr
Q26773264Natural killer cells in hepatitis C: Current progress
Q37279158The natural killer cell response to HCV infection.