Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

scientific article published on 23 May 2015

Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1051843441
P356DOI10.1186/S40478-015-0209-Z
P932PMC publication ID4489160
P698PubMed publication ID26001591
P5875ResearchGate publication ID277937956

P50authorRichard John KryscioQ102165574
Adam D BachstetterQ56441597
Erin L AbnerQ60665975
Frederick A. SchmittQ64778804
Peter T NelsonQ90936675
Linda J Van EldikQ99563495
P2093author name stringEla Patel
Eseosa T Ighodaro
Janna H Neltner
Scott J Webster
P2860cites workTREM2 Variants in Alzheimer's DiseaseQ22250873
Variant of TREM2 Associated with the Risk of Alzheimer's DiseaseQ22250874
Microglial pathologyQ26992285
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain diseaseQ26996741
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivoQ27860578
Microglia-specific localisation of a novel calcium binding protein, Iba1Q28273977
Identification of a unique TGF-β-dependent molecular and functional signature in microgliaQ28303557
Physiology of microgliaQ29547414
ATP mediates rapid microglial response to local brain injury in vivoQ29547872
Rod microglia: a morphological definitionQ33618424
Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly personsQ33828911
Microglial senescence: does the brain's immune system have an expiration date?Q34550017
Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based studyQ34738383
Hippocampal sclerosis in advanced age: clinical and pathological features.Q34992164
University of Kentucky Sanders-Brown healthy brain aging volunteers: donor characteristics, procedures and neuropathologyQ36131008
Morphological and genetic activation of microglia after diffuse traumatic brain injury in the rat.Q36372703
Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury.Q36478500
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literatureQ36575903
Neuroinflammatory phenotype in early Alzheimer's diseaseQ36629135
The p38α MAPK regulates microglial responsiveness to diffuse traumatic brain injury.Q36887359
Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid betaQ36996975
CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.Q37093860
Increased activation of Iba1+ microglia in pediatric epilepsy patients with Rasmussen's encephalitis compared with cortical dysplasia and tuberous sclerosis complexQ37195038
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's diseaseQ37331433
The microglial sensome revealed by direct RNA sequencingQ37341692
Morphometric characterization of microglial phenotypes in human cerebral cortexQ37532369
Microglial dysfunction in brain aging and Alzheimer's diseaseQ37678533
Changing face of microgliaQ37807203
Microglial activation in the injured and healthy brain: what are we really talking about? Practical and theoretical issues associated with the measurement of changes in microglial morphologyQ38028703
Review: activation patterns of microglia and their identification in the human brain.Q38068503
The human side of microgliaQ38175607
New stereological methods for counting neuronsQ40843719
Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages.Q40904050
Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathologyQ42276637
Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal proteinQ42993102
Dystrophic microglia in the aging human brainQ48090856
Fusion of microglia with pyramidal neurons after retroviral infection.Q48380856
Microglial pathology in Down syndromeQ48946346
Hippocampal sclerosis: a common pathological feature of dementia in very old (> or = 80 years of age) humans.Q52059797
Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.Q53392859
The unbiased estimation of number and sizes of arbitrary particles using the disectorQ71397942
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
dementiaQ83030
microgliaQ1622829
hippocampal sclerosisQ4421929
dementia with Lewy bodiesQ101245788
P304page(s)32
P577publication date2015-05-23
P1433published inActa Neuropathologica CommunicationsQ27724912
P1476titleDisease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging
P478volume3

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