Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages

scientific article published on April 1988

Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI113427
P932PMC publication ID329641
P698PubMed publication ID3280600

P2093author name stringJ R Perfect
D L Granger
J B Hibbs
D T Durack
P2860cites workL-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cellsQ68981146
Recombinant mouse gamma interferon induces the priming step in macrophage activation for tumor cell killingQ70428568
Nitrate synthesis in the germfree and conventional ratQ70542428
Effects of activated macrophages on tumor target cells in discrete phases of the cell cycleQ71393808
Defensins. Natural peptide antibiotics of human neutrophilsQ24563852
An endotoxin-induced serum factor that causes necrosis of tumorsQ24564406
Fungicidal activity of rabbit alveolar and peritoneal macrophages against Candida albicansQ33904365
Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversibleQ34539273
Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxideQ34547882
Chronic cryptococcal meningitis: a new experimental model in rabbitsQ35863351
Sites of inhibition of mitochondrial electron transport in macrophage-injured neoplastic cellsQ36209398
Increased superoxide anion production by immunologically activated and chemically elicited macrophagesQ36341599
Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediatesQ36342907
Subcellular location and properties of bactericidal factors from human neutrophilsQ36353129
Nitrate biosynthesis in manQ36384530
Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respirationQ37020243
Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatmentQ37343268
Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharideQ37555750
Magnitude of the host nutritional responses to infectionQ39864510
A Reevaluation of the Roles of the O2-Dependent and O2-Independent Microbicidal Systems of PhagocytesQ40161623
Pigment production by Cryptococcus neoformans from para- and ortho-Diphenols: effect of the nitrogen sourceQ40238982
Leukocyte endogenous mediator alters protein dynamics in ratsQ40834891
Oxidation of ammonia and hydroxylamine to nitrate in the rat and in vitroQ41592652
Associations of ninhydrin-reacting compounds in the seeds of 49 species of LathyrusQ41960747
Activated macrophages secrete a soluble factor that inhibits mitochondrial respiration of tumor cellsQ43885432
Iron depletion: possible cause of tumor cell cytotoxicity induced by activated macrophagesQ46261881
Cytostatic effects of activated macrophages on tumor target cells: inhibition of cytotoxic action of ARA-C.Q46692628
Macrophage-mediated fungistasis: requirement for a macromolecular component in serum.Q50908532
Activated oxygen and mammalian nitrate biosynthesis.Q53551041
Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages.Q54012804
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.Q55057549
Activated macrophages kill tumour cells by releasing arginaseQ59065414
Macrophage-mediated fungistasis in vitro: requirements for intracellular and extracellular cytotoxicityQ68857500
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)1129-1136
P577publication date1988-04-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleSpecific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages
P478volume81

Reverse relations

cites work (P2860)
Q344705268-nitroguanosine formation in viral pneumonia and its implication for pathogenesis
Q64082805A Systems Vaccinology Approach Reveals the Mechanisms of Immunogenic Responses to Hantavax Vaccination in Humans
Q42848232A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
Q36513491ALL2, a Homologue of ALL1, Has a Distinct Role in Regulating pH Homeostasis in the Pathogen Cryptococcus neoformans.
Q36356195Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide
Q35785931Acute effects of inhaled urban particles and ozone: lung morphology, macrophage activity, and plasma endothelin-1.
Q34153407Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.
Q36356019An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro
Q71730956Antifungal mechanisms of activated murine bronchoalveolar or peritoneal macrophages for Histoplasma capsulatum
Q42463616Antimicrobial and respiratory burst characteristics of pulmonary alveolar macrophages recovered from smokers of marijuana alone, smokers of tobacco alone, smokers of marijuana and tobacco, and nonsmokers
Q73026484Assessment of bovine mononuclear phagocytes and neutrophils for induced L-arginine-dependent nitric oxide production
Q39714048Assessment of safety of lactobacillus strains based on resistance to host innate defense mechanisms
Q38003366Beneficial actions of melatonin in the management of viral infections: a new use for this "molecular handyman"?
Q37126054Beta-glucans, history, and the present: immunomodulatory aspects and mechanisms of action
Q43145768Biocompatibility of acellular dermal matrix graft evaluated in culture of murine macrophages
Q38956742CR3-dependent phagocytosis by murine macrophages: different cytokines regulate ingestion of a defined CR3 ligand and complement-opsonized Cryptococcus neoformans
Q50045987Caloric restriction increases free radicals and inducible nitric oxide synthase expression in mice infected with Salmonella Typhimurium
Q37345802Candida albicans-macrophage interactions: genomic and proteomic insights
Q35780552Cryptococcus neoformans Infection in Mice Lacking Type I Interferon Signaling Leads to Increased Fungal Clearance and IL-4-Dependent Mucin Production in the Lungs.
Q39821669Cryptococcus neoformans fails to induce nitric oxide synthase in primed murine macrophage-like cells
Q33946649Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection
Q38229538Current concepts in cryptococcosis
Q40840535Cytokines and nitric oxide as effector molecules against parasitic infections
Q77164099Cytokines as therapy for opportunistic fungal infections
Q35042527Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase
Q77907848Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues
Q39827212Development of an in vitro macrophage system to assess Penicillium marneffei growth and susceptibility to nitric oxide
Q33922362Dietary vitamin E and T cell-mediated function in the elderly: effectiveness and mechanism of action.
Q43636335Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide
Q54567819Differential response of splenic monocytes and DC from cattle to microbial stimulation with Mycobacterium bovis BCG and Babesia bovis merozoites.
Q36999560Differential stimulation of murine resident peritoneal cells by selectively opsonized encapsulated and acapsular Cryptococcus neoformans
Q37691488EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages
Q44704028Effect of L-arginine analogs and a calcium chelator on nitric oxide (NO) production by Leishmania sp.
Q34931672Effect of cytokine interplay on macrophage polarization during chronic pulmonary infection with Cryptococcus neoformans
Q71781482Effect of nitric oxide donors on survival of conidia, germination and growth of Aspergillus fumigatus in vitro
Q36951075Effect of pyocyanine, a pigment of Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by murine alveolar macrophages
Q35124444Effect of recombinant human gamma interferon on intracellular activities of antibiotics against Listeria monocytogenes in the human macrophage cell line THP-1.
Q63247612Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophages
Q36972580Endogenous tumor necrosis factor alpha is required for enhanced antimicrobial activity against Toxoplasma gondii and Listeria monocytogenes in recombinant gamma interferon-treated mice
Q39784797Enhancement of nitric oxide synthesis by macrophages represents an additional mechanism of action for amphotericin B.
Q44653973Enzymes that Counteract Nitrosative Stress Promote Fungal Virulence
Q41021483Evidence for antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication
Q41020550Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts. A new microbicidal pathway for polymorphonuclear leukocytes
Q36850165Genetic regulation of macrophage priming/activation: the Lsh gene story
Q34532078Group B streptococcus-induced nitric oxide production in murine macrophages is CR3 (CD11b/CD18) dependent.
Q36980669Growth inhibition of Cryptococcus neoformans by cultured human monocytes: role of the capsule, opsonins, the culture surface, and cytokines
Q36363319Human astrocytes inhibit Cryptococcus neoformans growth by a nitric oxide-mediated mechanism
Q33649553Human defenses against Cryptococcus neoformans: an update
Q33672060Identification of arginine as a precursor of endothelium-derived relaxing factor
Q37957849Immunological aspects of fungal pathogenesis
Q64054632Immunometabolism of Phagocytes and Relationships to Cardiac Repair
Q44662507Immunostimulatory DNA from Paracoccidioides brasiliensis acts as T-helper 1 promoter in susceptible mice.
Q34230852In vitro evaluation of a new treatment for urinary tract infections caused by nitrate-reducing bacteria
Q35433678In vivo regulation of replicative Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide
Q35027324Induction of nitric oxide synthase in vivo and cell injury in rat duodenal epithelium by a water soluble extract of Helicobacter pylori
Q41624291Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages
Q39830479Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice
Q43896587Infection and nitric oxide
Q35422948Ingestion of acapsular Cryptococcus neoformans occurs via mannose and beta-glucan receptors, resulting in cytokine production and increased phagocytosis of the encapsulated form
Q34117500Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis
Q34532614Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: role of reactive oxygen species, nitric oxide, tryptophan, and iron(III).
Q39590479Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus.
Q77995140Interferon-gamma (IFN-gamma)-dependent protection and synthesis of chemoattractants for mononuclear leucocytes caused by IL-12 in the lungs of mice infected with Cryptococcus neoformans
Q34237322Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells
Q44907215Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans
Q36958434Intracellular growth inhibition of Histoplasma capsulatum induced in murine macrophages by recombinant gamma interferon is not due to a limitation of the supply of methionine or cysteine to the fungus
Q35410685Intracellular killing of Listeria monocytogenes in the J774.1 macrophage-like cell line and the lipopolysaccharide (LPS)-resistant mutant LPS1916 cell line defective in the generation of reactive oxygen intermediates after LPS treatment
Q34118196Investigation of role of nitric oxide in protection from Bordetella pertussis respiratory challenge
Q35512116Involvement of reactive oxygen intermediates in tumor necrosis factor alpha-dependent bacteriostasis of Mycobacterium avium.
Q41447238Iron regulates nitric oxide synthase activity by controlling nuclear transcription
Q36968605Killing of Plasmodium falciparum in vitro by nitric oxide derivatives
Q42475424L-arginine-dependent destruction of intrahepatic malaria parasites in response to tumor necrosis factor and/or interleukin 6 stimulation
Q41725075L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen
Q34002542Laccase protects Cryptococcus neoformans from antifungal activity of alveolar macrophages
Q39822116Lack of involvement of nitric oxide in killing of Aspergillus fumigatus conidia by pulmonary alveolar macrophages
Q36362384Listeria meningitis: identification of a cerebrospinal fluid inhibitor of macrophage listericidal function as interleukin 10
Q54056915Local activation of nonspecific defense against a respiratory model infection by application of interferon-gamma: comparison between rat alveolar and interstitial lung macrophages.
Q36935291Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection
Q42091310Macrophage activation for intracellular killing as induced by a Ca2+ ionophore. Dependence on l-arginine-derived nitrogen oxidation products
Q40885442Macrophage interactions in toxoplasmosis
Q36968357Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: role of reactive nitrogen intermediates
Q34240927Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages
Q36192349Microbial strategies to prevent oxygen-dependent killing by phagocytes
Q35115708Monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan enhance fluconazole efficacy
Q33754371Mouse-human immunoglobulin G1 chimeric antibodies with activities against Cryptococcus neoformans
Q68361554Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis
Q24633512Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice
Q33858380Nitric oxide and peroxynitrite in the perinatal period.
Q27485884Nitric oxide and virus infection
Q36684502Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity
Q34874996Nitric oxide in respiratory diseases.
Q34546031Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro
Q36362030Nitric oxide localized to spinal cords of mice with experimental allergic encephalomyelitis: an electron paramagnetic resonance study
Q42164304Nitric oxide produced in Peyer's patches exhibits antiapoptotic activity contributing to an antimicrobial effect in murine salmonellosis
Q41856492Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: a review
Q47915703Nitric oxide production in human macrophagic cells phagocytizing opsonized zymosan: direct characterization by measurement of the luminol dependent chemiluminescence.
Q41299658Nitric oxide synthesis by rat pleural mesothelial cells: induction by growth factors and lipopolysaccharide
Q74591765Nitric oxide synthesis during acute SIV mac251 infection of macaques
Q33604156Nitric oxide synthesis enhances human immunodeficiency virus replication in primary human macrophages
Q44221658Nitric oxide synthesis in the CNS, endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues
Q36436856Nitric oxide, a biological effector. Electron paramagnetic resonance detection of nitrosyl-iron-protein complexes in whole cells.
Q41052100Nitric oxide-mediated cytotoxic effects of alveolar macrophages on transformed lung epithelial cells are independent of the beta 2 integrin-mediated intercellular adhesion
Q40399921Nitric oxide. Novel biology with clinical relevance
Q43832923Nitrogen oxide levels in patients after trauma and during sepsis
Q47829527Pathophysiological chemistry of nitric oxide and its oxygenation by-products.
Q37322024Protective role of nitric oxide in ocular toxoplasmosis
Q39512732Reactive nitrogen and oxygen species ameliorate experimental cryptosporidiosis in the neonatal BALB/c mouse model.
Q35609727Regulation of inflammatory responses to Bordetella pertussis by N(G)-monomethyl-L-arginine in mice intranasally infected
Q72041326Release of reactive oxygen and nitrogen intermediates from monocytes of patients with pulmonary tuberculosis
Q33596326Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis
Q50120579Role of Pasteurella multocida, Pasteurella haemolytica and Salmonella typhimurium porins on inducible nitric oxide release by murine macrophages
Q37982832Role of arginine in trauma, sepsis, and immunity
Q34191797Role of free radicals in viral pathogenesis and mutation
Q39401256Role of inorganic nitrogen oxides and tumor necrosis factor alpha in killing Leishmania donovani amastigotes in gamma interferon-lipopolysaccharide-activated macrophages from Lshs and Lshr congenic mouse strains
Q39655032Role of nitric oxide in host defense in murine salmonellosis as a function of its antibacterial and antiapoptotic activities
Q36656920Role of nitric oxide synthesis in macrophage antimicrobial activity
Q24683780Role of oxidants in microbial pathophysiology
Q36230297Role of transferrin, transferrin receptors, and iron in macrophage listericidal activity
Q34289451STAT1 signaling is essential for protection against Cryptococcus neoformans infection in mice
Q36281328STAT1 signaling within macrophages is required for antifungal activity against Cryptococcus neoformans
Q50191058Sensitivity of bacteria to NaNO2 and to L-arginine-dependent system in murine macrophages
Q35762897Stimulation of unprimed macrophages with immune complexes triggers a low output of nitric oxide by calcium-dependent neuronal nitric-oxide synthase
Q28369007Strains of Mycobacterium tuberculosis differ in susceptibility to reactive nitrogen intermediates in vitro
Q54183886Synergy of fluconazole with macrophages for antifungal activity against Candida albicans.
Q37041650Synthesis of nitric oxide from L-arginine: a recently discovered pathway induced by cytokines with antitumour and antimicrobial activity
Q40507021The emerging multifaceted roles of nitric oxide
Q33716138The gamma interferon receptor is required for the protective pulmonary inflammatory response to Cryptococcus neoformans
Q71834571The involvement of nitric oxide in the anti-Candida albicans activity of rat neutrophils
Q35193841The metabolic effects of thermal injury
Q41600919The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta
Q40373297The regulation of pulmonary immunity.
Q54323502The role of macrophage activation and of Bcg-encoded macrophage function(s) in the control of Mycobacterium avium infection in mice.
Q33751411Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B.
Q35457307Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages
Q38193589Tumour-induced immune suppression: role of inflammatory mediators released by myelomonocytic cells.
Q36720631Two unique aspects of inducible .N=0 synthase in liver cells and accessory cells: hepatic damage is minimized by hepatocyte .N=0 production and immunoregulation is mediated by macrophage. .N=O production

Search more.