The roles of microRNAs and protein components of the microRNA pathway in lung development and diseases

scientific article published in April 2015

The roles of microRNAs and protein components of the microRNA pathway in lung development and diseases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1165/RCMB.2014-0232RT
P932PMC publication ID4491123
P698PubMed publication ID25211015

P2093author name stringJining Lü
Zhihua Jiang
Leah Cushing
Pingping Kuang
P2860cites workExportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAsQ24302072
miR-145 and miR-143 regulate smooth muscle cell fate and plasticityQ24311186
MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesisQ37340592
miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.Q37393628
Dicer1 functions as a haploinsufficient tumor suppressorQ37457958
Retinoid induction of alveolar regeneration: from mice to man?Q37463601
Lung development: orchestrating the generation and regeneration of a complex organQ37507601
Prenatal retinoid deficiency leads to airway hyperresponsiveness in adult miceQ37524260
MicroRNA regulation of smooth muscle gene expression and phenotypeQ37580458
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.Q37631219
Molecular determinants of lung developmentQ37639254
mir-17-92: a polycistronic oncomir with pleiotropic functionsQ37678802
LATS tumor suppressor: a new governor of cellular homeostasisQ37799215
MicroRNAs in inflammatory lung disease--master regulators or target practice?Q37804482
Involvement of microRNAs in physiological and pathological processes in the lungQ37811102
Patterning and plasticity in development of the respiratory lineageQ37845286
The emerging role of microRNAs in asthmaQ37850367
MicroRNAs in idiopathic pulmonary fibrosis.Q37855082
MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodellingQ37953895
Evolution of microRNA diversity and regulation in animalsQ37957677
The role and regulation of microRNAs in asthmaQ37966852
Wnt/beta-catenin signaling: a promising new target for fibrosis diseases.Q38016472
microRNAs in asthma: potential therapeutic targetsQ38055299
TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?Q38060682
Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signalingQ24321740
Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancerQ24338421
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAsQ24537328
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genesQ24537363
Identification of mammalian microRNA host genes and transcription unitsQ24562298
MicroRNA genes are transcribed by RNA polymerase IIQ24562649
Inhibition and role of let-7d in idiopathic pulmonary fibrosisQ24599153
MicroRNAs: target recognition and regulatory functionsQ24609584
Preparing for the first breath: genetic and cellular mechanisms in lung developmentQ24633128
miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distributionQ24644506
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clustersQ24645192
MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injuryQ24647407
MicroRNA regulation of cell lineages in mouse and human embryonic stem cellsQ24655106
MicroRNA-127 modulates fetal lung developmentQ24657624
Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cellsQ24685393
The Hippo pathway effectors TAZ and YAP in development, homeostasis and diseaseQ26852353
miR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart developmentQ27320478
Argonaute2 is the catalytic engine of mammalian RNAiQ27860545
The functions of animal microRNAsQ27860621
A microRNA polycistron as a potential human oncogeneQ27860720
MicroRNAs: small RNAs with a big role in gene regulationQ27860896
c-Myc-regulated microRNAs modulate E2F1 expressionQ27861046
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
MicroRNA expression profiles classify human cancersQ28032481
The diverse functions of microRNAs in animal development and diseaseQ28266193
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferationQ28280072
let-7 and miR-17-92: small-sized major players in lung cancer developmentQ28291431
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancerQ28291502
Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92Q28294917
Induction of microRNA-1 by myocardin in smooth muscle cells inhibits cell proliferationQ28297726
A microRNA component of the p53 tumour suppressor networkQ28305330
Regulation of lung endoderm progenitor cell behavior by miR302/367Q28505583
Dicer function is essential for lung epithelium morphogenesisQ28506135
The role of GW182 proteins in miRNA-mediated gene silencingQ38066080
The Hippo pathway and human cancer.Q38087215
TAZ is a novel oncogene in non-small cell lung cancer.Q38337901
The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7Q39044895
MiR-449c targets c-Myc and inhibits NSCLC cell progressionQ39178996
Targeting of the signal transducer Smo links microRNA-326 to the oncogenic Hedgehog pathway in CD34+ CML stem/progenitor cellsQ39206405
Effect of miR-34b overexpression on the radiosensitivity of non-small cell lung cancer cell lines.Q39346975
Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancerQ39448960
microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4.Q39561335
MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1.Q39598705
MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypesQ39926867
p53-mediated activation of miRNA34 candidate tumor-suppressor genes.Q40102003
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivoQ41455736
Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cellsQ41827465
Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis.Q41915170
Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.Q42051146
Intact p53-dependent responses in miR-34-deficient mice.Q42251432
MicroRNA profiling implicates the insulin-like growth factor pathway in bleomycin-induced pulmonary fibrosis in miceQ42590406
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in miceQ42722532
Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.Q43140506
Reduced expression of Dicer associated with poor prognosis in lung cancer patients.Q43573248
DICER1 syndrome: a new cancer syndromeQ43732961
Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylationQ48084508
Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice.Q50694421
Role of Sonic Hedgehog in idiopathic pulmonary fibrosis.Q50782600
Epithelial/mesenchymal interactions and branching morphogenesis of the lung.Q52565573
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer.Q53306726
Profiling of miRNAs in pediatric asthma: upregulation of miRNA-221 and miRNA-485-3p.Q54296590
Gene expression networks in COPD: microRNA and mRNA regulation.Q54347289
miR-26a linked to pulmonary hypertension by global assessment of circulating extracellular microRNAs.Q54455331
MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo.Q54566995
Erratum: Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathwayQ58034765
Low miR-145 and high miR-367 are associated with unfavourable prognosis in resected nonsmall cell lung cancerQ62022649
A Role for miR-145 in Pulmonary Arterial HypertensionQ63916426
MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epitheliaQ82508815
The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitorsQ28506288
Dicer is essential for mouse developmentQ28511142
Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endodermQ28512412
SMAD proteins control DROSHA-mediated microRNA maturationQ28941771
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesisQ29547607
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewalQ29615487
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathwaysQ29618467
miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development.Q30573413
miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110.Q30585689
MicroRNA expression profiling in mild asthmatic human airways and effect of corticosteroid therapyQ33466773
MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosisQ33799699
MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targetsQ33815996
Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular functionQ33883484
MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and functionQ33893114
Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic targetQ33909356
MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblastsQ33982509
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by DroshaQ34065396
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotalineQ34095444
miR-326 is downstream of Sonic hedgehog signaling and regulates the expression of Gli2 and smoothenedQ34103695
DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndromeQ34160764
Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulationQ34160776
Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathwayQ34186612
MicroRNA-449 in cell fate determinationQ34209660
MicroRNAs and the regulation of fibrosisQ34238322
MicroRNA in lung cancerQ34256044
MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway.Q34273664
miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-MycQ34393268
Mir-206 regulates pulmonary artery smooth muscle cell proliferation and differentiationQ34447498
Regulation of early lung morphogenesis: questions, facts and controversiesQ34513653
miRNA biogenesis enzyme Drosha is required for vascular smooth muscle cell survivalQ34700041
MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-MetQ34755653
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cellsQ34816792
DICER1 mutations in familial pleuropulmonary blastomaQ34992567
E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosisQ35015916
MiRNA in innate immune responses: novel players in wound inflammationQ35033664
Branching morphogenesis of the lung: new molecular insights into an old problemQ35057316
Wnt signaling and pulmonary fibrosisQ35111651
down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4Q35150101
miR-29 is a major regulator of genes associated with pulmonary fibrosis.Q35219800
A Shh/miR-206/BDNF cascade coordinates innervation and formation of airway smooth muscle.Q35567367
Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2.Q35598832
The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathyQ35634955
Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary diseaseQ35694443
Quantitative functions of Argonaute proteins in mammalian development.Q35882150
Lung organogenesisQ35922155
Molecular signature of a right heart failure program in chronic severe pulmonary hypertension.Q35991288
DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in miceQ36003649
MicroRNA function in animal developmentQ36235770
MicroRNA functions in animal development and human diseaseQ36285673
miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma.Q36368456
Airway epithelial miRNA expression is altered in asthma.Q36488742
Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortalityQ36678561
Transcriptional control of lung morphogenesisQ36712753
miR-145 regulates myofibroblast differentiation and lung fibrosisQ36860296
Pathobiology of pulmonary hypertensionQ37014730
Hedgehog signaling in neonatal and adult lung.Q37056427
Role of microRNAs in lung development and pulmonary diseasesQ37133793
Functionally diverse microRNA effector complexes are regulated by extracellular signalingQ37230924
Dicer, Drosha, and outcomes in patients with ovarian cancerQ37262584
Changes in microRNA and mRNA expression with differentiation of human bronchial epithelial cellsQ37297971
Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene clusterQ37328540
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)397-408
P577publication date2015-04-01
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleThe roles of microRNAs and protein components of the microRNA pathway in lung development and diseases
P478volume52

Reverse relations

cites work (P2860)
Q38641813A Circulating Micro-RNA Signature Serves as a Diagnostic and Prognostic Indicator in Sarcoidosis
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