Involvement of Toll-like receptor 2 and epidermal growth factor receptor signaling in epithelial expression of airway remodeling factors

scientific article published in April 2015

Involvement of Toll-like receptor 2 and epidermal growth factor receptor signaling in epithelial expression of airway remodeling factors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1165/RCMB.2014-0240OC
P932PMC publication ID4491124
P698PubMed publication ID25180535

P50authorAtsushi KatoQ42844846
P2093author name stringMasafumi Sakashita
Robert P Schleimer
James E Norton
Lydia A Suh
Roderick G Carter
Tetsuya Homma
P2860cites workDisordered microbial communities in asthmatic airwaysQ21562589
Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cellsQ24319679
Epidermal growth factor receptor signaling to Erk1/2 and STATs control the intensity of the epithelial inflammatory responses to rhinovirus infection.Q42524734
Regulation and function of the IL-1 family cytokine IL-1F9 in human bronchial epithelial cellsQ42844810
Altered expression of genes associated with innate immunity and inflammation in recalcitrant rhinosinusitis with polypsQ42932353
Oral steroids and doxycycline: two different approaches to treat nasal polyps.Q43069816
A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitorQ43821994
Childhood asthma after bacterial colonization of the airway in neonatesQ44570200
Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthmaQ44772766
Pathogenic bacteria colonizing the airways in asymptomatic neonates stimulates topical inflammatory mediator releaseQ46326414
The effect of marimastat, a metalloprotease inhibitor, on allergen-induced asthmatic hyper-reactivityQ46490033
Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases mRNA transcripts in the bronchial secretions of asthmatics.Q51033052
Subepithelial basement membrane immunoreactivity for matrix metalloproteinase 9: association with asthma severity, neutrophilic inflammation, and wound repair.Q51669928
Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.Q52956682
Biofilm formation and Toll-like receptor 2, Toll-like receptor 4, and NF-kappaB expression in sinus tissues of patients with chronic rhinosinusitis.Q54333336
Fibroblast growth factor-2 is a sputum remodeling biomarker of severe asthma.Q54665881
Repression of Cyclooxygenase-2 and Prostaglandin E2Release by Dexamethasone Occurs by Transcriptional and Post-transcriptional Mechanisms Involving Loss of Polyadenylated mRNAQ58450602
MMP-2- and MMP-9-linked gelatinolytic activity in the sputum from patients with asthma and chronic obstructive pulmonary diseaseQ73288136
Detecting polymorphisms in MMP genesQ73537152
Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysemaQ73629978
Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthmaQ73942360
Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthmaQ77320446
Tissue inhibitor of metalloproteinase-1 levels in bronchoalveolar lavage fluid from asthmatic subjectsQ77950307
Expression of epidermal growth factors and their receptors in the bronchial epithelium of subjects with chronic obstructive pulmonary diseaseQ82174980
Staphylococcus aureus membrane and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes through the Toll-like receptor 2-Toll-like receptor 6 pathwayQ82311958
Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory responseQ24812201
Toll-like receptorsQ27860671
Staphylococcus aureus colonization and IgE antibody formation to enterotoxins is increased in nasal polyposisQ28171130
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptorsQ28512624
The global burden of asthma: executive summary of the GINA Dissemination Committee reportQ29614904
Toll-like receptors 2, 3 and 4 and thymic stromal lymphopoietin expression in fatal asthmaQ30525313
Histamine stimulation of MMP-1(collagenase-1) secretion and gene expression in gastric epithelial cells: role of EGFR transactivation and the MAP kinase pathwayQ33291912
Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiencyQ33622543
Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathwaysQ33715487
Airway mucus function and dysfunctionQ33723578
Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthmaQ33782854
Tiotropium bromide inhibits TGF-ß-induced MMP production from lung fibroblasts by interfering with Smad and MAPK pathways in vitroQ34128938
Activation of airway epithelial cells by toll-like receptor agonistsQ34326362
Pathophysiologic mechanisms in atopic dermatitisQ34480687
TNF-α-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cellsQ35219817
Immunohistochemical localisation of the matrix metalloproteinases MMP-3 and MMP-9 within the airways in asthmaQ35533193
Bacteria in sputum of stable severe asthma and increased airway wall thicknessQ35955401
Chlamydophila pneumoniae and Mycoplasma pneumoniae: a role in asthma pathogenesis?Q36165742
Glucocorticoids enhance or spare innate immunity: effects in airway epithelium are mediated by CCAAT/enhancer binding proteinsQ36238026
Activation of epidermal toll-like receptor 2 enhances tight junction function: implications for atopic dermatitis and skin barrier repairQ36692559
Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokersQ36770692
Beyond inflammation: airway epithelial cells are at the interface of innate and adaptive immunityQ36967525
Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases.Q37283112
A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in miceQ37359009
Effect of posttranslational processing on the in vitro and in vivo activity of chemokines.Q37819144
Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathwaysQ37872216
Chronic Chlamydia pneumoniae infection and asthma exacerbations in childrenQ37881200
A therapeutic role for matrix metalloproteinase inhibitors in lung diseases?Q37887317
Basic research on virus-induced asthma exacerbation: inhibition of inflammatory chemokine expression by fluticasone propionateQ39144680
Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cellsQ39522036
Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epitheliumQ39997126
Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuliQ40303456
TLR2 signaling is critical for Mycoplasma pneumoniae-induced airway mucin expressionQ40432568
Involvement of the epidermal growth factor receptor in epithelial repair in asthmaQ40870399
Th2 cell membrane factors in association with IL-4 enhance matrix metalloproteinase-1 (MMP-1) while decreasing MMP-9 production by granulocyte-macrophage colony-stimulating factor-differentiated human monocytes.Q40878546
Marked induction of matrix metalloproteinase-10 by respiratory syncytial virus infection in human nasal epithelial cellsQ42271827
Defective epithelial barrier function in asthma.Q42491458
Relationship of epidermal growth factor receptors to goblet cell production in human bronchiQ42499386
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)471-481
P577publication date2015-04-01
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleInvolvement of Toll-like receptor 2 and epidermal growth factor receptor signaling in epithelial expression of airway remodeling factors
P478volume52

Reverse relations

cites work (P2860)
Q39431981Ezrin Orchestrates Signal Transduction in Airway Cells.
Q89975552Inhibition of Virus-Induced Cytokine Production from Airway Epithelial Cells by the Late Addition of Budesonide
Q38738551International Consensus Statement on Allergy and Rhinology: Rhinosinusitis
Q48016630Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease
Q47923013Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis
Q38721521Reduced Innate Immune Response to a Staphylococcus aureus Small Colony Variant Compared to Its Wild-Type Parent Strain
Q92716182Similar Transition Processes in Synovial Fibroblasts from Rheumatoid Arthritis and Osteoarthritis: A Single-Cell Study

Search more.