Dna2 nuclease-helicase structure, mechanism and regulation by Rpa.

scientific article published on 22 October 2015

Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.09832
P932PMC publication ID4716839
P698PubMed publication ID26491943

P2093author name stringChun Zhou
Nikola P Pavletich
Sergei Pourmal
P2860cites workBLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repairQ24293244
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Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNAQ24311910
Biochemical analysis of human Dna2Q24314609
Functional domains of the 70-kilodalton subunit of human replication protein AQ24316316
Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1Q24319140
SF1 and SF2 helicases: family mattersQ24596016
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Mechanistic basis of 5'-3' translocation in SF1B helicasesQ27655717
Crystal structures of   exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivityQ27670686
Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment ProcessingQ59444619
The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1Q27672895
Structure and conformational change of a replication protein A heterotrimer bound to ssDNAQ27674555
Structural basis for translocation by AddAB helicase-nuclease and its arrest at χ sitesQ27682528
Overview of the CCP4 suite and current developmentsQ27860782
Phasercrystallographic softwareQ27860930
Features and development of CootQ27861079
Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0Q27861104
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processingQ27929897
DNA2 Encodes a DNA Helicase Essential for Replication of Eukaryotic ChromosomesQ27933435
Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturationQ27939444
Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaksQ28292707
A dynamic model for replication protein A (RPA) function in DNA processing pathwaysQ29614213
Double-strand break end resection and repair pathway choiceQ29614422
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break endsQ29615269
Making and breaking nucleic acids: two-Mg2+-ion catalysis and substrate specificityQ29615987
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein AQ30446685
SURVEY AND SUMMARY: holliday junction resolvases and related nucleases: identification of new families, phyletic distribution and evolutionary trajectoriesQ30612214
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotesQ30704734
Bimodal interaction between replication-protein A and Dna2 is critical for Dna2 function both in vivo and in vitroQ30727947
Dynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiaeQ30847932
Recruitment of replication protein A by the papillomavirus E1 protein and modulation by single-stranded DNAQ31038703
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme.Q31423540
Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responsesQ33235763
Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complexQ33263880
Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisomeQ33292122
Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathwayQ33482605
Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.Q33681974
DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2Q33681983
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.Q34158344
Type II restriction endonucleases: structure and mechanismQ34555997
RPA coordinates DNA end resection and prevents formation of DNA hairpinsQ34740136
Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesisQ36990200
The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nucleases, is essential in vivoQ41728146
DNA helicases Sgs1 and BLM promote DNA double-strand break resectionQ42750184
An iron-sulfur cluster is essential for the binding of broken DNA by AddAB-type helicase-nucleasesQ43159932
The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing.Q53163831
P407language of work or nameEnglishQ1860
P577publication date2015-10-22
P1433published ineLifeQ2000008
P1476titleDna2 nuclease-helicase structure, mechanism and regulation by Rpa.
P478volume4

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cites work (P2860)
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