CLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p

scientific article published on 28 October 2015

CLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p is …
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scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1041429F
P356DOI10.1371/JOURNAL.PONE.0141429
P932PMC publication ID4625016
P698PubMed publication ID26509439
P5875ResearchGate publication ID283306100

P50authorLu-Ning LiuQ51779550
Joseph R SlupskyQ38322946
P2093author name stringNagesh Kalakonda
Mosavar Farahani
Carlos Rubbi
P2860cites workTrash or Treasure: extracellular microRNAs and cell-to-cell communicationQ21131238
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cellsQ24300024
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Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesisQ24307717
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesisQ24311780
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkersQ24614672
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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cellsQ27860960
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A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemiaQ28279141
Isolation and characterization of exosomes from cell culture supernatants and biological fluidsQ29615035
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory responseQ29615493
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Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesiclesQ29620600
AP-1: a double-edged sword in tumorigenesisQ30014831
Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemiaQ57234164
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosisQ57983943
Functional transfer of microRNA by exosomesQ83289821
Exosomes derived from Burkitt's lymphoma cell lines induce proliferation, differentiation, and class-switch recombination in B cellsQ30587658
Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometryQ31813987
Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progressionQ33706349
Exosome: from internal vesicle of the multivesicular body to intercellular signaling deviceQ34030873
MicroRNA profiling of follicular lymphoma identifies microRNAs related to cell proliferation and tumor responseQ34234677
MicroRNAs in human cancer: from research to therapyQ34630207
Exosomes as divine messengers: are they the Hermes of modern molecular oncology?Q34675263
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.Q34836437
MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation.Q34885097
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Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblastsQ35176121
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BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.Q36733492
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemiaQ36948708
Tumor stroma and regulation of cancer developmentQ37014752
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survivalQ37027816
Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemiaQ37188389
Exosome release by primary B cells.Q37524069
Exosomes: immune properties and potential clinical implementationsQ37822692
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Exosomes in tumor microenvironment influence cancer progression and metastasisQ38091978
How the microenvironment wires the natural history of chronic lymphocytic leukemiaQ38119790
The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: insight into disease biology and new targeted therapiesQ38135644
RNA trafficking by acute myelogenous leukemia exosomes.Q39245366
Cellular internalization of exosomes occurs through phagocytosisQ39742924
Induction of exosome release in primary B cells stimulated via CD40 and the IL-4 receptorQ39975624
Induction of heat shock proteins in B-cell exosomes.Q40392853
Adhesion and signaling by B cell-derived exosomes: the role of integrinsQ40570851
Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes.Q41369475
Targetome profiling, pathway analysis and genetic association study implicate miR-202 in lymphomagenesisQ41894251
MEC1 and MEC2: two new cell lines derived from B-chronic lymphocytic leukaemia in prolymphocytoid transformationQ42820324
Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cellsQ46058681
Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic targetQ46202182
miRWalk database for miRNA-target interactionsQ47991413
Variable induction of PRDM1 and differentiation in chronic lymphocytic leukemia is associated with anergy.Q48326557
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjecttranscriptomeQ252857
P304page(s)e0141429
P577publication date2015-10-28
P1433published inPLOS OneQ564954
P1476titleCLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p
P478volume10

Reverse relations

cites work (P2860)
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