Inhibition of fatty acid synthesis by expression of an acetyl-CoA carboxylase-specific ribozyme gene

scientific article published in October 1994

Inhibition of fatty acid synthesis by expression of an acetyl-CoA carboxylase-specific ribozyme gene is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1994PNAS...91.9951H
P356DOI10.1073/PNAS.91.21.9951
P932PMC publication ID44935
P698PubMed publication ID7937924
P5875ResearchGate publication ID15261161

P2093author name stringJ Ha
K H Kim
P2860cites workMeasurement of acetyl-CoA carboxylase activity in isolated hepatocytesQ69897457
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Cloning of human acetyl-CoA carboxylase cDNAQ28115261
Regulation of the Activity of Acetyl Coenzyme A Carboxylase by Palmitoyl Coenzyme A and CitrateQ28250037
Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active siteQ28301249
Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sitesQ28304694
Biological catalysis by RNA.Q30457173
The chemistry of self-splicing RNA and RNA enzymesQ30457285
Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotidesQ33635256
Structural features of the acetyl-CoA carboxylase gene: mechanisms for the generation of mRNAs with 5' end heterogeneityQ33865976
Specific gene suppression by engineered ribozymes in monkey cellsQ34321871
Molecular cloning of cDNA for acetyl-coenzyme A carboxylase.Q35052668
An enhancer element in the house-keeping promoter for acetyl-CoA carboxylase geneQ35843531
Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolatesQ35927204
Transcriptional regulation of acetyl coenzyme A carboxylase gene expression by tumor necrosis factor in 30A-5 preadipocytesQ36767429
Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cellsQ36834831
Fatty acylated proteins as components of intracellular signaling pathwaysQ37927014
Ribozyme mediated destruction of RNA in vivoQ40822323
Inhibition of SV40 replicon function by engineered antisense RNA transcribed by RNA polymerase III.Q41350334
Regulation of acetyl-CoA carboxylase gene expression. Insulin induction of acetyl-CoA carboxylase and differentiation of 30A5 preadipocytes require prior cAMP action on the geneQ41675423
Simple RNA enzymes with new and highly specific endoribonuclease activitiesQ43501578
Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideumQ44529739
Regulation of lipid synthesis in cultured animal cellsQ45159448
Ribozymes that cleave an RNA sequence from human immunodeficiency virus: the effect of flanking sequence on rateQ45853290
Mobile RNA catalystsQ45884231
Free fatty acids associated with the high molecular weight aminoacyl-tRNA synthetase complex influence its structure and function.Q47447838
Heterogeneity at the 5' end of rat acetyl-coenzyme A carboxylase mRNA. Lipogenic conditions enhance synthesis of a unique mRNA in liver.Q48297412
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirusQ48378635
Ribozymes correctly cleave a model substrate and endogenous RNA in vivo.Q50804065
Ribozymes as potential anti-HIV-1 therapeutic agents.Q54719925
A small catalytic oligoribonucleotideQ59060304
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectfatty acidQ61476
ribozymeQ205858
P304page(s)9951-9955
P577publication date1994-10-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInhibition of fatty acid synthesis by expression of an acetyl-CoA carboxylase-specific ribozyme gene
P478volume91

Reverse relations

cites work (P2860)
Q92999601Bta-miR-124a Affects Lipid Metabolism by Regulating PECR Gene
Q33886971Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes
Q37538048Efficient and specific ribozyme-mediated reduction of bovine alpha-lactalbumin expression in double transgenic mice
Q34837666Hammerhead ribozymes for target validation
Q28589371Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice
Q33969286Inhibition of acetyl coenzyme A carboxylase activity restores expression of the INO1 gene in a snf1 mutant strain of Saccharomyces cerevisiae
Q33923742Modification and repression of genes expressed in the mammary gland using gene targeting and other technologies
Q49334640Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease.
Q33798851Present and future studies on lipogenesis in animals and human subjects
Q40428287RNA cleavage by small catalytic RNAs
Q36802913The human histidine decarboxylase promoter is regulated by gastrin and phorbol 12-myristate 13-acetate through a downstream cis-acting element

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