Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection

scientific article published in January 1995

Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.69.1.93-100.1995
P932PMC publication ID188552
P698PubMed publication ID7983771

P2093author name stringY Huang
L Zhang
D D Ho
P2860cites workHow does HIV cause AIDS?Q22242244
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Importance of the nef gene for maintenance of high virus loads and for development of AIDSQ29618369
Human immunodeficiency virus type 1 negative factor is a transcriptional silencerQ33836630
Human immunodeficiency virus type 1 nef quasispecies in pathological tissueQ33934796
Structure of simian immunodeficiency virus regulatory genesQ34284560
Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1.Q34323971
Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitorQ34323995
Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replicationQ34603122
A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report from the Multicenter AIDS Cohort StudyQ34998944
Polymorphism of the 3' open reading frame of the virus associated with the acquired immune deficiency syndrome, human T-lymphotropic virus type III.Q35564616
The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophagesQ36362652
CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individualsQ36363328
Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.Q36633274
Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivoQ36650992
Evolution of human immunodeficiency virus type 1 nef and long terminal repeat sequences over 4 years in vivo and in vitroQ36687926
Highly localized tracks of human immunodeficiency virus type 1 Nef in the nucleus of cells of a human CD4+ T-cell lineQ36732916
Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIV (AGM).Q36800949
Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbersQ36801268
Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1Q36806618
Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolatesQ36827410
Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expressionQ36830303
Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA.Q37532727
Human immunodeficiency virus type 1 mRNA expression in peripheral blood cells predicts disease progression independently of the numbers of CD4+ lymphocytesQ37558815
Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals.Q40061126
The characterization of non-progressors: long-term HIV-1 infection with stable CD4+ T-cell levels.Q41531784
Effect of nef Alleles on Replication of Human Immunodeficiency Virus Type 1Q41558492
Effect of myristoylation on p27nef subcellular distribution and suppression of HIV-LTR transcriptionQ41635961
Differential effects of nef on HIV replication: implications for viral pathogenesis in the hostQ41757870
The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.Q41768724
Incubation period of AIDS in San FranciscoQ43953969
Rapid clinical and laboratory progression of HIV infectionQ44760004
Normal immune function and inability to isolate virus in culture in an individual with long-term human immunodeficiency virus type 1 infection.Q45780550
Quantitation of human immunodeficiency virus type 1 in the blood of infected personsQ45844274
Increasing viral burden in CD4+ T cells from patients with human immunodeficiency virus (HIV) infection reflects rapidly progressive immunosuppression and clinical diseaseQ45853529
Long-Term Human Immunodeficiency Virus Infection in Asymptomatic Homosexual and Bisexual Men with Normal CD4+ Lymphocyte Counts: Immunologic and Virologic CharacteristicsQ45860674
Natural HIV-1 NEF accelerates virus replication in primary human lymphocytesQ45866982
Polymorphic human gene(s) determines differential susceptibility of CD4 lymphocytes to infection by certain HIV-1 isolatesQ54195861
In vivo derived HIV-1 nef gene products are heterogeneous and lack detectable nucleotide binding activityQ54679703
Long-term symptomless HIV-1 infection in recipients of blood products from a single donorQ57076560
Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTRQ68097623
Summary of the epidemiology of HIV/AIDS in JapanQ72549557
P433issue1
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)93-100
P577publication date1995-01-01
P1433published inJournal of VirologyQ1251128
P1476titleCharacterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection
P478volume69

Reverse relations

cites work (P2860)
Q73358372A clearer distinction between HIV-1 paired isolates from peripheral blood mononuclear cells of asymptomatic carriers with and without CD8+ T-cells at nef rather than env V3 loci
Q28768294A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2.
Q24598018A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein
Q35699707APOBEC3G levels predict rates of progression to AIDS
Q21245213Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes
Q30176465Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
Q39872863Biological characterization of nef in long-term survivors of human immunodeficiency virus type 1 infection
Q36015423CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable
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Q30175327Conservation of the central proline-rich (PxxP) motifs of human immunodeficiency virus type 1 Nef protein during the disease progression in two hemophiliac patients
Q24336554Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
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Q35888785Genotypic and phenotypic characterization of long terminal repeat sequences from long-term survivors of human immunodeficiency virus type 1 infection.
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Q39595906The human immunodeficiency virus type 1 nef gene can to a large extent replace simian immunodeficiency virus nef in vivo.
Q35882911The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable.
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Q28647550The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase
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