Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer (scientific article published on 15 October 2014)

Association between severe treatment-related lymphopenia and progression-free survival in patients with newly diagnosed squamous cell head and neck cancer

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Radiochemotherapy induces a favourable tumour infiltrating inflammatory cell profile in head and neck cancer

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Effect of thymosin and irradiation on immune modulation in head and neck and esophageal cancer patients

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Effects of radiation therapy on T-lymphocyte subpopulations in patients with head and neck cancer

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Neoadjuvant therapy changes the lymphocyte composition of tumor-draining lymph nodes in cervical carcinoma

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Immunogenic tumor cell death induced by chemoradiotherapy in patients with esophageal squamous cell carcinoma

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Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial

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Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma?

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Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice

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Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial.

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Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products

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Immune suppression in premalignant respiratory papillomas: enriched functional CD4+Foxp3+ regulatory T cells and PD-1/PD-L1/L2 expression

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Programmed death ligand 2 in cancer-induced immune suppression.

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The abscopal effect associated with a systemic anti-melanoma immune response

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Role of T lymphocytes in tumor response to radiotherapy

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B7-H1 Expression Model for Immune Evasion in Human Papillomavirus-Related Oropharyngeal Squamous Cell Carcinoma

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Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing

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Cellular immune defect caused by postsurgical radiation therapy in patients with head and neck cancer

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Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis

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Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.

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Induction therapy in the modern era of combined-modality therapy for locally advanced head and neck cancer

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Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients.

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Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.

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HPV-induced oropharyngeal cancer, immune response and response to therapy

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Recognizing and reversing the immunosuppressive tumor microenvironment of head and neck cancer

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Radiation‐induced loss of cell surface CD47 enhances immune‐mediated clearance of human papillomavirus‐positive cancer

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Decreased HPV-specific T cell responses and accumulation of immunosuppressive influences in oropharyngeal cancer patients following radical therapy

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5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity

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Immune response during therapy with cisplatin or radiation for human papillomavirus-related head and neck cancer

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Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model.

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Serial studies of immunocompetence in head and neck cancer patients undergoing radiation therapy

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Effects of combined immunotherapy with levamisole and Bacillus Calmette-Guérin on immunocompetence of patients with squamous cell carcinoma of the cervix, head and neck, and lung undergoing radiation therapy

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Evidence for a Role of the PD-1:PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma

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Amifostine modulates radio-induced apoptosis of peripheral blood lymphocytes in head and neck cancer patients

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In SituObservation of the Effects of Local Irradiation on Cytotoxic and Regulatory T Lymphocytes in Cervical Cancer Tissue

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Increase of human papillomavirus-16 E7-specific T helper type 1 response in peripheral blood of cervical cancer patients after radiotherapy

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Selective changes in the immune profile of tumor-draining lymph nodes after different neoadjuvant chemoradiation regimens for locally advanced cervical cancer

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Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies

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The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy

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Long-term immune dysfunction after radiotherapy to the head and neck area

Q52006743

PD-1-Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

Q56965739

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

chemoradiotherapy

Q5090613

P304

page(s)

7205-7216

P577

publication date

2014-10-15

P1433

published in

Cancer Research

Q326097

P1476

title

Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer

P478

volume

Reverse relations

cites work (P2860)

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P356	DOI	10.1158/0008-5472.CAN-14-1913
P932	PMC publication ID	4498250
P698	PubMed publication ID	25320012