Tumour Necrosis Factor-α Gene Polymorphism Is Associated with Metastasis in Patients with Triple Negative Breast Cancer

scientific article published on 13 July 2015

Tumour Necrosis Factor-α Gene Polymorphism Is Associated with Metastasis in Patients with Triple Negative Breast Cancer is …
instance of (P31):
meta-analysisQ815382
scholarly articleQ13442814

External links are
P356DOI10.1038/SREP10244
P932PMC publication ID4499887
P698PubMed publication ID26165253
P5875ResearchGate publication ID280061727

P2093author name stringHui Zhu
Jie Li
Yong Huang
Jun Guo
Kan Zhai
Li-Sheng Liu
Zhe-Hai Wang
Hui-Hui Li
Chun-Xiao Chang
Xin-Ping Sun
P2860cites workGenetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF–LTA) and breast cancer riskQ57272107
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Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinomaQ73592380
Polymorphism in the tumor necrosis factor-alpha promotor region and in the heat shock protein 70 genes associated with malignant tumorsQ73807201
Association of breast cancer and polymorphisms of interleukin-10 and tumor necrosis factor-alpha genesQ79074326
Cytokine gene polymorphisms and breast cancer susceptibilityQ79685798
Body mass, polymorphisms in obesity-related genes, and the risk of developing breast cancer among women with benign breast diseaseQ80146358
Cytokine gene polymorphisms and breast cancer susceptibility and prognosisQ80361729
Increased risk of developing hepatocellular carcinoma associated with carriage of the TNF2 allele of the -308 tumor necrosis factor-alpha promoter geneQ80389256
Association of breast cancer and cytokine gene polymorphism in Turkish womenQ81510306
Polymorphism in the genes of alpha and beta tumor necrosis factors (TNF-alpha and TNF-beta) and gamma interferon (IFN-gamma) among Iranian women with breast cancerQ81741527
Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severityQ24806157
Cancer statistics, 2014Q27861018
SNPedia: a wiki supporting personal genome annotation, interpretation and analysisQ28740978
Weight gain, metabolic syndrome, and breast cancer recurrence: are dietary recommendations supported by the data?Q30572730
Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studiesQ33593016
Different role of tumor necrosis factor-α polymorphism in non-Hodgkin lymphomas among Caucasian and Asian populations: a meta-analysisQ33755625
Association of TNF-α, TNFRSF1A and TNFRSF1B gene polymorphisms with the risk of sporadic breast cancer in northeast Chinese Han womenQ33881968
Triple-negative breast cancer: clinical features and patterns of recurrenceQ34658655
Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancerQ35190079
Tumour necrosis factor alpha: a potential target for the therapy of solid tumours.Q35215812
Elevated pre-treatment levels of plasma C-reactive protein are associated with poor prognosis after breast cancer: a cohort studyQ35558075
Genomic structure, induction, and production of TNF-alphaQ35929510
Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activationQ36082965
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TNF-α gene knockout in triple negative breast cancer cell line induces apoptosisQ36589909
Transmembrane TNF-alpha mediates "forward" and "reverse" signaling, inducing cell death or survival via the NF-kappaB pathway in Raji Burkitt lymphoma cellsQ36838563
Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer.Q36994853
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Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patientsQ37280710
Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeuticsQ37764879
TNF-alpha polymorphisms and breast cancerQ37863045
Tumor necrosis factorQ38053787
Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancerQ39528651
TNF inhibitor suppresses bone metastasis in a breast cancer cell lineQ39574679
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer StudyQ39605778
Expression of TNF-alpha leader sequence renders MCF-7 tumor cells resistant to the cytotoxicity of soluble TNF-alphaQ39962698
The inflammatory cytokine tumor necrosis factor-alpha regulates chemokine receptor expression on ovarian cancer cellsQ40351465
Genetics of tumour necrosis factor-alpha in autoimmune, infectious, and neoplastic diseasesQ40428108
The tumor necrosis factor ligand and receptor families.Q40990575
The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription.Q41117030
Prognostic markers in triple-negative breast cancerQ42505075
Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer RegistryQ42510173
Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma.Q44117661
Targeting transmembrane TNF-α suppresses breast cancer growthQ46115142
Cytokine genotype polymorphisms in breast carcinoma: associations of TGF-beta1 with relapseQ46536358
Tumour necrosis factor alpha -308G/A polymorphism and risk of the four most frequent cancers: a meta-analysisQ46806146
Association between tumor necrosis factor in serum and cachexia in patients with prostate cancer.Q47794357
Tumor necrosis factor alpha and beta and interferon gamma gene polymorphisms in Turkish breast cancer patients.Q51504166
Association of the tumor necrosis factor-alpha -308G>A polymorphism with breast cancer in Mexican women.Q53080253
Role of ethnic variations in TNF-α and TNF-β polymorphisms and risk of breast cancer in India.Q53298412
TNF alpha promoter polymorphisms analysis in benign and malignant breast lesions.Q53337825
Polymorphisms of tumour necrosis factors A and B in breast cancer.Q53674100
Association of single nucleotide polymorphisms (SNPs) in TNF-LTA locus with breast cancer risk in Indian population.Q54537388
Tumour necrosis factor mediates E-selectin production and leukocyte accumulation in myocardial ischaemia-reperfusion injuryQ57222250
Polymorphisms in the BRCA1 and ABCB1 genes modulate menopausal hormone therapy associated breast cancer risk in postmenopausal womenQ57270560
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectTNFQ18032037
P304page(s)10244
P577publication date2015-07-13
P1433published inScientific ReportsQ2261792
P1476titleTumour Necrosis Factor-α Gene Polymorphism Is Associated with Metastasis in Patients with Triple Negative Breast Cancer
P478volume5

Reverse relations

cites work (P2860)
Q38726515Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells.
Q60960583Evaluation of pre-mir-34a rs72631823 single nucleotide polymorphism in triple negative breast cancer: A case-control study
Q88963822Genetic Modifiers of the Breast Tumor Microenvironment
Q41593437Genetic association between TNF-α promoter polymorphism and susceptibility to squamous cell carcinoma, basal cell carcinoma, and melanoma: A meta-analysis
Q47322786Graph-theoretical comparison of normal and tumor networks in identifying BRCA genes.
Q41709532Inflammatory factor TNF-α promotes the growth of breast cancer via the positive feedback loop of TNFR1/NF-κB (and/or p38)/p-STAT3/HBXIP/TNFR1.
Q46257711Nitro-fatty acid inhibition of triple negative breast cancer cell viability, migration, invasion and tumor growth
Q64093097Notch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast Cancer
Q38744343Overexpression of miR-509 Increases Apoptosis and Inhibits Invasion via Suppression of Tumor Necrosis Factor-α in Triple-Negative Breast Cancer Hs578T Cells
Q33757402TNF-α -308 A allele is associated with an increased risk of distant metastasis in rectal cancer patients from Southwestern China.
Q64118797Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer

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