Severe disturbance of glucose metabolism in peripheral blood mononuclear cells of schizophrenia patients: a targeted metabolomic study

scientific article published on 14 July 2015

Severe disturbance of glucose metabolism in peripheral blood mononuclear cells of schizophrenia patients: a targeted metabolomic study is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1005025299
P356DOI10.1186/S12967-015-0540-Y
P932PMC publication ID4501123
P698PubMed publication ID26169624
P5875ResearchGate publication ID280058735

P2093author name stringPeng Xie
Zhao Liu
Yi Xu
Ting Huang
Peng Zheng
Zheng Fang
Peng-Fei Cheng
Li-Bo Zhao
Xiao-Tong Zhang
Shun-Jie Bai
Mei-Ling Liu
Wei-Hua Shao
Xiang-Yu Du
Xue-Jiao Xu
Zhi-Guo Qi
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Gene expression profiling in treatment-naive schizophrenia patients identifies abnormalities in biological pathways involving AKT1 that are corrected by antipsychotic medicationQ44401758
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Morphine withdrawal produces circadian rhythm alterations of clock genes in mesolimbic brain areas and peripheral blood mononuclear cells in ratsQ46042359
Genome-wide expression analysis of peripheral blood identifies candidate biomarkers for schizophreniaQ46055055
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorderQ46767416
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Decreased plasma tryptophan and tryptophan/large neutral amino acid ratio in patients with neuroleptic-resistant schizophrenia: relationship to plasma cortisol concentrationQ48094042
Proteomic analysis reveals protein changes within layer 2 of the insular cortex in schizophrenia.Q48830689
Flow cytometric analysis of T cell subsets in paired samples of cerebrospinal fluid and peripheral blood from patients with neurological and psychiatric disorders.Q48938985
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytQ50309754
2,4-Dihydroxypyrimidine is a potential urinary metabolite biomarker for diagnosing bipolar disorder.Q50663896
Effects of age and sex on postprandial glucose metabolism: differences in glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction.Q51495641
Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action.Q51850457
Burden of care and general health in families of patients with schizophrenia.Q51924848
Age- and dose-dependent glucose-induced increases in memory and attention in schizophrenia.Q52029747
Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells.Q54280525
The use of the area under the ROC curve in the evaluation of machine learning algorithmsQ56594447
Impaired glycolytic response in peripheral blood mononuclear cells of first-onset antipsychotic-naive schizophrenia patientsQ60649880
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Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulationQ21260256
Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophreniaQ28469040
Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patientsQ30468799
Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes.Q33241006
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samplesQ33332023
Size of burden of schizophrenia and psychotic disordersQ33341221
Parallel changes in gene expression in peripheral blood mononuclear cells and the brain after maternal separation in the mouseQ33506763
Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology ConsortiumQ33902752
Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patientsQ34185951
Oxidative stress in schizophrenia: an integrated approachQ34494844
Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia.Q34911118
Analysis of whole genome biomarker expression in blood and brainQ34994239
Changes in BMI, duration of overweight and obesity, and glucose metabolism: 45 years of follow-up of a birth cohortQ35179968
Identification and validation of urinary metabolite biomarkers for major depressive disorderQ36508139
Metabolomics tools for identifying biomarkers for neuropsychiatric diseasesQ37419784
Revisiting the diagnosis of schizophrenia: where have we been and where are we going?Q37825634
Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophreniaQ43062918
The comparison of glycometabolism parameters and lipid profiles between drug-naïve, first-episode schizophrenia patients and healthy controlsQ44091620
P921main subjectschizophreniaQ41112
P304page(s)226
P577publication date2015-07-14
P1433published inJournal of Translational MedicineQ15716664
P1476titleSevere disturbance of glucose metabolism in peripheral blood mononuclear cells of schizophrenia patients: a targeted metabolomic study
P478volume13

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cites work (P2860)
Q64283871Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder
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Q89507956Diagnosis of major depressive disorder based on changes in multiple plasma neurotransmitters: a targeted metabolomics study
Q26752342Dopamine-prolactin pathway potentially contributes to the schizophrenia and type 2 diabetes comorbidity
Q59335564Is It Possible to Predict the Future in First-Episode Psychosis?
Q47642189Metabolite identification in fecal microbiota transplantation mouse livers and combined proteomics with chronic unpredictive mild stress mouse livers
Q36743314Metabolomic Profiling of Post-Mortem Brain Reveals Changes in Amino Acid and Glucose Metabolism in Mental Illness Compared with Controls
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Q92292838Systemic Immuno-metabolic alterations in chronic obstructive pulmonary disease (COPD)

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