The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions

scientific article published on 24 November 2015

The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1005288
P932PMC publication ID4658056
P698PubMed publication ID26599541
P5875ResearchGate publication ID284711804

P50authorNoam Stern-GinossarQ83239112
Mirko TrillingQ39051155
Vu Thuy Khanh LeQ39051170
P2093author name stringGilgi Friedlander
Alina Shitrit
Marvin Tanenbaum
Odem Shani
Osnat Tirosh
Yifat Cohen
P2860cites workEWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamilyQ24291564
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Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141Q28546343
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosolQ29618773
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Regulation of the translation initiation factor eIF4F by multiple mechanisms in human cytomegalovirus-infected cellsQ33843314
Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAsQ33870381
An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirusQ33904045
Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysisQ34014646
Synthesis of the translational apparatus is regulated at the translational levelQ34058830
HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cellsQ34116205
Ribosome profiling reveals pervasive translation outside of annotated protein-coding genesQ34435177
Human cytomegalovirus infection dysregulates the canonical Wnt/β-catenin signaling pathwayQ34446646
ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic StressQ34620780
Upregulation of Nrf2 expression by human cytomegalovirus infection protects host cells from oxidative stress.Q44506954
Virus assay methods: accuracy and validationQ45752919
The human cytomegalovirus genome revisited: comparison with the chimpanzee cytomegalovirus genomeQ48264323
Evaluation of the host transcriptional response to human cytomegalovirus infection.Q51597552
Cytoskeletal disruption during human cytomegalovirus infection of human lung fibroblasts.Q52489789
Transcriptome analysis of fibroblast cells immediate-early after human cytomegalovirus infectionQ73313684
Immunocytochemical reorganization of the nucleolus in human embryo fibroblasts infected with cytomegalovirus in vitroQ78956804
DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replicationQ35531558
Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translationQ35820844
A unifying model for mTORC1-mediated regulation of mRNA translation.Q35945036
Cytomegalovirus destruction of focal adhesions revealed in a high-throughput Western blot analysis of cellular protein expression.Q35947629
Regulation of mRNA translation during mitosisQ35992687
Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivityQ36119693
Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B.Q36295396
Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arraysQ36736217
The translational landscape of mTOR signalling steers cancer initiation and metastasisQ36873513
Mechanisms, biology and inhibitors of deubiquitinating enzymesQ36975731
Reevaluation of human cytomegalovirus coding potential.Q37089601
Subversion of cell cycle regulatory pathwaysQ37219997
Cytomegalovirus immune evasion.Q37220012
Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complexQ37380692
Cleavage specificity of the UL48 deubiquitinating protease activity of human cytomegalovirus and the growth of an active-site mutant virus in cultured cellsQ37452085
Synthesis of Proteins and Glycoproteins in Cells Infected with Human CytomegalovirusQ37506885
The Paf1 complex: platform or player in RNA polymerase II transcription?Q37671309
Rho-associated coiled-coil kinase (ROCK) signaling and diseaseQ38100279
Emerging roles of RNA modification: m(6)A and U-tailQ38244608
Cdc37 as a co-chaperone to Hsp90.Q38285298
The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN.Q38298607
The translational landscape of the mammalian cell cycleQ38350351
Global reprogramming of the cellular translational landscape facilitates cytomegalovirus replicationQ38617359
Altered microRNA expression after infection with human cytomegalovirus leads to TIMP3 downregulation and increased shedding of metalloprotease substrates, including MICA.Q38980178
EWI-2 association with α-actinin regulates T cell immune synapses and HIV viral infection.Q39332714
The cytomegaloviral protein pUL138 acts as potentiator of tumor necrosis factor (TNF) receptor 1 surface density to enhance ULb'-encoded modulation of TNF-α signalingQ39462585
Human cytomegalovirus stimulates host cell RNA synthesisQ39918957
Global analysis of host cell gene expression late during cytomegalovirus infection reveals extensive dysregulation of cell cycle gene expression and induction of Pseudomitosis independent of US28 functionQ40213794
Inactivation of Thirty Viruses by Gamma RadiationQ40716309
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.Q40900792
Dynamic Co-evolution of Host and Pathogen: HCMV Downregulates the Prevalent Allele MICA∗008 to Escape Elimination by NK CellsQ41482457
Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcriptionQ41905953
Herpes simplex virus type 1 preferentially targets human colon carcinoma: role of extracellular matrix.Q41914618
Co-opting the Fanconi anemia genomic stability pathway enables herpesvirus DNA synthesis and productive growthQ42210707
All translation elongation factors and the e, f, and h subunits of translation initiation factor 3 are encoded by 5'-terminal oligopyrimidine (TOP) mRNAsQ42418718
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectcytomegaloviral diseaseQ2076966
P304page(s)e1005288
P577publication date2015-11-24
P1433published inPLOS PathogensQ283209
P1476titleThe Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions
P478volume11

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