Novel HDL-directed pharmacotherapeutic strategies

scientific article published on 18 January 2011

Novel HDL-directed pharmacotherapeutic strategies is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/NRCARDIO.2010.200
P932PMC publication ID3315102
P698PubMed publication ID21243009
P5875ResearchGate publication ID49763128

P2093author name stringDaniel J Rader
Emil M Degoma
P2860cites workA novel endothelial-derived lipase that modulates HDL metabolismQ22009153
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophagesQ24320180
HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathwayQ24323992
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoterQ24550969
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbetaQ24598068
Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in miceQ24600864
Safety and tolerability of dalcetrapib (RO4607381/JTT-705): results from a 48-week trialQ24648125
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient miceQ24681140
Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosisQ24812868
Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trialQ28181984
Molecular identification of high and low affinity receptors for nicotinic acidQ28202556
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effectQ28206812
Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response studyQ28216693
Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trialQ28236480
Design of the DEFINE trial: determining the EFficacy and tolerability of CETP INhibition with AnacEtrapibQ28259638
Functional lecithin: cholesterol acyltransferase is not required for efficient atheroprotection in humansQ43290558
High-dose recombinant apolipoprotein A-I(milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein e-deficient mice. Potential implications for acute plaque stabilizationQ43653251
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alphaQ28273937
Nicotinic acid receptor agonists differentially activate downstream effectorsQ28298974
Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patientsQ28308033
Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtypeQ28511354
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoEQ28513193
Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targetingQ28584943
Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipidsQ28752575
Effects of torcetrapib in patients at high risk for coronary eventsQ29619609
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptorQ30881181
Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population studyQ33577884
Randomized Evaluation of the Effects of Anacetrapib through Lipid-modification (REVEAL)-A large-scale, randomized, placebo-controlled trial of the clinical effects of anacetrapib among people with established vascular disease: Trial design, [...]Q33643426
A randomized trial of therapies for type 2 diabetes and coronary artery diseaseQ33827504
Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophagesQ33929735
Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda studyQ33942742
Lecithin-cholesterol acyltransferase: role in lipoprotein metabolism, reverse cholesterol transport and atherosclerosisQ33959456
Influence of nicotinic acid on serum cholesterol in man.Q33972172
Bone marrow transplantation shows superior atheroprotective effects of gene therapy with apolipoprotein A-I Milano compared with wild-type apolipoprotein A-I in hyperlipidemic miceQ33982567
Seeing red: flushing out instigators of niacin-associated skin toxicity.Q34028776
Structure/function relationships of apolipoprotein a-I mimetic peptides: implications for antiatherogenic activities of high-density lipoprotein.Q34144449
Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteinsQ34170352
Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacinQ34190482
Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbitQ34248584
A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in miceQ34559952
Optimal medical therapy with or without PCI for stable coronary diseaseQ34612445
Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivoQ34828796
Endothelial lipase is a major determinant of HDL levelQ34829121
Endothelial lipase: a new lipase on the blockQ34981113
Molecular regulation of HDL metabolism and function: implications for novel therapiesQ35191066
The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL.Q35732501
Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extentQ35793779
Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approachesQ35860029
Antiinflammatory properties of HDL.Q35919164
Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patientsQ36662681
Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptideQ43664811
Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary diseaseQ43834212
Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterolQ43862770
Recombinant apolipoprotein A-I(Milano) infusion into rabbit carotid artery rapidly removes lipid from fatty streaks.Q43997276
Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention TrialQ44063968
Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivoQ44090023
Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trialQ44783935
High density lipoprotein plasma fractions inhibit aortic fatty streaks in cholesterol-fed rabbitsQ44982506
Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with staQ45146790
Flushing profile of extended-release niacin/laropiprant versus gradually titrated niacin extended-release in patients with dyslipidemia with and without ischemic cardiovascular disease.Q45940733
Reconstituted high-density lipoprotein increases plasma high-density lipoprotein anti-inflammatory properties and cholesterol efflux capacity in patients with type 2 diabetes.Q46090651
Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient miceQ46153586
Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitorsQ46212716
Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of AtheroscQ46231225
Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque.Q46333846
Effectiveness of inhibition of cholesteryl ester transfer protein by JTT-705 in combination with pravastatin in type II dyslipidemiaQ46447595
D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null miceQ46450296
Compromised LCAT function is associated with increased atherosclerosisQ46630196
Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1-palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: in vivo assessment by intravascular ultrasound and magnetic resonaQ46701074
Endothelial lipase is increased in vivo by inflammation in humansQ46796575
Apolipoprotein A-I and the molecular variant apoA-I(Milano): evaluation of the antiatherogenic effects in knock-in mouse model.Q46802379
Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studiesQ46858990
Protective effect of an endothelial lipase gene variant on coronary artery disease in a Chinese populationQ46911886
Illuminating HDL--is it still a viable therapeutic target?Q46913574
ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysisQ47748338
Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbetaQ47884555
High plasma cholesteryl ester transfer protein levels may favour reduced incidence of cardiovascular events in men with low triglycerides.Q51473820
Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The Canadian Coronary Atherosclerosis Intervention Trial.Q51596506
Differential effects of apolipoprotein A-I-mimetic peptide on evolving and established atherosclerosis in apolipoprotein E-null mice.Q51620237
Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL.Q53569234
Functional Lecithin: Cholesterol Acyltransferase Is Not Required for Efficient Atheroprotection in HumansQ59275772
Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic miceQ64381105
Production and characterization of a reconstituted high density lipoprotein for therapeutic applicationsQ71766897
Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels. The Regression Growth Evaluation Statin Study (REGRESS)Q72220309
Large and cholesteryl ester-rich high-density lipoproteins in cholesteryl ester transfer protein (CETP) deficiency can not protect macrophages from cholesterol accumulation induced by acetylated low-density lipoproteinsQ72410988
Recombinant apolipoprotein A-I Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbitsQ72711480
Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevityQ73440398
Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: the Framingham studyQ73783104
Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transportQ73832914
Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbitsQ74230827
Causes of interscan variability of coronary artery calcium measurements at electron-beam CTQ74290724
Vaccine-induced antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit model of atherosclerosisQ74290884
Increased cholesterol efflux potential of sera from ApoA-IMilano carriers and transgenic miceQ77739504
Wild-type ApoA-I and the Milano variant have similar abilities to stimulate cellular lipid mobilization and effluxQ80576677
Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transportQ80819953
Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbitsQ81553526
Apolipoprotein A-I mimetic peptidesQ82957586
An increased coronary risk is paradoxically associated with common cholesteryl ester transfer protein gene variations that relate to higher high-density lipoprotein cholesterol: a population-based studyQ83309967
A first-in-man, randomized, placebo-controlled study to evaluate the safety and feasibility of autologous delipidated high-density lipoprotein plasma infusions in patients with acute coronary syndromeQ84384910
Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosteroneQ36736504
Structural requirements for antioxidative and anti-inflammatory properties of apolipoprotein A-I mimetic peptidesQ36850018
Liver X receptor and farnesoid X receptor as therapeutic targetsQ37019321
Effects of Nicotinic Acid Therapy on Plasma High Density Lipoprotein Subfraction Distribution and Composition and on Apolipoprotein A MetabolismQ37038074
High Density Lipoprotein Metabolism in ManQ37047273
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humansQ37143381
Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivoQ37151837
Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary riskQ37193386
Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosisQ37253754
Cholesteryl ester transfer protein (CETP) inhibitors: is there life after torcetrapib?Q37301808
The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populationsQ37323099
Liver X receptor modulators: effects on lipid metabolism and potential use in the treatment of atherosclerosisQ37356255
Extended-release niacin alters the metabolism of plasma apolipoprotein (Apo) A-I and ApoB-containing lipoproteinsQ37386911
Lecithin: cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivoQ37485026
The pharmacology and off-target effects of some cholesterol ester transfer protein inhibitorsQ37628885
Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosisQ38356091
Reconstituted high-density lipoprotein attenuates platelet function in individuals with type 2 diabetes mellitus by promoting cholesterol effluxQ38377760
Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trialQ38398332
D-4F, an apolipoprotein A-I mimetic peptide, promotes cholesterol efflux from macrophages via ATP-binding cassette transporter A1.Q39731327
Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivoQ39746656
An apoA-I mimetic peptide facilitates off-loading cholesterol from HDL to liver cells through scavenger receptor BI.Q39784725
Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbitsQ40166036
Vaccinating rabbits with a cholesteryl ester transfer protein (CETP) B-Cell epitope carried by heat shock protein-65 (HSP65) for inducing anti-CETP antibodies and reducing aortic lesions in vivoQ40422178
Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population studyQ40486175
The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1cQ40524290
Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor.Q40658862
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particlesQ40720835
A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbitsQ40866383
Reconstituted HDL containing human apolipoprotein A-1 reduces VCAM-1 expression and neointima formation following periadventitial cuff-induced carotid injury in apoE null miceQ41697403
Serial quantitative coronary angiography and coronary eventsQ41737961
L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregationQ41817158
Anti-inflammatory apoA-I-mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I.Q41829964
Macrophage reverse cholesterol transport in mice expressing ApoA-I MilanoQ41855576
Intestinal ABCA1 directly contributes to HDL biogenesis in vivoQ41896773
Biochemical characterization of cholesteryl ester transfer protein inhibitorsQ42107210
Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transportQ42126715
Lecithin: cholesterol acyltransferase and atherosclerosis: another high-density lipoprotein story that doesn't quite follow the scriptQ42540496
Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapibQ42562376
Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humansQ42752695
Emerging high-density lipoprotein infusion therapies: fulfilling the promise of epidemiology?Q42788509
Safety of Anacetrapib in Patients with or at High Risk for Coronary Heart DiseaseQ42807626
Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosisQ42950549
RVX-208: a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivoQ43049803
Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT.Q43064370
The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duraQ43095846
Lessons learned from the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events (ILLUMINATE) trialQ43246793
High plasma lecithin:cholesterol acyltransferase activity does not predict low incidence of cardiovascular events: possible attenuation of cardioprotection associated with high HDL cholesterolQ43287987
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)266-277
P577publication date2011-01-18
P1433published inNature Reviews CardiologyQ2108444
P1476titleNovel HDL-directed pharmacotherapeutic strategies
P478volume8

Reverse relations

cites work (P2860)
Q37416464A common functional promoter variant links CNR1 gene expression to HDL cholesterol level
Q36709656A novel approach to oral apoA-I mimetic therapy
Q37056843APO A2 -265T/C Polymorphism Is Associated with Increased Inflammatory Responses in Patients with Type 2 Diabetes Mellitus.
Q34950045Anticipatory role of high density lipoprotein and endothelial dysfunction: an overview
Q38732861ApoE controls the interface linking lipids and inflammation in atherosclerosis
Q92372987Apolipoprotein A-I (ApoA-I), Immunity, Inflammation and Cancer
Q37957869Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis
Q34221770Apolipoprotein A-I attenuates palmitate-mediated NF-κB activation by reducing Toll-like receptor-4 recruitment into lipid rafts
Q37688597Apolipoprotein A1: a novel serum biomarker for predicting the prognosis of hepatocellular carcinoma after curative resection
Q36293610Approach to the patient with extremely low HDL-cholesterol
Q35800550Association of a Human FABP1 Gene Promoter Region Polymorphism with Altered Serum Triglyceride Levels
Q35879603Atherosclerosis
Q64079430Characterization of apolipoprotein A-I peptide phospholipid interaction and its effect on HDL nanodisc assembly
Q58804822Creatine kinase, energy reserve, and hypertension: from bench to bedside
Q35917056Crosstalk between reverse cholesterol transport and innate immunity
Q37702199Current guidelines for high-density lipoprotein cholesterol in therapy and future directions.
Q34718513Decrease in irisin in patients with chronic kidney disease
Q38706633Deficiency of Cholesteryl Ester Transfer Protein Protects Against Atherosclerosis in Rabbits
Q38848673Detection and treatment of atherosclerosis using nanoparticles
Q39427274Dietary Strategies and Novel Pharmaceutical Approaches Targeting Serum ApoA-I Metabolism: A Systematic Overview
Q38127103Dietary approaches to improving atheroprotective HDL functions
Q63560435Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
Q39771997Endothelial lipase inhibitors for the treatment of atherosclerosis and cardiovascular disorders
Q41771811Expressed protein ligation-mediated template protein extension
Q34429737Functional characterization of newly-discovered mutations in human SR-BI
Q37667665Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI: an old dog with new tricks
Q24603711Functionally defective high-density lipoprotein and paraoxonase: a couple for endothelial dysfunction in atherosclerosis
Q36344509Gene Therapy Targeting LDL Cholesterol but not HDL Cholesterol Induces Regression of Advanced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia
Q30275688Genetic variants in CETP increase risk of intracerebral hemorrhage
Q38240748HDL and cardiovascular disease
Q36918309HDL, Atherosclerosis, and Emerging Therapies
Q46866176HDL--is it too big to fail?
Q38087383HDL-C: clinical equipoise and vascular endothelial function
Q36150462High Density Lipoprotein and it's Dysfunction
Q91975923High Density Lipoproteins: Metabolism, Function, and Therapeutic Potential
Q26775420High density lipoproteins: Measurement techniques and potential biomarkers of cardiovascular risk
Q37996363High-density lipoprotein and atherosclerosis: the role of antioxidant activity
Q43498643High-density lipoprotein cholesterol targeting for novel drug discovery: where have we gone wrong?
Q38506490High-density lipoprotein-based drug discovery for treatment of atherosclerosis
Q36903963Human apolipoprotein A-II protects against diet-induced atherosclerosis in transgenic rabbits
Q38066291Hypercholesterolemia links hematopoiesis with atherosclerosis.
Q37298694Implication of low HDL-c levels in patients with average LDL-c levels: a focus on oxidized LDL, large HDL subpopulation, and adiponectin.
Q49757235Improved survival rate after myocardial infarction using an inducible cholesterol efflux (iCE) peptide: FAMP.
Q50621714Increased Hepatic Expression of Endothelial Lipase Inhibits Cholesterol Diet-Induced Hypercholesterolemia and Atherosclerosis in Transgenic Rabbits.
Q35811972Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport
Q36141666Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial
Q35606800Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.
Q37556042Lipid-Free Apolipoprotein A-I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio.
Q38857349Metabolic regulation of magnolol on the nuclear receptor, liver X receptor
Q37650114Micro-RNAs and High-Density Lipoprotein Metabolism.
Q60675346MicroRNAs regulating lipid metabolism in atherogenesis
Q38125279Molecular biology of atherosclerosis
Q36037988Molecular mechanisms of vascular effects of High-density lipoprotein: alterations in cardiovascular disease
Q37671683Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis
Q37123887Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex
Q27002774Niacin, an old drug with a new twist
Q26823249Novel therapies focused on the high-density lipoprotein particle
Q30455490Perspectives and opportunities for nanomedicine in the management of atherosclerosis.
Q37695401Pharmacogenomics of high-density lipoprotein-cholesterol-raising therapies.
Q52647946Potential role of new molecular plasma signatures on cardiovascular risk stratification in asymptomatic individuals.
Q55173600Preoperative serum apolipoprotein A-I levels predict long-term survival in non-muscle-invasive bladder cancer patients.
Q33972551Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey
Q21132391RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist
Q38003957Rationale for cholesteryl ester transfer protein inhibition
Q36443768Reducing vascular events risk in patients with dyslipidaemia: an update for clinicians
Q35626943Regulation of ABCA1 functions by signaling pathways
Q31064738Substituted benzamides containing azaspiro rings as upregulators of apolipoprotein A-I transcription.
Q35974993Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein
Q42096573The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism
Q28388695The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects
Q38896299The role of HDL in plaque stabilization and regression: basic mechanisms and clinical implications
Q48175299The role of monocytosis and neutrophilia in atherosclerosis
Q36808201Vascular disease and dementias: paradigm shifts to drive research in new directions
Q83276925[HDL level or HDL function as the primary target in preventive cardiology]
Q37709886microRNAs in lipoprotein metabolism and cardiometabolic disorders.

Search more.