Surface APRIL Is Elevated on Myeloid Cells and Is Associated with Disease Activity in Patients with Rheumatoid Arthritis

scientific article published in March 2015

Surface APRIL Is Elevated on Myeloid Cells and Is Associated with Disease Activity in Patients with Rheumatoid Arthritis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3899/JRHEUM.140630
P932PMC publication ID4506783
P698PubMed publication ID25729037

P2093author name stringJennifer Gonzalez
Kimberly J Payne
Ioana Moldovan
Elvin A Hernandez
Keith Colburn
Abigail Benitez
Andrea Parra
Abby Jones Weldon
Sheri Hsu
Marven G Cabling
Nasim Daoud
P2860cites workTACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune diseaseQ22254041
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88Q24293739
Adipocytes as immune cells: differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue developmentQ24336188
Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertaseQ24522584
An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion proteinQ24539012
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritisQ27860872
BAFF, APRIL and their receptors: structure, function and signalingQ28258238
Toll-like receptor 9, transmembrane activator and calcium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B-cell activationQ30425171
Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway.Q33193186
Infiltrations of plasma cells in synovium are highly associated with synovial fluid levels of APRIL in inflamed peripheral joints of rheumatoid arthritisQ33387629
BLyS and APRIL in rheumatoid arthritisQ34084521
Cell to Cell Interaction Can Activate Membrane-bound APRIL Which Are Expressed on Inflammatory MacrophagesQ34362023
Moving towards a cure: blocking pathogenic antibodies in systemic lupus erythematosus.Q34753885
BAFF AND APRIL: a tutorial on B cell survivalQ34994661
The role of B cells in rheumatoid arthritis: mechanisms and therapeutic targetsQ35111838
Mechanisms of B cell autoimmunity in SLE.Q35840704
The design and characterization of receptor-selective APRIL variantsQ36347872
Fractalkine preferentially mediates arrest and migration of CD16+ monocytesQ36370923
APRIL, a proliferation-inducing ligand, as a potential marker of lupus nephritisQ36907709
Anticytokine therapy impacting on B cells in autoimmune diseasesQ37433729
Macrophages express membrane bound form of APRIL that can generate immunomodulatory signalsQ39697425
A proliferation-inducing ligand (APRIL) is expressed by astrocytes and is increased in multiple sclerosisQ40185060
Pharmacokinetics, pharmacodynamics, and tolerability of single ascending doses of RCT-18 in Chinese patients with rheumatoid arthritisQ41758222
Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptorsQ42101285
A role for BLyS in the activation of innate immune cellsQ42742005
The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF.Q43925988
Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF.Q44280905
Expression of Fcgamma and complement receptors on peripheral blood monocytes in systemic lupus erythematosus and rheumatoid arthritisQ44745341
Specific TLR ligands regulate APRIL secretion by dendritic cells in a PKR-dependent mannerQ44885882
Expressions of BAFF/BAFF receptors and their correlation with disease activity in Chinese SLE patientsQ45285288
Inflammatory immune cell responses and Toll-like receptor expression in synovial tissues in rheumatoid arthritis patients treated with biologics or DMARDsQ46055310
Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: results of a phase II, randomized, placebo-controlled, dose-finding trialQ46071397
Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritisQ46397162
BAFF and TACI gene expression are increased in patients with untreated very early rheumatoid arthritisQ46466905
Elevated BAFF (BLyS) and APRIL in Juvenile idiopathic arthritis patients: relation to clinical manifestations and disease activity.Q46511708
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.Q47365613
Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritisQ47596885
Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsetsQ48649134
Human cartilage gp-39+,CD16+ monocytes in peripheral blood and synovium: correlation with joint destruction in rheumatoid arthritisQ49075645
Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow.Q51005962
Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival.Q51640866
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL.Q51966554
In vitro and in vivo activation induces BAFF and APRIL expression in B cells.Q52922658
CD14+,CD16+ blood monocytes and joint inflammation in rheumatoid arthritisQ78387171
Recruitment of CD16+ monocytes into synovial tissues is mediated by fractalkine and CX3CR1 in rheumatoid arthritis patientsQ80243459
Rheumatoid arthritis fibroblast-like synoviocytes express BCMA and are stimulated by APRILQ81517209
The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell populationQ82065955
Raised serum level of APRIL in patients with systemic lupus erythematosus: correlations with disease activity indicesQ82706275
Heterogeneity of human monocytes: an optimized four-color flow cytometry protocol for analysis of monocyte subsetsQ83393584
Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase II, randomized, placebo-controlled trialQ83753641
The classical CD14⁺⁺ CD16⁻ monocytes, but not the patrolling CD14⁺ CD16⁺ monocytes, promote Th17 responses to Candida albicansQ84417973
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
P304page(s)749-759
P577publication date2015-03-01
P1433published inThe Journal of RheumatologyQ7743623
P1476titleSurface APRIL Is Elevated on Myeloid Cells and Is Associated with Disease Activity in Patients with Rheumatoid Arthritis
P478volume42

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cites work (P2860)
Q39573678Differential in vivo activation of monocyte subsets during low-grade inflammation through experimental endotoxemia in humans.
Q33730611Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS.
Q92088693Serum proteome profiles to differentiate Crohn disease from intestinal tuberculosis and primary intestinal lymphoma: A pilot study
Q36820353Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury.

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