A Single-Cell Gene-Expression Profile Reveals Inter-Cellular Heterogeneity within Human Monocyte Subsets

scientific article published on 9 December 2015

A Single-Cell Gene-Expression Profile Reveals Inter-Cellular Heterogeneity within Human Monocyte Subsets is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1044351G
P356DOI10.1371/JOURNAL.PONE.0144351
P932PMC publication ID4674153
P698PubMed publication ID26650546
P5875ResearchGate publication ID286444562

P50authorSabina JanciauskieneQ47158764
P2093author name stringOlof Grip
Thomas B Rasmussen
Katarina Håkansson
Jens G Gerwien
Susanne T Gren
P2860cites workBlood monocytes: development, heterogeneity, and relationship with dendritic cellsQ24314793
Single-cell dissection of transcriptional heterogeneity in human colon tumorsQ24628796
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cellsQ29617430
Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsetsQ33497611
Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell developmentQ34049333
Nomenclature of monocytes and dendritic cells in blood.Q34125860
The novel subset of CD14+/CD16+ blood monocytes is expanded in sepsis patientsQ34306860
Identification and characterization of a novel monocyte subpopulation in human peripheral blood.Q34418064
Plasticity of CD4+ T cell lineage differentiation.Q34982725
A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionalityQ35583278
Adhesion mechanisms regulating the migration of monocytesQ35790360
Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogenyQ36263627
Fractalkine preferentially mediates arrest and migration of CD16+ monocytesQ36370923
The CD16(+) (FcgammaRIII(+)) subset of human monocytes preferentially becomes migratory dendritic cells in a model tissue settingQ36376577
SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subsetQ38487146
Single cell transcriptional analysis reveals novel innate immune cell typesQ41829357
Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptorsQ42101285
Reprint of: Monocyte subsets in man and other speciesQ44885390
TL1A synergizes with IL-12 and IL-18 to enhance IFN-gamma production in human T cells and NK cellsQ47578714
Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsetsQ48649134
Increased subpopulations of CD16(+) and CD56(+) blood monocytes in patients with active Crohn's disease.Q53574395
CD14(hi)HLA-DR(dim) macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohn's disease.Q54629123
Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation.Q54778607
Transcription and enhancer profiling in human monocyte subsetsQ56879936
CD14+,CD16+ blood monocytes and joint inflammation in rheumatoid arthritisQ78387171
IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversityQ81434870
The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell populationQ82065955
Increased frequency and cell death of CD16+ monocytes with Mycobacterium tuberculosis infectionQ84214847
CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney diseaseQ85189304
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectheterogeneityQ928498
P304page(s)e0144351
P577publication date2015-12-09
P1433published inPLOS OneQ564954
P1476titleA Single-Cell Gene-Expression Profile Reveals Inter-Cellular Heterogeneity within Human Monocyte Subsets
P478volume10

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cites work (P2860)
Q96766149COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis
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Q90208236Identification of Novel Human Monocyte Subsets and Evidence for Phenotypic Groups Defined by Interindividual Variations of Expression of Adhesion Molecules
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Q90583148Integrating -Omics Approaches into Human Population-Based Studies of Prenatal and Early-Life Exposures
Q98158482Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities
Q64889510Monocyte NOTCH2 expression predicts IFN-β immunogenicity in multiple sclerosis patients.
Q57174140Monocyte Subsets: Phenotypes and Function in Tuberculosis Infection
Q64987946PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia.
Q38848938Role of Monocytes and Intestinal Macrophages in Crohn's Disease and Ulcerative Colitis
Q50119083Role of Monocytes in Heart Failure and Atrial Fibrillation
Q40292577Scavenger Receptor MARCO Orchestrates Early Defenses and Contributes to Fungal Containment during Cryptococcal Infection.
Q47445787Single-cell RNA sequencing reveals developmental heterogeneity among early lymphoid progenitors
Q41497268The MHC class II antigen presentation pathway in human monocytes differs by subset and is regulated by cytokines

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