The interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids

scientific article published in April 2012

The interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1089/NAT.2012.0342
P932PMC publication ID3317788
P698PubMed publication ID22480315
P5875ResearchGate publication ID223961886

P2093author name stringYalin Tang
Xiaohui Ji
Junfeng Xiang
Changqi Zhao
Hongxia Sun
Huaxi Zhou
P2860cites workDirect evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcriptionQ24535577
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Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4Q36360588
Helix formation by guanylic acidQ36397431
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The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivoQ38359848
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A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogeneQ42108961
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Gene function correlates with potential for G4 DNA formation in the human genomeQ43056206
Perylene diimides with different side chains are selective in inducing different G-quadruplex DNA structures and in inhibiting telomeraseQ44105397
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Polyethylenimine effectively induces, stabilizes, and regulates intramolecular G-quadruplexes.Q45930248
Stabilizing parallel G-quadruplex DNA by a new class of ligands: two non-planar alkaloids through interaction in lateral groovesQ46076495
Fast screening and structural elucidation of G-quadruplex ligands from a mixture via G-quadruplex recognition and NMR methodsQ46241593
Ligand binding to tandem G quadruplexes from human telomeric DNA.Q46315894
1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomeraseQ47690130
Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivoresQ48820869
The interaction of telomere DNA G-quadruplex with three bis-benzyltetrahydroisoquinoline alkaloids.Q53211455
Interaction of cationic porphyrins with DNA.Q54045052
Inducement of G-quadruplex DNA forming and down-regulation of oncogene c-myc by bile acid-amino acid conjugate-BAA.Q54431566
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Stabilization of G-Quadruplex DNA and Inhibition of Telomerase Activity by Square-Planar Nickel(II) ComplexesQ60463184
Folkloric Medicinal Plants:Tinospora sagittatavar.cravanianaandMahonia bealeiQ67870180
Selective inhibition of telomerase activity during terminal differentiation of immortal cell linesQ71254294
Structural polymorphism of telomere DNA: interquadruplex and duplex-quadruplex conversions probed by Raman spectroscopyQ72015636
Duplex to quadruplex equilibrium of the self-complementary oligonucleotide d(GGGGCCCC)Q72278105
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Sequence and structural selectivity of nucleic acid binding ligandsQ73248196
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Characterization and thermodynamic properties of quadruplex/duplex competitionQ74709869
Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-dionesQ77580646
Berberine-induced apoptosis of human leukemia HL-60 cells is associated with down-regulation of nucleophosmin/B23 and telomerase activityQ77853485
Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cellsQ78109179
Design and synthesis of fluoroquinophenoxazines that interact with human telomeric G-quadruplexes and their biological effectsQ78615638
Regulation and recognization of the extended G-quadruplex by rutinQ79421555
The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4Q80334969
Spectroscopic studies of the interaction between quercetin and G-quadruplex DNAQ83169135
Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: I. recognizing mixed G-quadruplex in human telomeresQ83370846
Probing the binding affinity of small‐molecule natural products to the G‐quadruplex in C‐myc oncogene by electrospray ionization mass spectrometryQ85097168
P433issue2
P304page(s)127-136
P577publication date2012-04-01
P1433published inNucleic Acid TherapeuticsQ19297428
P1476titleThe interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids
P478volume22

Reverse relations

cites work (P2860)
Q38842716A Nucleus-Imaging Probe That Selectively Stabilizes a Minor Conformation of c-MYC G-quadruplex and Down-regulates c-MYC Transcription in Human Cancer Cells
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Q90333802In Silico Screening and Binding Characterization of Small Molecules toward a G-Quadruplex Structure Formed in the Promoter Region of c-MYC Oncogene
Q37711622Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
Q35832995Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach
Q89081589Natural Aromatic Compounds as Scaffolds to Develop Selective G-Quadruplex Ligands: From Previously Reported Berberine Derivatives to New Palmatine Analogues
Q34778696Prospect of bioflavonoid fisetin as a quadruplex DNA ligand: a biophysical approach
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Q35353405Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics
Q55068987Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations.
Q47265475Telomerase Inhibitors from Natural Products and Their Anticancer Potential

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