Synergistic antitumor effect of adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase and nucleoside analogs for human breast carcinoma in vitro and in vivo

scientific article published on 14 July 2015

Synergistic antitumor effect of adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase and nucleoside analogs for human breast carcinoma in vitro and in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2147/DDDT.S81717
P8608Fatcat IDrelease_tnrk2l5mlrftxiebovbjixd6la
P932PMC publication ID4507493
P698PubMed publication ID26203222

P50authorXinyu ZhengQ56995221
P2093author name stringBo Chen
Miao Tang
Wenqian Wang
Anning He
Cong Zu
P2860cites workInhibition of renal cancer cell growth in vitro and in vivo with oncolytic adenovirus armed short hairpin RNA targeting Ki-67 encoding mRNA.Q39952467
Improved effects of a double suicide gene system on prostate cancer cells by targeted regulation of prostate-specific membrane antigen promoter and enhancerQ39986008
Targeting gene therapy for hepatocarcinoma cells with the E. coli purine nucleoside phosphorylase suicide gene system directed by a chimeric alpha-fetoprotein promoter.Q39992610
Utility of TK/GCV in the context of highly effective oncolysis mediated by a serotype 3 receptor targeted oncolytic adenovirusQ40111393
An armed oncolytic adenovirus system, ZD55-gene, demonstrating potent antitumoral efficacyQ40598664
Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosolQ40768668
Bystander effects of cancer cell lines transduced with the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster and synergistic enhancement by hydroxyureaQ40792292
New method for titration of virus infectivity by immunostainingQ41752471
Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacyQ43653603
Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancerQ43842247
Mitochondrial amplification of death signals determines thymidine kinase/ganciclovir-triggered activation of apoptosis.Q44107370
Therapy of peritoneal carcinomatosis from colon cancer with oncolytic adenovirusesQ45871906
Telomerase-specific oncolytic virotherapy for human cancer with the hTERT promoterQ50607338
Global cancer statisticsQ22241238
Drosophila melanogaster deoxyribonucleoside kinase activates gemcitabineQ27654114
Development and trends of surgical modalities for breast cancer in China: a review of 16-year dataQ31115506
Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.Q34245096
Antiviral drug discovery and development: where chemistry meets with biomedicineQ34437304
Mesenchymal stem cell-based NK4 gene therapy in nude mice bearing gastric cancer xenograftsQ34710895
Influence of the bystander effect on HSV-tk/GCV gene therapy. A reviewQ34791457
Update on gene therapy approaches for cancer.Q36189470
Suicide genes for cancer therapyQ36738278
Clinical management of adverse events in adjuvant therapy for hormone-responsive early breast cancerQ36949426
Management of locally advanced breast cancer: evolution and current practiceQ36999513
Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2.Q37184919
Update on rescue therapies in patients with lamivudine-resistant chronic hepatitis BQ38132740
STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy.Q39393385
The multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster as a therapeutic suicide gene of breast cancer cellsQ39524207
Retrovirus-mediated Drosophila melanogaster multisubstrate deoxyribonucleoside kinase gene therapy of gastric cancer cells in vitro and in vivo.Q39671803
Tissue specific cytotoxicity of colon cancer cells mediated by nanoparticle-delivered suicide gene in vitro and in vivoQ39899579
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
Drosophila melanogasterQ130888
breast carcinomaQ18555947
P304page(s)3301-3312
P577publication date2015-07-14
P1433published inDrug Design, Development and TherapyQ2566724
P1476titleSynergistic antitumor effect of adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase and nucleoside analogs for human breast carcinoma in vitro and in vivo
P478volume9

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cites work (P2860)
Q99711729Gemcitabine resistance in triple-negative breast cancer cells can be reverted by Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol
Q92569130Recombinant deoxyribonucleoside kinase from Drosophila melanogaster can improve gemcitabine based combined gene/chemotherapy for targeting cancer cells

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