Involvement of the AcrAB-TolC efflux pump in the resistance, fitness, and virulence of Enterobacter cloacae

scientific article published on 30 January 2012

Involvement of the AcrAB-TolC efflux pump in the resistance, fitness, and virulence of Enterobacter cloacae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.05509-11
P932PMC publication ID3318359
P698PubMed publication ID22290971

P50authorMargarita PozaQ88651452
German BouQ42555605
P2093author name stringGermán Bou
María Merino
Ana Fernández
Astrid Pérez
Susana Mallo
Soraya Rumbo-Feal
Maria del Carmen Fernández
María P Cabral
P2860cites workThe AcrAB RND efflux system from the live vaccine strain of Francisella tularensis is a multiple drug efflux system that is required for virulence in miceQ80457520
Enterobacter spp.: pathogens poised to flourish at the turn of the centuryQ24683746
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An RND-type efflux system in Borrelia burgdorferi is involved in virulence and resistance to antimicrobial compoundsQ28472526
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Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmidQ29614535
Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and sequence of the region required for their replication in Pseudomonas aeruginosaQ29615291
Conformational flexibility in the multidrug efflux system protein AcrA.Q30159879
The phytoalexin-inducible multidrug efflux pump AcrAB contributes to virulence in the fire blight pathogen, Erwinia amylovora.Q33196665
Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium.Q33501883
Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulenceQ33558978
Suppression of hypersensitivity of Escherichia coli acrB mutant to organic solvents by integrational activation of the acrEF operon with the IS1 or IS2 elementQ33996066
Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loopsQ34320714
Emergence in Spain of a multidrug-resistant Enterobacter cloacae clinical isolate producing SFO-1 extended-spectrum beta-lactamaseQ34741562
Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulenceQ35036525
Critical role of multidrug efflux pump CmeABC in bile resistance and in vivo colonization of Campylobacter jejuniQ35164856
A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumpsQ35721631
Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pumpQ35921687
A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infectionQ36044684
Multidrug-resistance efflux pumps - not just for resistanceQ36538111
Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitnessQ37015168
Functional role of bacterial multidrug efflux pumps in microbial natural ecosystemsQ37389801
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A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulansQ39601017
EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coliQ39678782
The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABCQ39679800
Comprehensive studies of drug resistance mediated by overexpression of response regulators of two-component signal transduction systems in Escherichia coliQ39734904
The AcrAB-TolC efflux system of Salmonella enterica serovar Typhimurium plays a role in pathogenesis.Q40293277
The nucleotide sequence of pACYC184Q40536516
Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosaQ40721285
Expression of multidrug efflux pump genes acrAB-tolC, mdfA, and norE in Escherichia coli clinical isolates as a function of fluoroquinolone and multidrug resistanceQ42111161
Roles of TolC-dependent multidrug transporters of Escherichia coli in resistance to beta-lactamsQ42113108
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolateQ42130215
The cation-uptake regulators AdcR and Fur are necessary for full virulence of Streptococcus suisQ44305225
Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system.Q47261465
Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium.Q50084995
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectEnterobacter cloacaeQ4038096
P304page(s)2084-2090
P577publication date2012-01-30
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleInvolvement of the AcrAB-TolC efflux pump in the resistance, fitness, and virulence of Enterobacter cloacae
P478volume56

Reverse relations

cites work (P2860)
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