scholarly article | Q13442814 |
P2093 | author name string | David Goltzman | |
Lucie Canaff | |||
Geoffrey N Hendy | |||
Hiroshi Kaji | |||
Jean-François Vanbellinghen | |||
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Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling | Q24290996 | ||
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation | Q24291618 | ||
Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2 | Q24293576 | ||
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression | Q24297027 | ||
Menin, the product of the MEN1 gene, is a nuclear protein | Q24310070 | ||
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus | Q24313196 | ||
Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD | Q24316533 | ||
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors | Q24337658 | ||
ModBase, a database of annotated comparative protein structure models, and associated resources | Q24613729 | ||
Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein | Q27670797 | ||
ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids | Q27860850 | ||
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1 | Q28243243 | ||
Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene | Q28249576 | ||
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung | Q28253904 | ||
Positional cloning of the gene for multiple endocrine neoplasia-type 1 | Q28307577 | ||
Characterization of the mouse Men1 gene and its expression during development | Q28505998 | ||
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c | Q28506197 | ||
Menin is required in cranial neural crest for palatogenesis and perinatal viability | Q28513298 | ||
Activin inhibits pituitary prolactin expression and cell growth through Smads, Pit-1 and menin | Q28564414 | ||
Cell cycle regulation of menin expression | Q28582170 | ||
A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors | Q28592210 | ||
Comparative protein structure modeling using Modeller | Q29615142 | ||
Menin represses JunD-activated transcription by a histone deacetylase-dependent mechanism | Q30779195 | ||
Differential binding of the Menin tumor suppressor protein to JunD isoforms. | Q32061489 | ||
Autosomal recessive juvenile parkinsonism maps to 6q25.2-q27 in four ethnic groups: detailed genetic mapping of the linked region | Q34386289 | ||
The logic of TGFbeta signaling. | Q34522372 | ||
Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8. | Q34612025 | ||
Parathyroid tumor development involves deregulation of homeobox genes | Q35098325 | ||
Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway | Q35663471 | ||
Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter | Q35978041 | ||
Hereditary hormone excess: genes, molecular pathways, and syndromes | Q35999772 | ||
Menin and TGF-beta superfamily member signaling via the Smad pathway in pituitary, parathyroid and osteoblast | Q36185316 | ||
Mechanisms of disease: multiple endocrine neoplasia type 1-relation to chromatin modifications and transcription regulation. | Q36615929 | ||
Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective | Q37347306 | ||
Cellular functions of menin. | Q37696452 | ||
Role of menin in bone development | Q39736696 | ||
Menin expression modulates mesenchymal cell commitment to the myogenic and osteogenic lineages | Q39847891 | ||
Activity and function of the nuclear factor kappaB pathway in human parathyroid tumors. | Q42487214 | ||
Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. | Q42801463 | ||
Global expression profiling of sex cord stromal tumors from Men1 heterozygous mice identifies altered TGF-beta signaling, decreased Gata6 and increased Csf1r expression | Q44980967 | ||
Menin inactivation leads to loss of transforming growth factor beta inhibition of parathyroid cell proliferation and parathyroid hormone secretion | Q47937066 | ||
Menin missense mutants encoded by the MEN1 gene that are targeted to the proteasome: restoration of expression and activity by CHIP siRNA. | Q51544455 | ||
Expression and functional analysis of menin in a multiple endocrine neoplasia type 1 (MEN1) patient with somatic loss of heterozygosity in chromosome 11q13 and unidentified germline mutation of the MEN1 gene. | Q51788318 | ||
Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs. | Q52550786 | ||
Clinical features of multiple endocrine neoplasia type 1 (MEN1) phenocopy without germline MEN1 gene mutations: analysis of 20 Japanese sporadic cases with MEN1. | Q53914105 | ||
Multiple endocrine neoplasia type 1 (MEN1) gene mutations in a subset of patients with sporadic and familial primary hyperparathyroidism target the coding sequence but spare the promoter region. | Q54471962 | ||
Deregulation of anti-Mullerian hormone/BMP and transforming growth factor-beta pathways in Leydig cell lesions developed in male heterozygous multiple endocrine neoplasia type 1 mutant mice. | Q54544183 | ||
Clinical testing for multiple endocrine neoplasia type 1 in a DNA diagnostic laboratory. | Q54680442 | ||
Mouse embryo fibroblasts lacking the tumor suppressor menin show altered expression of extracellular matrix protein genes. | Q54739178 | ||
Mutation Analysis of the MEN1 Gene in Multiple Endocrine Neoplasia Type 1, Familial Acromegaly and Familial Isolated Hyperparathyroidism | Q57423374 | ||
Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism | Q58862086 | ||
Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1 | Q73557853 | ||
Internally shortened menin protein as a consequence of alternative RNA splicing due to a germline deletion in the multiple endocrine neoplasia type 1 gene | Q73794693 | ||
Thymic carcinoids in multiple endocrine neoplasia type 1 | Q74791955 | ||
Mutation analysis of the MEN1 gene in Belgian patients with multiple endocrine neoplasia type 1 and related diseases | Q77794377 | ||
Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex | Q79166838 | ||
Multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas in Japan | Q81828264 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | multiple endocrine neoplasia | Q1553018 |
multiple endocrine neoplasia type 1 | Q3347154 | ||
P304 | page(s) | 8584-8597 | |
P577 | publication date | 2012-01-24 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Impaired transforming growth factor-β (TGF-β) transcriptional activity and cell proliferation control of a menin in-frame deletion mutant associated with multiple endocrine neoplasia type 1 (MEN1). | |
P478 | volume | 287 |
Q35111480 | Bilateral granulosa cell tumors: a novel malignant manifestation of multiple endocrine neoplasia 1 syndrome found in a patient with a rare menin in-frame deletion |
Q49957735 | Current and emerging therapies for PNETs in patients with or without MEN1. |
Q47948643 | Epigenetic regulation by the menin pathway |
Q64964682 | Evolution of Our Understanding of the Hyperparathyroid Syndromes: A Historical Perspective. |
Q37619445 | Genetic and epigenetic mutations of tumor suppressive genes in sporadic pituitary adenoma |
Q50290116 | MEN1 binds SMAD2/3:SMAD4 heterotrimer |
Q28266645 | Novel MEN 1 gene findings in rare sporadic insulinoma--a case control study |
Q40977644 | Novel association of MEN1 gene mutations with parathyroid carcinoma. |
Q45316767 | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
Q97887355 | Unusual Combination of MEN-1 and the Contiguous Gene Deletion Syndrome of CAH and Ehlers-Danlos Syndrome (CAH-X) |
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