Can an immune-regulatory vaccine prevent HIV infection?

scientific article published in March 2012

Can an immune-regulatory vaccine prevent HIV infection? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1586/ERI.11.178
P8608Fatcat IDrelease_q4nvhed5yzfn3fsrfg6ojbn4d4
P932PMC publication ID3318911
P698PubMed publication ID22397564
P5875ResearchGate publication ID221684228

P50authorEdecio Cunha-NetoQ38543773
Jorge Elias Kalil FilhoQ56378220
Matthias von HerrathQ64532773
P2093author name stringTobias Boettler
P2860cites workThe failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?Q24652185
Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infectionQ27318086
Reduced CD4 T cell activation and in vitro susceptibility to HIV-1 infection in exposed uninfected Central AfricansQ27473420
Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removalQ28469094
A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responsesQ28742853
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trialQ28972526
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in ThailandQ29547531
T-cell quality in memory and protection: implications for vaccine designQ30014840
HIV disease progression: immune activation, microbes, and a leaky gut.Q33295161
A multicenter, randomized, double-blind, placebo-controlled trial of recombinant human interleukin-10 in HIV-infected subjectsQ33335327
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS.Q33709283
DNA immunization to prevent autoimmune diabetesQ33855482
Rational antibody-based HIV-1 vaccine design: current approaches and future directionsQ33937285
HIV preferentially infects HIV-specific CD4+ T cellsQ33958893
An HIV vaccine--challenges and prospectsQ34013570
High levels of viral replication contrast with only transient changes in CD4(+) and CD8(+) cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinxQ34348128
Th17 and regulatory T cells: implications for AIDS pathogenesisQ34395054
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.Q34569888
Plasma levels of soluble CD14 independently predict mortality in HIV infectionQ34764002
Glycerol monolaurate prevents mucosal SIV transmissionQ34957016
Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infectionQ34994754
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccineQ35009558
Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanismQ35029947
Natural versus adaptive regulatory T cellsQ35092554
Interleukin-10 promoter polymorphisms influence HIV-1 susceptibility and primary HIV-1 pathogenesisQ35109877
Association of IL-10-promoter genetic variants with the rate of CD4 T-cell loss, IL-10 plasma levels, and breadth of cytotoxic T-cell lymphocyte response during chronic HIV-1 infectionQ35632906
The paradox of simian immunodeficiency virus infection in sooty mangabeys: active viral replication without disease progressionQ35650877
Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10.Q35845894
HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.Q35848896
Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation.Q36845770
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.Q36891917
FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivoQ36915916
Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigensQ36954734
CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infectionQ37195654
Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challengeQ37232824
HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysisQ37413781
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN responseQ37452359
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?Q37519312
Inhibition of acute in vivo human immunodeficiency virus infection by human interleukin 10 treatment of SCID mice implanted with human fetal thymus and liver.Q37687694
Depletion of regulatory T cells in HIV infection is associated with immune activationQ38881101
Persistent immune activation in HIV-1 infection is associated with progression to AIDS.Q39060564
Suppressed cellular alloimmune responses in HIV-exposed seronegative female sex workers.Q39104486
Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent mannerQ42107193
Decreased immune activation in resistance to HIV-1 infection is associated with an elevated frequency of CD4(+)CD25(+)FOXP3(+) regulatory T cellsQ43468180
HIV‐exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV‐dependent host factorsQ43753402
Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults.Q44167410
Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cellsQ44986020
Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patientsQ45609885
Cytokine pattern in relation to disease progression in human immunodeficiency virus-infected children.Q45765515
The fate of human Treg cells.Q45886217
Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremiaQ48023288
Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.Q50638760
Passive immunization with human neutralizing monoclonal antibodies against HIV-1 in macaque models: experimental approaches.Q51791621
Pre-seroconversion immune status predicts the rate of CD4 T cell decline following HIV infection.Q51998041
CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.Q52010705
Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral loadQ58034113
HIV vaccine failure prompts Merck to halt trialQ59098676
IL-10-secreting T cells from HIV-infected pregnant women downregulate HIV-1 replication: effect enhanced by antiretroviral treatmentQ61762161
Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapseQ73153290
Low-level CD4+ T cell activation is associated with low susceptibility to HIV-1 infectionQ81375635
P433issue3
P304page(s)299-305
P577publication date2012-03-01
P1433published inExpert Review of Anti-infective TherapyQ15734432
P1476titleCan an immune-regulatory vaccine prevent HIV infection?
P478volume10

Reverse relations

cites work (P2860)
Q51622254Immunomodulation and infection: back to the future.
Q38554795Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology

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