Testosterone supplementation in male obese Zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure

scientific article published on 23 January 2012

Testosterone supplementation in male obese Zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/HYPERTENSIONAHA.111.180943
P8608Fatcat IDrelease_f5v6yrh5brhyjojz3jdicuewry
P932PMC publication ID3319027
P698PubMed publication ID22275530

P50authorRadu IliescuQ44192077
P2093author name stringJane F Reckelhoff
Deborah D Davis
Kuichang Yuan
Licy L Yanes
Mohadetheh Moulana
Lorraine C Racusen
Arnaldo Lopez Ruiz
P2860cites workAdverse events associated with testosterone administrationQ24601802
Androgen-dependent angiotensinogen and renin messenger RNA expression in hypertensive ratsQ28319565
Renal vascular cytochrome P450-derived eicosanoids in androgen-induced hypertensionQ28567826
Gender differences in the regulation of blood pressureQ33947308
Progressive renal vascular proliferation and injury in obese Zucker ratsQ34076149
Age-dependent glomerular damage in the rat. Dissociation between glomerular injury and both glomerular hypertension and hypertrophy. Male gender as a primary risk factorQ34156239
Androgen regulation of rat renal angiotensinogen messenger RNA expressionQ34574911
Androgen-dependent hypertension is mediated by 20-hydroxy-5,8,11,14-eicosatetraenoic acid-induced vascular dysfunction: role of inhibitor of kappaB KinaseQ34780122
Testosterone-dependent hypertension and upregulation of intrarenal angiotensinogen in Dahl salt-sensitive rats.Q34943188
Low testosterone associated with obesity and the metabolic syndrome contributes to sexual dysfunction and cardiovascular disease risk in men with type 2 diabetesQ35060256
Androgens and cardiovascular diseaseQ35146318
Induction of calcium-dependent nitric oxide synthases by sex hormones.Q35404786
Testosterone therapy in the ageing male: what about the prostate?Q35947307
Changes in renal hemodynamics and structure in the aging kidney; sexual dimorphism and the nitric oxide systemQ36093763
The triad of erectile dysfunction, hypogonadism and the metabolic syndrome.Q36575143
Diabetes, obesity, and erectile dysfunctionQ37422721
Androgens and obesityQ37737022
Testosterone and cardiovascular disease: an old idea with modern clinical implications.Q37792292
Endogenous testosterone, endothelial dysfunction, and cardiovascular events in men with nondialysis chronic kidney disease.Q39736220
Testosterone replacement therapy improves insulin sensitivity and decreases high sensitivity C-reactive protein levels in hypogonadotropic hypogonadal young male patientsQ39907789
Low serum testosterone and increased mortality in men with coronary heart diseaseQ42853956
Effects of intramuscular testosterone undecanoate on body composition and bone mineral density in female-to-male transsexualsQ43003217
Reduced total testosterone concentrations in young healthy South Asian men are partly explained by increased insulin resistance but not by altered adiposityQ43021363
Association of low testosterone with metabolic syndrome and its components in middle-aged Japanese men.Q43118139
Androgens augment proximal tubule transportQ44853232
The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men.Q44968760
Losing the war against obesity: the need for a developmental perspectiveQ45151151
Sex differences in the pressor response to angiotensin II when the endogenous renin-angiotensin system is blockedQ46765345
Sexual hormone abnormalities in male patients with renal failureQ48677676
The effects of sex steroids on plasma levels of marker proteins of endothelial cell functioning.Q50884906
Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats.Q50910155
Relationships among insulin resistance, obesity, diagnosis of the metabolic syndrome and cardio-metabolic risk.Q51373422
Plasma oestradiol-17 beta and testosterone concentrations as possible causes of the infertility of congenitally obese Zucker ratsQ71238792
Gender differences in development of hypertension in spontaneously hypertensive rats: role of the renin-angiotensin systemQ73371712
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
testosteroneQ1318776
testosteroneQ27863114
P304page(s)726-731
P577publication date2012-01-23
P1433published inHypertensionQ5958695
P1476titleTestosterone supplementation in male obese Zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure
P478volume59

Reverse relations

cites work (P2860)
Q59795653A new approach to study the sex differences in adipose tissue
Q47773403Cardiovascular and Metabolic Consequences of Testosterone Supplements in Young and Old Male Spontaneously Hypertensive Rats: Implications for Testosterone Supplements in Men.
Q34309465Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function
Q36528013Early life stress induces renal dysfunction in adult male rats but not female rats
Q36861790Exogenous Testosterone, Aging, and Changes in Behavioral Response of Gonadally Intact Male Mice
Q43226072Exogenous testosterone, finasteride and castration effects on testosterone, insulin, zinc and chromium in adult male rats.
Q52958024Flaxseed suppressed prostatic epithelial proliferation in a rat model of benign prostatic hyperplasia.
Q35243264Genetic and phenotypic variation in UGT2B17, a testosterone-metabolizing enzyme, is associated with BMI in males
Q28394967Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors
Q39792087Low dose of methyltestosterone in ovariectomised rats improves baroreflex sensitivity without geno- and cytotoxicity
Q35437230Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats
Q38669622Sex Differences in Vascular Physiology and Pathophysiology: Estrogen and Androgen Signaling in Health and Disease
Q43146276Sex and gender differences in cardiovascular, renal and metabolic diseases
Q34820497Sex and gender differences in control of blood pressure
Q33848782The Effect of Physical Resistance Training on Baroreflex Sensitivity of Hypertensive Rats.
Q37366613Transient Decrease in Circulatory Testosterone and Homocysteine Precedes the Development of Metabolic Syndrome Features in Fructose-Fed Sprague Dawley Rats.

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