Non-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors.

scientific article published in January 1993

Non-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1476-5381.1993.TB13466.X
P932PMC publication ID1907728
P698PubMed publication ID7679031
P5875ResearchGate publication ID15520195

P50authorSteve P. WatsonQ37383398
Alastair J. BarrQ40296353
P2093author name stringS P Watson
A J Barr
P2860cites workThe human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissuesQ24311634
Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptorQ28208664
Molecular characterisation, expression and localisation of human neurokinin‐3 receptorQ28209225
The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of the cDNA from tracheal and gastric tissuesQ28279130
Molecular cloning, structural characterization and functional expression of the human substance P receptorQ28279939
Highly selective agonists for substance P receptor subtypesQ28337533
Neurokinin3-receptors are linked to inositol phospholipid hydrolysis in the guinea-pig ileum longitudinal muscle-myenteric plexus preparation.Q35755491
G proteins and G-protein-coupled receptors: structure, function and interactionsQ36472539
Mammalian Tachykinin ReceptorsQ37178892
Pharmacological properties of a potent and selective nonpeptide substance P antagonistQ37621800
Tachykinin receptor types: Classification and membrane signalling mechanismsQ37760972
Structural basis of beta-adrenergic receptor function.Q41235089
STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLEQ41397208
Tissue selectivity of substance P alkyl esters: suggesting multiple receptorsQ41542740
High affinity transport of taurine and beta-alanine and low affinity transport of gamma-aminobutyric acid by a single transport system in cultured glioma cellsQ41686638
Selectivity and specificity of new, non-peptide, quinuclidine antagonists of substance P.Q41687016
Characterization of receptors for substance P in human astrocytoma cells: radioligand binding and inositol phosphate formationQ41825883
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glandsQ41922155
Identification and characterization of substance P receptors on LRM55 glial cellsQ42487162
Effects of tachykinins on inositol phospholipid hydrolysis in slices of hamster urinary bladderQ42565898
Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345Q42710885
Continuous human glioma-derived cell lines UC-11MG and UC-302MG. Morphologic, immunocytochemical and chromosomal characterizationQ42819333
Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cellsQ46417448
Substance P induced hydrolysis of inositol phospholipids in guinea-pig ileum and rat hypothalamusQ46669265
Structure-activity studies of neurokinin A.Q46686837
Species differences in affinities of non-peptide antagonists for substance p receptorsQ46925772
A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) ReceptorQ67679280
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttachykinin receptorQ426034
P304page(s)223-227
P577publication date1993-01-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleNon-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors
P478volume108

Reverse relations

cites work (P2860)
Q37333022A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists
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Q42117930Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea-pig ileum and proximal colon.
Q78048601Effect of MEN 11467, a new tachykinin NK1 receptor antagonist, in acute rectocolitis induced by acetic acid in guinea-pigs
Q41790903Effect of the tachykinin NK1 receptor antagonists, RP 67580 and SR 140333, on electrically-evoked substance P release from rat spinal cord
Q71549319Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema
Q34793730Effects of RP 67580, a tachykinin NK1 receptor antagonist, on a primary afferent-evoked response of ventral roots in the neonatal rat spinal cord
Q42370128Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B.
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