scholarly article | Q13442814 |
P2093 | author name string | Thompson SA | |
Wafford KA | |||
Whiting PJ | |||
P2860 | cites work | Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human [...] | Q24316082 |
Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors | Q24322955 | ||
Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons | Q24616501 | ||
Molecular and cellular mechanisms of general anaesthesia | Q34291163 | ||
Actions of anaesthetics and avermectin on GABAA chloride channels in mammalian dorsal root ganglion neurones | Q35756774 | ||
The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon | Q38330309 | ||
The effects of general anaesthetics on GABAergic synaptic transmission | Q39463817 | ||
Potentiation of the effects of GABA by pentobarbitone | Q40244040 | ||
Functional domains of GABAA receptors. | Q40453946 | ||
Allosteric modulations of the nicotinic acetylcholine receptor. | Q40487666 | ||
The role of the GABAA receptor/chloride channel complex in anesthesia. | Q40852807 | ||
General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium | Q41086586 | ||
Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions | Q41550313 | ||
The influence of the gamma 2L subunit on the modulation of responses to GABAA receptor activation | Q41570882 | ||
Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids | Q41865800 | ||
A novel allosteric modulatory site on the GABAA receptor beta subunit | Q42285400 | ||
Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture | Q43652740 | ||
gamma-Aminobutyric acid (GABA)- and barbiturate-mediated 36Cl- uptake in rat brain synaptoneurosomes: evidence for rapid desensitization of the GABA receptor-coupled chloride ion channel | Q48285707 | ||
Molecular Determinants of General Anesthetic Action: Role of GABAA Receptor Structure | Q48317942 | ||
Actions of pentobarbital on rat brain receptors expressed in Xenopus oocytes. | Q48318700 | ||
Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family | Q48341437 | ||
Differential subcellular distribution of the alpha 6 subunit versus the alpha 1 and beta 2/3 subunits of the GABAA/benzodiazepine receptor complex in granule cells of the cerebellar cortex | Q48403002 | ||
The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. | Q48524991 | ||
Effects of two volatile anesthetics and a volatile convulsant on the excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat | Q48621075 | ||
The effect of subunit composition of rat brain GABAA receptors on channel function | Q48875490 | ||
Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital | Q49066197 | ||
Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations. | Q49082328 | ||
GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital | Q49124909 | ||
Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors | Q49138038 | ||
Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes. | Q49154995 | ||
Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons. | Q51617593 | ||
Potentiation of gamma-aminobutyric acidA receptor Cl- current correlates with in vivo anesthetic potency. | Q51626396 | ||
Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture. | Q51640586 | ||
Propofol activates GABAA receptor-chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat. | Q51654860 | ||
The effects of pentobarbital and related compounds on frog motoneurons | Q51875846 | ||
A second pathway of activation of the Torpedo acetylcholine receptor channel | Q67700974 | ||
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones | Q68837946 | ||
Barbiturates | Q69048105 | ||
(-)Pentobarbital opens ion channels of long duration in cultured mouse spinal neurons | Q72857379 | ||
Single channel currents activated by gamma-aminobutyric acid, muscimol, and (-)-pentobarbital in cultured mouse spinal neurons | Q72936590 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 521-527 | |
P577 | publication date | 1996-02-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination | |
P478 | volume | 117 |
Q33925435 | (+)- and (-)-cis-2-aminomethylcyclopropanecarboxylic acids show opposite pharmacology at recombinant rho(1) and rho(2) GABA(C) receptors |
Q35853220 | 2'-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors |
Q41169281 | 5-(N, N-Hexamethylene) amiloride is a GABA-A ρ1 receptor positive allosteric modulator |
Q49023322 | A functional comparison of the antagonists bicuculline and picrotoxin at recombinant GABAA receptors |
Q42606895 | A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation |
Q42626295 | Activation and block of recombinant GABA(A) receptors by pentobarbitone: a single-channel study |
Q39746791 | Activation of alpha6-containing GABAA receptors by pentobarbital occurs through a different mechanism than activation by GABA. |
Q50741465 | Activation of protein kinase C induces gamma-aminobutyric acid type A receptor internalization in Xenopus oocytes. |
Q35045899 | Activity of chlormethiazole at human recombinant GABAA and NMDA receptors |
Q41820907 | Allosteric modulators affect the efficacy of partial agonists for recombinant GABA(A) receptors |
Q40126424 | Alpha subunit isoform influences GABA(A) receptor modulation by propofol |
Q35600442 | Altered GABAA receptor subunit expression and pharmacology in human Angelman syndrome cortex |
Q90463024 | Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA |
Q44050766 | Amobarbital inhibits K(+)-stimulated glucose oxidation in cerebellar granule neurons by two mechanisms |
Q30491170 | Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes |
Q38620815 | Approach to the Complicated Alcohol Withdrawal Patient. |
Q35134381 | Barbiturates for acute neurological and neurosurgical emergencies--do they still have a role? |
Q28300800 | Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor |
Q30871360 | Characterisation of cell damage and death in embryonic mesencephalic tissue: a study on ultrastructure, vital stains and protease activity |
Q51580747 | Chimeric GABAA/glycine receptors: expression and barbiturate pharmacology. |
Q40766770 | Cis-4-amino-crotonic acid activates alpha 6 subunit-containing GABA(A) but not GABA(C) receptors in granule cells of adult rat cerebellar slices |
Q44297317 | Competitive GABA(A) receptor antagonists increase the proportion of functional high-affinity alpha6 subunit-containing receptors in granule cells of adult rat cerebellum. |
Q44535859 | Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats. |
Q46102112 | Contrasting actions of a convulsant barbiturate and its anticonvulsant enantiomer on the α1 β3 γ2L GABAA receptor account for their in vivo effects |
Q28551559 | Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors |
Q37076097 | Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states |
Q34749269 | Drug interactions at GABA(A) receptors |
Q28345866 | Effects of gamma-HCH and delta-HCH on human recombinant GABA(A) receptors: dependence on GABA(A) receptor subunit combination |
Q48455994 | Effects of propofol and pentobarbital on ligand binding to GABAA receptors suggest a similar mechanism of action |
Q51419519 | Electroencephalographic effects of thiopentone and its enantiomers in the rat. |
Q44164040 | Electrophysiological actions of gamma-aminobutyric acid and clomethiazole on recombinant GABA(A) receptors. |
Q43665517 | Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. |
Q48431797 | Evidence that GABA rho subunits contribute to functional ionotropic GABA receptors in mouse cerebellar Purkinje cells |
Q42455967 | Expression of 10 GABA(A) receptor subunit messenger RNAs in the motor-related thalamic nuclei and basal ganglia of Macaca mulatta studied with in situ hybridization histochemistry |
Q28293660 | Fine mapping of a sedative-hypnotic drug withdrawal locus on mouse chromosome 11 |
Q35853243 | Flavan-3-ol esters: new agents for exploring modulatory sites on GABA(A) receptors |
Q34660416 | Flavonoid modulation of GABA(A) receptors |
Q28370472 | Functional characteristics of recombinant human GABA(A) receptors containing the epsilon-subunit |
Q42685003 | Furosemide modulation of GABA(A) receptors in dopaminergic neurones of the rat substantia nigra. |
Q37137819 | GABA(A) receptor properties in catastrophic infantile epilepsy |
Q48624478 | GABA(A) receptor subunits in the rat hippocampus I: immunocytochemical distribution of 13 subunits. |
Q37104140 | GABA(A) receptors in normal development and seizures: friends or foes? |
Q50646751 | GABA-site antagonism and pentobarbital actions do not depend on the alpha-subunit type in the recombinant rat GABA receptor. |
Q33798108 | General anaesthetic action at transmitter-gated inhibitory amino acid receptors |
Q24595524 | General anaesthetic actions on ligand-gated ion channels |
Q43102870 | High-frequency gamma oscillations coexist with low-frequency gamma oscillations in the rat visual cortex in vitro |
Q34315069 | How theories evolved concerning the mechanism of action of barbiturates |
Q40835327 | Identification of amino acids involved in histamine potentiation of GABA A receptors |
Q48900585 | Identification of an amino acid defining the distinct properties of murine beta1 and beta3 subunit-containing GABA(A) receptors |
Q42547650 | Inhibitory effects of corymine, an alkaloidal component from the leaves of Hunteria zeylanica, on glycine receptors expressed in Xenopus oocytes |
Q24321527 | Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit |
Q37855931 | Insights into the structure and pharmacology of GABA(A) receptors |
Q41991553 | Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes. |
Q41856798 | Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies |
Q24608968 | International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update |
Q43057276 | Intrinsic activation of GABA(A) receptors suppresses epileptiform activity in the cerebral cortex of immature mice |
Q53880191 | Kinetic analysis of the agonistic and blocking properties of pentobarbital on recombinant rat alpha(1)beta(2)gamma(2S) GABA(A) receptor channels. |
Q89619699 | Lack of Neurosteroid Selectivity at δ vs. γ2-Containing GABAA Receptors in Dentate Granule Neurons |
Q40762864 | Lateral mobility and anchoring of recombinant GABAA receptors depend on subunit composition. |
Q34442065 | Mechanism of action of general anaesthetics--new information from molecular pharmacology |
Q35134568 | MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity |
Q31882849 | Modulation of GABA(A) receptors by benzodiazepines and barbiturates is autonomous of PKC activation |
Q51433701 | Modulation of bistratified cell IPSPs and basket cell IPSPs by pentobarbitone sodium, diazepam and Zn2+: dual recordings in slices of adult rat hippocampus. |
Q48481235 | Modulatory and direct effects of propofol on recombinant GABAA receptors expressed in xenopus oocytes: influence of alpha- and gamma2-subunits |
Q92734047 | Molecular and Regulatory Mechanisms of Desensitization and Resensitization of GABAA Receptors with a Special Reference to Propofol/Barbiturate |
Q33691541 | Molecular and functional diversity of the expanding GABA-A receptor gene family |
Q48596188 | Multiple modulatory effects of the neuroactive steroid pregnanolone on GABAA receptor in frog pituitary melanotrophs |
Q35566485 | Mutation at the putative GABA(A) ion-channel gate reveals changes in allosteric modulation |
Q36824549 | NSAIDs modulate GABA-activated currents via Ca(2+)-activated Cl(-) channels in rat dorsal root ganglion neurons |
Q34429004 | Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties [corrected; erratum to be published] |
Q35971833 | Neurosteroids and GABA-A Receptor Function |
Q52641631 | Neurosteroids in Schizophrenia: Pathogenic and Therapeutic Implications. |
Q41108241 | Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes |
Q58702367 | Opportunities and Challenges for Single-Unit Recordings from Enteric Neurons in Awake Animals |
Q35142240 | Paradoxical reactions to benzodiazepines in intravenous sedation: a report of 2 cases and review of the literature |
Q44238738 | Pentobarbital depressant effects are independent of GABA receptors in auditory thalamic neurons |
Q44633561 | Pentobarbital modulates intrinsic and GABA-receptor conductances in thalamocortical inhibition |
Q42014137 | Pentobarbital produces activation and block of {alpha}1{beta}2{gamma}2S GABAA receptors in rapidly perfused whole cells and membrane patches: divergent results can be explained by pharmacokinetics |
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Q41954486 | Piracetam and TRH analogues antagonise inhibition by barbiturates, diazepam, melatonin and galanin of human erythrocyte D-glucose transport. |
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Q34678100 | Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro |
Q35047079 | Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors |
Q30828480 | Spike Timing Rigidity Is Maintained in Bursting Neurons under Pentobarbital-Induced Anesthetic Conditions |
Q35041394 | Stereoselective interaction of thiopentone enantiomers with the GABA(A) receptor |
Q28237504 | Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels |
Q73734637 | Structural domains of the human GABAA receptor 3 subunit involved in the actions of pentobarbital |
Q31813374 | Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation. |
Q48259481 | Subunit dependent modulation of GABAA receptor function by neuroactive steroids |
Q43168431 | Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor |
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Q43132136 | The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes |
Q28343937 | The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations |
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Q34414887 | The anaesthetic action and modulation of GABAA receptor activity by the novel water-soluble aminosteroid Org 20599. |
Q24646448 | The anti-convulsant stiripentol acts directly on the GABA(A) receptor as a positive allosteric modulator |
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Q30401509 | The dual modulatory effects of efavirenz on GABAA receptors are mediated via two distinct sites |
Q35098727 | The effect of age on the discriminative stimulus effects of ethanol and its GABA(A) receptor mediation in cynomolgus monkeys |
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Q35144759 | Unique general anesthetic binding sites within distinct conformational states of the nicotinic acetylcholine receptor |
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