Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene.

scientific article published in December 1996

Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID190959
P698PubMed publication ID8970991

P2093author name stringW E Miller
N Raab-Traub
K L Fries
P2860cites workA novel RING finger protein interacts with the cytoplasmic domain of CD40Q24306382
Involvement of CRAF1, a relative of TRAF, in CD40 signalingQ24306746
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell deathQ24312157
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell deathQ24312211
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorQ24318280
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformationQ28249159
Mutations in the p53 gene occur in diverse human tumour typesQ28249770
p21 is a universal inhibitor of cyclin kinasesQ28257305
Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxinQ28299110
p53 mutations in human cancersQ28302973
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor familyQ28307399
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40Q28610812
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53Q29547773
p53-dependent apoptosis modulates the cytotoxicity of anticancer agentsQ29615031
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasiaQ29615437
Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative diseaseQ43936463
p53 mutation in human nasopharyngeal carcinomasQ44195191
Immunohistology of Epstein-Barr virus-associated antigens in B cell disorders from immunocompromised individualsQ44953164
Epstein-Barr virus gene expression in nasopharyngeal carcinomaQ45205828
Epstein-Barr virus-induced B-cell lymphoma after renal transplantation: acyclovir therapy and transition from polyclonal to monoclonal B-cell proliferationQ45800684
DNA of Epstein-Barr virus VIII: B95-8, the previous prototype, is an unusual deletion derivativeQ45803144
The differentiated form of nasopharyngeal carcinoma contains Epstein-Barr virus DNA.Q45835618
Expression of Epstein-Barr virus-encoded proteins in nasopharyngeal carcinoma.Q45841044
Latent and replicating forms of Epstein-Barr virus DNA in lymphomas and lymphoproliferative diseasesQ45845223
The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa BQ45876441
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Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.Q53505779
An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.Q53541156
Thymocyte apoptosis induced by p53-dependent and independent pathways.Q54242475
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Wild-type p53 activates transcription in vitroQ59054260
A20 zinc finger protein inhibits TNF and IL-1 signalingQ59487872
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p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical featuresQ67841746
The EBV-encoded LMP1 protein inhibits p53-triggered apoptosis but not growth arrestQ71761308
Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathwaysQ72831542
Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53Q72871721
Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint controlQ29616465
mdm2 expression is induced by wild type p53 activityQ29618316
Participation of p53 protein in the cellular response to DNA damageQ29618319
p53 is required for radiation-induced apoptosis in mouse thymocytesQ29620281
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6Q29622924
Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-kappa B activityQ30452167
EBV gene expression in an NPC-related tumour.Q33576708
Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cellsQ33929593
Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinomaQ33937673
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoproteinQ33938629
Inhibition of p53 transactivation required for transformation by adenovirus early 1B proteinQ34343950
The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity.Q34561178
Two TNF receptorsQ35231014
Structural analyses of the Epstein-Barr virus BamHI A transcriptsQ35832657
The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor.Q35841701
Apoptosis and programmed cell death in immunityQ36135180
Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformationQ36575274
Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas.Q36628203
Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma.Q36697762
Alterations of the p53 gene in nasopharyngeal carcinomaQ36698270
Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23Q36806063
Expression of the Epstein-Barr virus BamHI A fragment in nasopharyngeal carcinoma: evidence for a viral protein expressed in vivoQ36822172
Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.Q37013182
Wild-type p53 is a cell cycle checkpoint determinant following irradiationQ37152060
Epstein-Barr virus markers in a series of Burkitt's lymphomas from the West Nile District, UgandaQ38892203
Nasopharyngeal carcinoma. X. Presence of Epstein-Barr genomes in separated epithelial cells of tumours in patients from Singapore, Tunisia and KenyaQ38970951
Expression of LMP1 in epithelial cells leads to the activation of a select subset of NF-kappa B/Rel family proteinsQ39870850
All three domains of the Epstein-Barr virus-encoded latent membrane protein LMP-1 are required for transformation of rat-1 fibroblasts.Q40044497
DNA damage, oncogenesis and the p53 tumour-suppressor geneQ40389197
Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53Q40806210
p53 is frequently mutated in Burkitt's lymphoma cell linesQ41082472
Expression of epstein-barr virus-encoded growth-transformation-associated proteins in lymphoproliferations of bone-marrow transplant recipientsQ41154554
Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosisQ41343773
Upregulation of bcl-2 by the Epstein-Barr virus latent membrane protein LMP1: a B-cell-specific response that is delayed relative to NF-kappa B activation and to induction of cell surface markersQ41447311
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.Q41508377
Biological activities of p53 mutants in Burkitt's lymphoma cellsQ41555135
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.Q41563742
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosisQ41563751
Absence of p53 gene mutations in primary nasopharyngeal carcinomasQ41604318
Growth suppression of human breast cancer cells by the introduction of a wild-type p53 geneQ41661999
Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell deathQ41678654
Expression of immune regulatory molecules in Epstein-Barr virus-associated nasopharyngeal carcinomas with prominent lymphoid stroma. Evidence for a functional interaction between epithelial tumor cells and infiltrating lymphoid cellsQ41807177
Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virusQ41976287
Bcl-2 proto-oncogene expression in Epstein-Barr-virus-associated nasopharyngeal carcinomaQ42507253
SV40 T antigen abrogates p53-mediated transcriptional activity.Q42805922
Association of human papillomavirus types 16 and 18 E6 proteins with p53.Q43701619
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
membrane proteinQ423042
apoptotic processQ14599311
P304page(s)8653-8659
P577publication date1996-12-01
P1433published inJournal of VirologyQ1251128
P1476titleEpstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene
P478volume70

Reverse relations

cites work (P2860)
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