| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Rafael Garesse | Q43130709 |
| Marcos T Oliveira | Q57317221 | ||
| P2093 | author name string | Laurie S Kaguni | |
| P2860 | cites work | The human DNA ligase III gene encodes nuclear and mitochondrial proteins | Q22009425 |
| Premature ageing in mice expressing defective mitochondrial DNA polymerase | Q24294365 | ||
| Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA | Q24299860 | ||
| Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis | Q24307994 | ||
| Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling | Q24310134 | ||
| PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1 | Q24312106 | ||
| Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates | Q24312975 | ||
| The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. | Q24315784 | ||
| Human Dna2 is a nuclear and mitochondrial DNA maintenance protein | Q24316108 | ||
| MTERF3 is a negative regulator of mammalian mtDNA transcription | Q24323198 | ||
| TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein | Q24323366 | ||
| A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine | Q24537551 | ||
| The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells | Q24559899 | ||
| Reconstitution of a minimal mtDNA replisome in vitro | Q24564147 | ||
| Drosophila mitochondrial transcription factor B1 modulates mitochondrial translation but not transcription or DNA copy number in Schneider cells. | Q40450206 | ||
| Identification of a putative p53 binding sequence within the human mitochondrial genome | Q40484325 | ||
| Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress | Q40518641 | ||
| Drosophila mitochondrial transcription factor B2 regulates mitochondrial DNA copy number and transcription in schneider cells | Q40570833 | ||
| Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein | Q40593842 | ||
| Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide. | Q40783678 | ||
| Recombination of mitochondrial DNA in skeletal muscle of individuals with multiple mitochondrial DNA heteroplasmy | Q41809981 | ||
| The tamas gene, identified as a mutation that disrupts larval behavior in Drosophila melanogaster, codes for the mitochondrial DNA polymerase catalytic subunit (DNApol-gamma125). | Q42558679 | ||
| A family of putative transcription termination factors shared amongst metazoans and plants | Q42669375 | ||
| Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons | Q43076986 | ||
| Axonal mitochondrial transport and potential are correlated | Q44901240 | ||
| Mitochondrial endonuclease activities specific for apurinic/apyrimidinic sites in DNA from mouse cells | Q45062083 | ||
| Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes. Protective role of targeting 8-oxoguanine glycosylase to mitochondria | Q46423498 | ||
| MTERF3, the most conserved member of the mTERF-family, is a modular factor involved in mitochondrial protein synthesis. | Q47070106 | ||
| In vitro transcription termination activity of the Drosophila mitochondrial DNA-binding protein DmTTF. | Q47070390 | ||
| Mitochondrial nucleoid and transcription factor A. | Q47652488 | ||
| Glial cell-specific differences in response to alkylation damage | Q48374437 | ||
| Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster. | Q52583090 | ||
| Bleomycin-induced double-strand breaks in mitochondrial DNA of Drosophila cells are repaired. | Q52683713 | ||
| Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication. | Q52945782 | ||
| Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice. | Q53379421 | ||
| Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging? | Q53611452 | ||
| DNA polymerase gamma from Xenopus laevis. I. The identification of a high molecular weight catalytic subunit by a novel DNA polymerase photolabeling procedure. | Q54241838 | ||
| Mitochondrial point mutations do not limit the natural lifespan of mice. | Q55043447 | ||
| Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing | Q59444619 | ||
| Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma | Q69820389 | ||
| Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress | Q73351562 | ||
| Response: The mitochondrial DNA replication bubble has not burst | Q73702388 | ||
| The mitochondrial DNA replication bubble has not burst | Q73702391 | ||
| Concluding remarks: The mitochondrial DNA replication bubble has not burst | Q73837274 | ||
| Glial cell type-specific responses to menadione-induced oxidative stress | Q73978549 | ||
| DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice | Q80799366 | ||
| Heterologous mitochondrial DNA recombination in human cells | Q80889065 | ||
| Bidirectional replication initiates at sites throughout the mitochondrial genome of birds | Q81041100 | ||
| Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis | Q82081316 | ||
| Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53. | Q37421120 | ||
| The MTERF family proteins: mitochondrial transcription regulators and beyond. | Q37444322 | ||
| Mitochondrial dysfunction and Parkinson's disease genes: insights from Drosophila | Q37530204 | ||
| Mitochondrial DNA replication and repair: all a flap | Q37533073 | ||
| 30 years and a long way into p53 research | Q37589207 | ||
| Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? | Q37936915 | ||
| Mitochondrial single-stranded DNA-binding protein from Drosophila embryos. Physical and biochemical characterization | Q38291687 | ||
| Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis | Q38324711 | ||
| Mitochondrial transcription factor B2 is essential for metabolic function in Drosophila melanogaster development | Q39259724 | ||
| Effects of ectopic expression of Drosophila DNA glycosylases dOgg1 and RpS3 in mitochondria | Q39522041 | ||
| Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling | Q39811992 | ||
| Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair | Q39823278 | ||
| Replication of animal mitochondrial DNA. | Q40103664 | ||
| Rapid evolution of animal mitochondrial DNA | Q24597162 | ||
| Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity | Q24624288 | ||
| Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene | Q24633708 | ||
| The mitochondrial transcription termination factor mTERF modulates replication pausing in human mitochondrial DNA | Q24669735 | ||
| Relative abundance of the human mitochondrial transcription system and distinct roles for h-mtTFB1 and h-mtTFB2 in mitochondrial biogenesis and gene expression | Q24672119 | ||
| Composition and dynamics of human mitochondrial nucleoids | Q24683007 | ||
| Contrahelicase activity of the mitochondrial transcription termination factor mtDBP | Q24816444 | ||
| Disruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivo | Q27335303 | ||
| Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs | Q28143253 | ||
| P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA | Q28184423 | ||
| Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria | Q28204177 | ||
| The biologic clock: the mitochondria? | Q28249363 | ||
| Flap endonuclease 1: a central component of DNA metabolism | Q28266199 | ||
| Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion | Q28301052 | ||
| mTERF2 regulates oxidative phosphorylation by modulating mtDNA transcription | Q28512464 | ||
| DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase | Q28513159 | ||
| Rat MYH, a glycosylase for repair of oxidatively damaged DNA, has brain-specific isoforms that localize to neuronal mitochondria | Q28580215 | ||
| Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons | Q28590748 | ||
| Mitochondrial dysfunction and oxidative damage in parkin-deficient mice | Q28593859 | ||
| Do mtDNA deletions drive premature aging in mtDNA mutator mice? | Q28742556 | ||
| A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine | Q29547303 | ||
| Animal mitochondrial genomes | Q29547362 | ||
| Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants | Q29615627 | ||
| Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging | Q29616056 | ||
| p53 and metabolism | Q29617084 | ||
| Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice | Q29619811 | ||
| Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro | Q30431649 | ||
| Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress | Q33259243 | ||
| The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures | Q33288345 | ||
| Prominent mitochondrial DNA recombination intermediates in human heart muscle. | Q33757916 | ||
| Does mtDNA nucleoid organization impact aging? | Q33889067 | ||
| Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA. | Q33893664 | ||
| Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila | Q33900458 | ||
| The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster | Q34048626 | ||
| Double-strand breaks of mouse muscle mtDNA promote large deletions similar to multiple mtDNA deletions in humans | Q34062921 | ||
| Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma | Q34116250 | ||
| Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice | Q34201844 | ||
| Mismatch-specific 3'----5' exonuclease associated with the mitochondrial DNA polymerase from Drosophila embryos | Q34299429 | ||
| Mammalian mitochondria possess homologous DNA recombination activity | Q34406718 | ||
| Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2. | Q34572837 | ||
| Inherited mitochondrial diseases of DNA replication | Q34692482 | ||
| Maintenance of human rearranged mitochondrial DNAs in long-term cultured transmitochondrial cell lines | Q34733032 | ||
| Human mitochondrial DNA is packaged with TFAM. | Q34908739 | ||
| Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome | Q34974795 | ||
| Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand. | Q35130981 | ||
| Mitochondrial single-stranded DNA-binding protein is required for mitochondrial DNA replication and development in Drosophila melanogaster | Q35581161 | ||
| Origin and direction of replication in mitochondrial DNA molecules from the genus Drosophila | Q35739342 | ||
| DNA polymerase gamma, the mitochondrial replicase | Q35799966 | ||
| Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes. | Q35865328 | ||
| Oxidative stress, mitochondria and mtDNA-mutator mice | Q36663410 | ||
| Initiation and beyond: multiple functions of the human mitochondrial transcription machinery | Q36692560 | ||
| Mitochondria as chi. | Q36724311 | ||
| DNA replication and transcription in mammalian mitochondria | Q36780113 | ||
| A pivotal role for p53: balancing aerobic respiration and glycolysis | Q36841610 | ||
| Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria | Q36845992 | ||
| Physiological and biochemical defects in carboxyl-terminal mutants of mitochondrial DNA helicase | Q36855814 | ||
| Differential phenotypes of active site and human autosomal dominant progressive external ophthalmoplegia mutations in Drosophila mitochondrial DNA helicase expressed in Schneider cells | Q36860866 | ||
| Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion | Q36860874 | ||
| Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53 | Q37077431 | ||
| What causes mitochondrial DNA deletions in human cells? | Q37096545 | ||
| Mitochondrial DNA repair in aging and disease | Q37140173 | ||
| Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress | Q37151889 | ||
| Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA. | Q37169833 | ||
| Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis | Q37187824 | ||
| Functional importance of the conserved N-terminal domain of the mitochondrial replicative DNA helicase | Q37262673 | ||
| Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks | Q37273617 | ||
| The pathophysiology of mitochondrial disease as modeled in the mouse | Q37287583 | ||
| Human heart mitochondrial DNA is organized in complex catenated networks containing abundant four-way junctions and replication forks | Q37372049 | ||
| The mitochondrial theory of aging: insight from transgenic and knockout mouse models | Q37378136 | ||
| The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells | Q37385875 | ||
| P433 | issue | 7-8 | |
| P921 | main subject | mitochondrial DNA | Q27075 |
| P304 | page(s) | 489-502 | |
| P577 | publication date | 2010-02-01 | |
| P1433 | published in | Experimental Gerontology | Q15766996 |
| P1476 | title | Animal models of mitochondrial DNA transactions in disease and ageing | |
| P478 | volume | 45 |
| Q52768299 | A comprehensive approach to determining BER capacities and their change with aging in Drosophila melanogaster mitochondria by oligonucleotide microarray. |
| Q37135534 | Animal Mitochondrial DNA Replication. |
| Q33860426 | Can we define maternal age as a genetic disease? |
| Q41994021 | Developmental and hormone-induced changes of mitochondrial electron transport chain enzyme activities during the last instar larval development of maize stem borer, Chilo partellus (Lepidoptera: Crambidae). |
| Q34711876 | Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation |
| Q35569785 | Evolution of the metazoan mitochondrial replicase. |
| Q35077024 | Genetic mosaic analysis of a deleterious mitochondrial DNA mutation in Drosophila reveals novel aspects of mitochondrial regulation and function |
| Q38240141 | Invertebrate models for coenzyme q10 deficiency. |
| Q36054913 | Mechanism of transcription initiation by the yeast mitochondrial RNA polymerase |
| Q51733446 | Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy. |
| Q27929976 | Mitochondrial genome maintenance: roles for nuclear nonhomologous end-joining proteins in Saccharomyces cerevisiae |
| Q37753231 | Modeling mitochondrial encephalomyopathy in Drosophila |
| Q35884861 | Molecular mechanisms for age-associated mitochondrial deficiency in skeletal muscle. |
| Q36435715 | Muscle-specific overexpression of the catalytic subunit of DNA polymerase γ induces pupal lethality in Drosophila melanogaster |
| Q38153032 | Replicating animal mitochondrial DNA. |
| Q36002469 | SUV3 helicase is required for correct processing of mitochondrial transcripts |
| Q34692029 | Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase |
| Q35914995 | Selfish Mitochondrial DNA Proliferates and Diversifies in Small, but not Large, Experimental Populations of Caenorhabditis briggsae. |
| Q34364128 | Selfish little circles: transmission bias and evolution of large deletion-bearing mitochondrial DNA in Caenorhabditis briggsae nematodes. |
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