Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection

scientific article published on 28 December 2015

Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1005338
P932PMC publication ID4692439
P698PubMed publication ID26709698
P5875ResearchGate publication ID288659245

P2093author name stringMatthew A Schaller
Steven L Kunkel
Toshihiro Ito
Ronald M Allen
Danielle N Kroetz
Cleyton Cavallaro
P2860cites workType I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factorsQ24303448
Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modificationQ24304218
Suppression of the antiviral response by an influenza histone mimicQ24307599
Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cellsQ24314284
IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complexQ24336912
Cross-regulation of TNF and IFN-alpha in autoimmune diseasesQ24556513
A diverse range of gene products are effectors of the type I interferon antiviral responseQ24626018
Protein ISGylation modulates the JAK-STAT signaling pathwayQ24672739
The IRF family, revisitedQ24678497
The SET-domain protein superfamily: protein lysine methyltransferasesQ24811144
Interferon-inducible antiviral effectorsQ27486790
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage responseQ27670940
Pattern recognition receptors and inflammationQ27861115
Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.Q27863922
Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemiaQ28212879
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?Q28217338
Re-emergence of fatal human influenza A subtype H5N1 diseaseQ28247143
Avian influenza A (H5N1) infection in humansQ28274603
Influenza: old and new threatsQ28296381
CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infectionQ28508659
Twist mediates suppression of inflammation by type I IFNs and AxlQ28509359
Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infectionQ28511064
IRF-7 is the master regulator of type-I interferon-dependent immune responsesQ28511410
Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virusQ28589623
Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arraysQ28646554
Monocyte recruitment during infection and inflammationQ29620067
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in miceQ30351800
Targeted prostaglandin E2 inhibition enhances antiviral immunity through induction of type I interferon and apoptosis in macrophages.Q30361326
Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in miceQ30405962
Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assemblyQ30421691
Harnessing alveolar macrophages for sustained mucosal T-cell recall confers long-term protection to mice against lethal influenza challenge without clinical diseaseQ30431135
Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10.Q30438825
Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infectionQ31157006
A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in miceQ33216000
Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 proteinQ33810694
Type I interferon signaling regulates Ly6C(hi) monocytes and neutrophils during acute viral pneumonia in miceQ33839474
Critical role of airway macrophages in modulating disease severity during influenza virus infection of miceQ33964051
The critical role of Notch ligand Delta-like 1 in the pathogenesis of influenza A virus (H1N1) infectionQ34071370
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypesQ35035956
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.Q35060864
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis.Q52935183
GM-CSF in the Lung Protects against Lethal Influenza InfectionQ57202915
Type I interferons produced by dendritic cells promote their phenotypic and functional activationQ61473768
Activation of dual T cell signaling pathways by the chemokine RANTESQ71768178
RANTES potentiates antigen-specific mucosal immune responsesQ73311818
Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50Q79369723
Chemokine regulation of the inflammatory response to a low-dose influenza infection in CCR2-/- miceQ79442109
Distinct differentiation potential of blood monocyte subsets in the lungQ79717943
Pfizer's JAK inhibitor sails through phase 3 in rheumatoid arthritisQ84306736
Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes.Q35220547
Type I interferon modulation of cellular responses to cytokines and infectious pathogens: potential role in SLE pathogenesisQ35675517
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responsesQ35785139
Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of γδ T cellsQ36363816
Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugationQ36424059
Influenza and the challenge for immunologyQ36452600
Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease developmentQ36540154
Alveolar macrophages are indispensable for controlling influenza viruses in lungs of pigsQ36540192
Agouti C57BL/6N embryonic stem cells for mouse genetic resourcesQ36562560
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responsesQ36567669
Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfectionsQ37002972
TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4Q37036047
Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resourceQ37100323
Type I IFNs mediate development of postinfluenza bacterial pneumonia in miceQ37241332
Autophagy-inducing protein beclin-1 in dendritic cells regulates CD4 T cell responses and disease severity during respiratory syncytial virus infectionQ37262708
Epigenetic regulation of the alternatively activated macrophage phenotypeQ37381695
Interferons limit inflammatory responses by induction of tristetraprolinQ37659150
Alveolar macrophages transport pathogens to lung draining lymph nodesQ39349537
An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinaseQ39699570
Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient miceQ39759848
Exposure to chemokines during maturation modulates antigen presenting cell function of mature macrophagesQ40410725
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLsQ41057373
Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infectionQ41992035
GM-CSF mediates alveolar macrophage proliferation and type II cell hypertrophy in SP-D gene-targeted miceQ43481101
Macrophage Turnover Kinetics in the Lungs of Mice Infected with Streptococcus pneumoniaeQ44015551
Conditional gene targeting in macrophages and granulocytes using LysMcre mice.Q44554898
CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortalityQ44752156
Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunityQ45018410
Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.Q45159348
Cytokine (tumor necrosis factor, IL-6, and IL-8) production by respiratory syncytial virus-infected human alveolar macrophagesQ45214714
Differential onset of apoptosis in influenza A virus H5N1- and H1N1-infected human blood macrophages.Q45406038
Annual summary of vital statistics: 2005.Q47575504
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P304page(s)e1005338
P577publication date2015-12-28
P1433published inPLOS PathogensQ283209
P1476titleType I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection
P478volume11

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