The range and distribution of murine central nervous system cells infected with the gamma(1)34.5- mutant of herpes simplex virus 1.

scientific article published in July 1997

The range and distribution of murine central nervous system cells infected with the gamma(1)34.5- mutant of herpes simplex virus 1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID191798
P698PubMed publication ID9188630

P50authorBernard RoizmanQ4893595
P2093author name stringN S Markovitz
D Baunoch
P2860cites workHerpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in miceQ24645922
Pathogenicity in mice of strains of herpes simplex virus which are resistant to acyclovir in vitro and in vivoQ28366019
NeuN, a neuronal specific nuclear protein in vertebratesQ28510657
Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herQ33780588
Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infectionQ34483710
Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant gliomaQ34616722
Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequenceQ34779144
A quantitative study of the thalamocortical and other synapses in layer IV of pyramidal cells projecting from mouse SmI cortex to the caudate-putamen nucleusQ48874879
Amygdaloid projections to the frontal cortex and the striatum in the ratQ48930750
The organization of the projection from the cerebral cortex to the striatum in the rat.Q53799354
Mesostriatal projections in BALB/c and CBA mice: a quantitative retrograde neuroanatomical tracing studyQ69108300
Morphology of the rat brain ventricles, ependyma, and periventricular structuresQ71031542
Afferent and efferent pathways of the vibrissal region of primary motor cortex in the mouseQ71741656
Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent modelsQ35611914
The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells.Q35853252
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-Q35964369
The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in miceQ36250741
THE PATHOGENESIS OF HERPES VIRUS ENCEPHALITIS. I. VIRUS PATHWAYS TO THE NERVOUS SYSTEM OF SUCKLING MICE DEMONSTRATED BY FLUORESCENT ANTIBODY STAININGQ36266931
Differential response of human cells to deletions and stop codons in the gamma(1)34.5 gene of herpes simplex virus.Q36638186
Herpes simplex virus 1 RNA-binding protein US11 negatively regulates the accumulation of a truncated viral mRNAQ36820840
Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodiesQ36894567
The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cellsQ36945982
The function of herpes simplex virus genes: a primer for genetic engineering of novel vectorsQ37247688
The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumorsQ37247954
Fiber connections of the basal gangliaQ41200604
An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gI or the putative gJ.Q41462238
The herpes simplex virus type 2 (HG52) variant JH2604 has a 1488 bp deletion which eliminates neurovirulence in miceQ42108318
Herpes simplex encephalitis. A modified indirect immunoperoxidase technique for rapid diagnosis in paraffin-embedded tissueQ42451466
The striato-entopeduncular pathway in the rat. A retrograde transport study with wheatgerm-agglutinin-horseradish peroxidaseQ42489727
In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020: construction and evaluation in rodentsQ43815948
Organization of amygdaloid projections to the prefrontal cortex and associated striatum in the ratQ43887072
Characterization of encephalitis in adult mice induced by intracerebral inoculation of herpes simplex virus type 1 (KOS) and comparison with mutants showing decreased virulenceQ44065763
Herpes simplex encephalitis. Immunohistological demonstration of spread of virus via olfactory pathways in miceQ44254795
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in cultureQ44460699
A variant of herpes simplex virus type 2 strain HG52 with a 1.5 kb deletion in RL between 0 to 0.02 and 0.81 to 0.83 map units is non-neurovirulent for miceQ44732468
Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb.Q45776581
Bilateral electroretinographic changes induced by unilateral intra-visual cortex inoculation of herpes simplex virus type 1 in BALB/c miceQ45779462
Anterograde tracing of trigeminal afferent pathways from the murine tooth pulp to cortex using herpes simplex virus type 1.Q45789282
Mouse hepatitis virus and herpes simplex virus move along different CNS pathways.Q45789850
Neuron to neuron transmission of herpes simplex virus. Transport of virus from skin to brainstem nucleiQ45800384
Histological study of the progression of herpes simplex virus in miceQ45803614
Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cellsQ45823697
Contrasting patterns of virus spread and neuropathology following microinjection of herpes simplex virus into the hippocampus or cerebellum of miceQ45834458
The production of focal herpes encephalitis in mice by stereotaxic inoculation of virus. Anatomical and behavioral effectsQ45836737
Herpes simplex virus encephalitis. Neuroanatomical and neurochemical selectivityQ45837406
Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1.Q45842139
Experimental murine herpes simplex encephalitis: immunohistochemical detection of virus antigensQ45843507
Golgi-like, transneuronal retrograde labelling with CNS injections of herpes simplex virus type 1.Q45847137
Neural spread of herpes simplex virus after anterior chamber inoculation.Q45859585
Detection of herpes simplex virus in the ependyma of experimentally infected mice.Q45860405
Targets of herpes simplex virus type 1 infection in a mouse corneal modelQ45861131
The Pathogenicity of Ribonucleotide Reductase-Null Mutants of Herpes Simplex Virus Type 1 in MiceQ45861716
Stereotaxic microinjection of HSV-1 selectively decreases striatal dopamine concentrations in miceQ48088969
HSV-1 virulence for mice by the intracerebral route is encoded by the BamHI-L DNA fragment containing the cell fusion geneQ48252341
Pathogenesis of herpetic encephalitis in mice after ophthalmic inoculationQ48545760
Retrograde axonal transport and the demonstration of non-specific projections to the cerebral cortex and striatum from thalamic intralaminar nuclei in the rat, cat and monkeyQ48563837
Combined immunocytochemistry and autoradiographic retrograde axonal tracing for identification of transmitters of projection neuronsQ48720919
The distribution of herpes simplex type 1 antigen in mouse central nervous system after different routes of inoculationQ48771156
Topographical organization of amygdaloid projections to the caudatoputamen, nucleus accumbens, and related striatal-like areas of the rat brainQ48819954
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)5560-5569
P577publication date1997-07-01
P1433published inJournal of VirologyQ1251128
P1476titleThe range and distribution of murine central nervous system cells infected with the gamma(1)34.5- mutant of herpes simplex virus 1
P478volume71

Reverse relations

cites work (P2860)
Q27319470A herpes simplex virus-derived replicative vector expressing LIF limits experimental demyelinating disease and modulates autoimmunity
Q38218674Antiglioma oncolytic virotherapy: unattainable goal or a success story in the making?
Q33802747Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice
Q35635064Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements
Q37173279Autophagy and viral neurovirulence
Q33649894B-myb promoter retargeting of herpes simplex virus gamma34.5 gene-mediated virulence toward tumor and cycling cells
Q34516701Cancer stem cells: the final frontier for glioma virotherapy.
Q34341979Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.
Q35023819Functional genomic analysis of herpes simplex virus type 1 counteraction of the host innate response
Q33995752HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applications
Q35863367Herpes simplex virus-based vectors
Q33934056Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells
Q39699288Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins
Q37718569Pre-clinical Assessment of C134, a Chimeric Oncolytic Herpes Simplex Virus, in Mice and Non-human Primates.
Q54233707Questioning the Extreme Neurovirulence of Monkey B Virus (Macacine alphaherpesvirus 1).
Q37945174Spontaneous and Engineered Compensatory HSV Mutants that Counteract the Host Antiviral PKR Response
Q37596491Spread and replication of and immune response to gamma134.5-negative herpes simplex virus type 1 vectors in BALB/c mice
Q30495687TLR2 activation inhibits embryonic neural progenitor cell proliferation
Q35422223The Ebola virus VP35 protein functions as a type I IFN antagonist.
Q35105093The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
Q45722305The herpes simplex virus (HSV) protein ICP34.5 is a virion component that forms a DNA-binding complex with proliferating cell nuclear antigen and HSV replication proteins
Q36548927The herpes simplex virus virulence factor ICP34.5 and the cellular protein MyD116 complex with proliferating cell nuclear antigen through the 63-amino-acid domain conserved in ICP34.5, MyD116, and GADD34.
Q42368523The γ134.5 Neurovirulence Gene of Herpes Simplex Virus 1 Modifies the Exosome Secretion Profile in Epithelial Cells
Q37138701Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs
Q35895914Transcription of the derepressed open reading frame P of herpes simplex virus 1 precludes the expression of the antisense gamma(1)34.5 gene and may account for the attenuation of the mutant virus
Q37028023Trial watch: Oncolytic viruses for cancer therapy
Q39848419Ultrastructural analysis of ICP34.5- herpes simplex virus 1 replication in mouse brain cells in vivo
Q37024346Viral evasion of autophagy
Q33665530Virotherapy against malignant glioma stem cells
Q27491341Viruses and autophagy
Q37791919When autophagy meets viruses: a double-edged sword with functions in defense and offense

Search more.