Systemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes

scientific article published on 25 June 2015

Systemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes is …
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scholarly articleQ13442814

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P356DOI10.3390/IJMS160714428
P932PMC publication ID4519850
P698PubMed publication ID26121298
P5875ResearchGate publication ID279457749

P50authorChak Sing LauQ72123770
V S ChanQ73794465
P2093author name stringWanling Yang
Alfred L H Lee
Rachel C Y Tam
P2860cites workBioGPS: an extensible and customizable portal for querying and organizing gene annotation resourcesQ21183895
Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15(-) Crohn's disease patientsQ24600432
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosusQ24629130
A role for the membrane Golgi protein Ema in autophagy.Q52739371
Systemic lupus erythematosus.Q53495545
Involvement of CLEC16A in activation of astrocytes after LPS treated.Q54343733
Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymusQ60445325
Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymusQ83000727
Polymorphisms at 16p13 are associated with systemic lupus erythematosus in the Chinese populationQ84967748
Expression and function of dectin-1 is defective in monocytes from patients with systemic lupus erythematosus and rheumatoid arthritisQ85267997
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosusQ28261767
A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosusQ28263690
The diabetes susceptibility gene Clec16a regulates mitophagyQ28511990
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in AsiansQ28943338
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.Q29417087
The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation.Q33717079
A genome-wide association study identifies KIAA0350 as a type 1 diabetes geneQ34651283
Intron polymorphism in the KIAA0350 gene is reproducibly associated with susceptibility to type 1 diabetes (T1D) in the Han Chinese populationQ34932373
Chromosomal region 16p13: further evidence of increased predisposition to immune diseases.Q34946418
Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosisQ35008221
Genetic susceptibility to systemic lupus erythematosus in the genomic eraQ35102487
Signaling by myeloid C-type lectin receptors in immunity and homeostasisQ35779708
Drosophila Golgi membrane protein Ema promotes autophagosomal growth and function.Q35935587
Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesisQ36186747
Macroautophagy is deregulated in murine and human lupus T lymphocytesQ36194783
Myeloid dendritic cells display downregulation of C-type lectin receptors and aberrant lectin uptake in systemic lupus erythematosusQ36993270
The role of mannose-binding lectin in systemic lupus erythematosus.Q37063384
From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A.Q38084534
C-type lectins in immunity: recent developmentsQ38305222
Association of systemic lupus erythematosus with promoter polymorphisms of the mannose-binding lectin geneQ38333047
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection.Q38874311
Functional evaluation of the role of C-type lectin domain family 16A at the chromosome 16p13 locusQ39062856
Association of mannose binding lectin (MBL) gene polymorphism and serum MBL concentration with characteristics and progression of systemic lupus erythematosusQ42099627
Summarizing disease features over time: I. Adjusted mean SLEDAI derivation and application to an index of disease activity in lupus.Q43552335
Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in AustraliansQ46466235
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectsystemic lupus erythematosusQ1485
P304page(s)14428-14440
P577publication date2015-06-25
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleSystemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes
P478volume16

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cites work (P2860)
Q984672489q34 & 16p13 chromosome duplications in autism
Q30981879Human CLEC16A regulates autophagy through modulating mTOR activity

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